SAT0558 New Generation Translocator Protein Pet Tracers To Image Arthritis by Macrophage Targeting in Rheumatoid Arthritis Patients: A Proof of Concept Study:

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2016-eular.4215 ◽

2016 ◽

Vol 75 (Suppl 2) ◽

pp. 871.2-871

Author(s):

S. Bruijnen ◽

Y. Gent ◽

M. Huisman ◽

A. Windhorst ◽

M. Kassiou ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Translocator Protein ◽

Proof Of Concept ◽

Pet Tracers ◽

Concept Study ◽

Macrophage Targeting ◽

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Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity

BMC Medical Research Methodology ◽

10.1186/s12874-017-0416-3 ◽

2017 ◽

Vol 17 (1) ◽

Author(s):

Feng Liu ◽

Stephen J. Walters ◽

Steven A. Julious

Keyword(s):

Rheumatoid Arthritis ◽

Proof Of Concept ◽

Concept Study ◽

Design Considerations

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Safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the monoclonal antibody ASK8007 blocking osteopontin in patients with rheumatoid arthritis: a randomised, placebo controlled, proof-of-concept study

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2011-200298 ◽

2011 ◽

Vol 71 (2) ◽

pp. 180-185 ◽

Author(s):

M J H Boumans ◽

J G A Houbiers ◽

P Verschueren ◽

H Ishikura ◽

R Westhovens ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Proof Of Concept ◽

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AB0758 Performance of a therapeutic attempt with oral prednisolone in patients with rheumatoid arthritis and hand osteoarthritis – a proof of concept study

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.3080 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A1020.3-A1021

Author(s):

U. Kiltz ◽

C. von Zabern ◽

F. Heldmann ◽

M. van Werde ◽

B. Mintrop ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Oral Prednisolone ◽

Hand Osteoarthritis ◽

Proof Of Concept ◽

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Imaging disease activity of rheumatoid arthritis by macrophage targeting using second generation translocator protein positron emission tomography tracers

PLoS ONE ◽

10.1371/journal.pone.0222844 ◽

2019 ◽

Vol 14 (9) ◽

pp. e0222844 ◽

Author(s):

S. T. G. Bruijnen ◽

N. J. F. Verweij ◽

Y. Y. J. Gent ◽

M. C. Huisman ◽

A. D. Windhorst ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Positron Emission Tomography ◽

Disease Activity ◽

Second Generation ◽

Translocator Protein ◽

Emission Tomography ◽

Positron Emission ◽

Macrophage Targeting

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Using a Discrete-Choice Experiment in a Decision Aid to Nudge Patients Towards Value-Concordant Treatment Choices in Rheumatoid Arthritis: A Proof-of-Concept Study

Patient Preference and Adherence ◽

10.2147/ppa.s221897 ◽

2020 ◽

Vol Volume 14 ◽

pp. 829-838

Author(s):

Glen S Hazlewood ◽

Deborah A Marshall ◽

Claire EH Barber ◽

Linda C Li ◽

Cheryl Barnabe ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Discrete Choice Experiment ◽

Discrete Choice ◽

Choice Experiment ◽

Decision Aid ◽

Proof Of Concept ◽

Treatment Choices ◽

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Faculty of 1000 evaluation for A Randomized Controlled Trial of an Internal Family Systems-based Psychotherapeutic Intervention on Outcomes in Rheumatoid Arthritis: A Proof-of-Concept Study.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718080056.793484707 ◽

2013 ◽

Author(s):

Joel Block

Keyword(s):

Rheumatoid Arthritis ◽

Randomized Controlled Trial ◽

Family Systems ◽

Controlled Trial ◽

Proof Of Concept ◽

Psychotherapeutic Intervention ◽

Concept Study ◽

Randomized Controlled ◽

Internal Family Systems

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Faculty Opinions recommendation of LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.724435768.793505748 ◽

2015 ◽

Author(s):

Vijay Kuchroo

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Phase I ◽

Interleukin 17 ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

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Targeting interleukin-15 in patients with rheumatoid arthritis: A proof-of-concept study

Arthritis & Rheumatism ◽

10.1002/art.21249 ◽

2005 ◽

Vol 52 (9) ◽

pp. 2686-2692 ◽

Author(s):

Bo Baslund ◽

Niels Tvede ◽

Bente Danneskiold-Samsoe ◽

Per Larsson ◽

Gabriel Panayi ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Proof Of Concept ◽

Concept Study ◽

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The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

Arthritis Research & Therapy ◽

10.1186/ar2438 ◽

2008 ◽

Vol 10 (3) ◽

pp. R67 ◽

Author(s):

Rieke Alten ◽

Hermann Gram ◽

Leo A Joosten ◽

Wim Berg ◽

Joachim Sieper ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Joint Inflammation ◽

Proof Of Concept ◽

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THU0109 Lack of Efficacy of CCR1 Antagonist BMS-817399 in Patients with Moderate to Severe Rheumatoid Arthritis: Results of 12-Week Proof-Of-Concept Study

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.3871 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 215.1-215 ◽

Author(s):

A. Kivitz ◽

P. Maciag ◽

P. Gulati ◽

S. Du ◽

S.E. Connolly ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Proof Of Concept ◽

Severe Rheumatoid Arthritis ◽

Concept Study ◽

Ccr1 Antagonist

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