Inhibition of RNA polymerase and RNA synthesis in rat liver nuclei by Bacillus thuringiensis exotoxin (thuringiensin)

1975 ◽  
Vol 40 (9) ◽  
pp. 2912-2922 ◽  
Author(s):  
A. Čihák ◽  
K. Horská ◽  
K. Šebesta
1967 ◽  
Vol 120 (1) ◽  
pp. 136-157 ◽  
Author(s):  
Ronal R. MacGregor ◽  
H.R. Mahler

1970 ◽  
Vol 116 (2) ◽  
pp. 177-180 ◽  
Author(s):  
F. Novello ◽  
L. Fiume ◽  
F. Stirpe

1. α-Amanitin inhibits in vitro the RNA polymerase solubilized from isolated rat liver nuclei. 2. In contrast with previous observations with whole nuclei, the inhibition occurs approximately to the same extent in the presence and in the absence of ammonium sulphate. 3. Evidence is presented that the toxin acts by interacting with the enzyme itself and not with DNA or other components.


1969 ◽  
Vol 171 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Dennis D. Cunningham ◽  
Sooja Cho ◽  
Donald F. Steiner

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