AB0121 Cyclic Phosphatidic Acid (CPA) Suppresses Expression of Cartilage Degrading Enzymes Such as MMP-3 and MMP-13, Also Increaces HAS-2 Expression in Inflammatory Rheumatoid Synovial Fibroblasts Induced by IL-1 Beta and/or TNF Alfa

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 931.1-931
Author(s):  
I. Masuda ◽  
K. Okada ◽  
H. Yamanaka ◽  
S. Momohara
Keyword(s):  
Phosphatidic Acid ◽  
Synovial Fibroblasts ◽  
Degrading Enzymes ◽  
Cyclic Phosphatidic Acid

2- O -Carba-oleoyl cyclic phosphatidic acid induces glial proliferation through the activation of lysophosphatidic acid receptor

2018 ◽  
Vol 1681 ◽  
pp. 44-51 ◽  
Author(s):  
Shingo Nakajima ◽  
Mari Gotoh ◽  
Keiko Fukasawa ◽  
Hiromu Murofushi ◽  
Kimiko Murakami-Murofushi
Keyword(s):  
Phosphatidic Acid ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Glial Proliferation ◽  
Cyclic Phosphatidic Acid

scholarly journals Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Tomoaki Higuchi ◽  
Kae Takagi ◽  
Akiko Tochimoto ◽  
Yuki Ichimura ◽  
Takanari Norose ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Phosphatidic Acid ◽  
The Novel ◽  
Novel Treatment ◽  
Cyclic Phosphatidic Acid

Cyclic phosphatidic acid treatment suppress cuprizone-induced demyelination and motor dysfunction in mice

2014 ◽  
Vol 741 ◽  
pp. 17-24 ◽  
Author(s):  
Shinji Yamamoto ◽  
Mari Gotoh ◽  
Yuuki Kawamura ◽  
Kota Yamashina ◽  
Sosuke Yagishita ◽  
...  
Keyword(s):  
Phosphatidic Acid ◽  
Acid Treatment ◽  
Motor Dysfunction ◽  
Cyclic Phosphatidic Acid

scholarly journals Cyclic Phosphatidic Acid Relieves Osteoarthritis Symptoms

2014 ◽  
Vol 10 ◽  
pp. 1744-8069-10-52 ◽  
Author(s):  
Mari Gotoh ◽  
Aya Nagano ◽  
Ryoko Tsukahara ◽  
Hiromu Murofushi ◽  
Toshiro Morohoshi ◽  
...  
Keyword(s):  
Phosphatidic Acid ◽  
Cyclic Phosphatidic Acid

Synthesis of enantiopure 2-carba-cyclic phosphatidic acid and effects of its chirality on biological functions

2011 ◽  
Vol 1811 (4) ◽  
pp. 271-277 ◽  
Author(s):  
Emi Nozaki ◽  
Mari Gotoh ◽  
Harumi Hotta ◽  
Shuwa Hanazawa ◽  
Susumu Kobayashi ◽  
...  
Keyword(s):  
Phosphatidic Acid ◽  
Biological Functions ◽  
Cyclic Phosphatidic Acid
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