Selective Cleavage of O-(Dimethoxytrityl) Protecting Group with Sodium Periodate

2002 ◽  
Vol 67 (4) ◽  
pp. 502-508 ◽  
Author(s):  
Dominik Rejman ◽  
Šárka Králíková ◽  
Zdeněk Točík ◽  
Radek Liboska ◽  
Ivan Rosenberg
Keyword(s):  
Organic Solvents ◽  
Sodium Periodate ◽  
Protecting Group ◽  
Reaction Conditions

Sodium periodate in aqueous organic solvents selectively removes, under mild reaction conditions, the O-(dimethoxytrityl) protecting group. Selectivity of the cleavage was studied using the nucleoside derivatives protected by various types of groups commonly used in nucleoside and nucleotide chemistry.

Cleavage of the Epimines of 1,6-Anhydrohexoses with Fluoride Anion

2005 ◽  
Vol 70 (12) ◽  
pp. 2075-2085 ◽  
Author(s):  
Jiří Kroutil ◽  
Klára Jeništová
Keyword(s):  
Fluoride Anion ◽  
Ring Cleavage ◽  
Protecting Group ◽  
Reaction Conditions ◽  
Aziridine Ring ◽  
Cleavage Reactions ◽  
Derivatives Of ◽  
Fluoro Derivatives

Aziridine ring cleavage reactions of five N-nosylepimines (2-6) having D-talo, D-galacto, D-manno, and D-allo configurations with potassium hydrogendifluoride under various reaction conditions have been performed. The cleavage regioselectively afforded diaxial isomers of vicinal amino-fluoro derivatives of 1,6-anhydro-β-D-gluco- and mannopyranose 7-11 in 51-94% yields. Removal of 2-nitrobenzenesulfonyl protecting group with benzenethiol has been attempted in the case of compound 10.

Highly efficient oxidation of sulfides with sodium periodate catalyzed by reusable silica supported Mn(Br8TPP)Cl and Mn(TPP)Cl catalysts under various reaction conditions

2009 ◽  
Vol 353 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Valiollah Mirkhani ◽  
Majid Moghadam ◽  
Shahram Tangestaninejad ◽  
Iraj Mohammdpoor-Baltork ◽  
Hadi Kargar ◽  
...  
Keyword(s):  
Sodium Periodate ◽  
Reaction Conditions ◽  
Oxidation Of Sulfides ◽  
Highly Efficient

Ozone Degradation of Alcohols, Ketones, Ethers and Hydroxybenzenes: Determination of Pathways and Kinetic Parameters

2013 ◽  
Vol 16 (1) ◽  
Author(s):  
Slavcho K. Rakovsky ◽  
Metody P. Anachkov ◽  
Vesselin I. Iliev ◽  
Alexander E. Eliyas
Keyword(s):  
Kinetic Parameters ◽  
Thermodynamic Parameters ◽  
Organic Compounds ◽  
Organic Solvents ◽  
Practical Importance ◽  
Reaction Conditions ◽  
Ozone Reactions ◽  
Reaction Schemes

AbstractThe review, based on 92 references, is focused on degradation of organics by ozonation and it comprises various classes of oxygen-containing organic compounds - alcohols, ketones, ethers and hydroxybenzenes. The mechanisms of a multitude of ozone reactions with these compounds in organic solvents are discussed in details, presenting the respective reaction schemes and the corresponding kinetic parameters are given and some thermodynamic parameters are also listed. The dependencies of the kinetics and the mechanism of the ozonation reactions on the structure of the compounds, on the medium and on the reaction conditions are revealed. The various possible applications of ozonolysis are specified and discussed. All these reactions have practical importance for the protection of the environment.

9-BBN:  An Amino Acid Protecting Group for Functionalization of Amino Acid Side Chains in Organic Solvents

2002 ◽  
Vol 4 (8) ◽  
pp. 1249-1251 ◽  
Author(s):  
William H. Dent ◽  
W. Randal Erickson ◽  
Stephen C. Fields ◽  
Marshall H. Parker ◽  
Eric G. Tromiczak
Keyword(s):  
Amino Acid ◽  
Organic Solvents ◽  
Side Chains ◽  
Protecting Group ◽  
Amino Acid Side Chains

scholarly journals Cyclization into Hydrindanes Using Samarium Diiodide: Stereochemical Features Depending on the Protecting Group

2016 ◽  
Vol 11 (8) ◽  
pp. 1934578X1601100
Author(s):  
Masakazu Sono ◽  
Yukiko Nishibuchi ◽  
Norihito Yamaguchi ◽  
Motoo Tori
Keyword(s):  
Hydroxy Group ◽  
Samarium Diiodide ◽  
Protecting Group ◽  
Reaction Conditions ◽  
Bicyclic Compounds

Monocyclic compounds bearing ketone and enone moieties in the same molecule can be cyclized to bicyclic compounds initiated by samarium diiodide. The stereochemistry of the products depended on the reaction conditions and also the protecting group of the hydroxy group existed in the molecule. A cyclization mechanism is discussed.

scholarly journals Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls

2020 ◽  
Vol 22 (12) ◽  
pp. 833-843
Author(s):  
Olivier B. C. Monty ◽  
Nicholas Simmons ◽  
Srinivas Chamakuri ◽  
Martin M. Matzuk ◽  
Damian W. Young
Keyword(s):  
Peptide Synthesis ◽  
Solution Phase ◽  
Protecting Group ◽  
Reaction Conditions ◽  
Chemical Libraries
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