scholarly journals First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)–Pan-American League of Associations of Rheumatology (PANLAR)

2018 ◽  
Vol 77 (11) ◽  
pp. 1549-1557 ◽  
Author(s):  
Bernardo A Pons-Estel ◽  
Eloisa Bonfa ◽  
Enrique R Soriano ◽  
Mario H Cardiel ◽  
Ariel Izcovich ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Latin American ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Special Focus ◽  
Systemic Lupus ◽  
Assessment Development ◽  
Evaluation Approach

Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams (rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an ‘overarching’ treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings.

Clinical practice guidelines and recommendations for the management of patients with systemic lupus erythematosus: a critical comparison

Rheumatology ◽  
2020 ◽  
Vol 59 (12) ◽  
pp. e165-e168
Author(s):  
Ariel Izcovich ◽  
Graciela S Alarcón ◽  
José A Gómez-Puerta ◽  
Guillermo J Pons-Estel ◽  
Manuel F Ugarte-Gil ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Critical Comparison ◽  
Guidelines And Recommendations

Clinical Practice Guidelines for the Treatment of Systemic Lupus Erythematosus by the Mexican College of Rheumatology

2019 ◽  
Vol 15 (1) ◽  
pp. 3-20
Author(s):  
Daniel Xibillé-Friedmann ◽  
Marcela Pérez-Rodríguez ◽  
Sandra Carrillo-Vázquez ◽  
Everardo Álvarez-Hernández ◽  
Francisco Javier Aceves ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Systemic Lupus

scholarly journals Diagnosis, Monitoring, and Treatment of Systemic Lupus Erythematosus: A Systematic Review of Clinical Practice Guidelines

2015 ◽  
Vol 67 (10) ◽  
pp. 1440-1452 ◽  
Author(s):  
David J. Tunnicliffe ◽  
Davinder Singh-Grewal ◽  
Siah Kim ◽  
Jonathan C. Craig ◽  
Allison Tong
Keyword(s):  
Systematic Review ◽  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Systemic Lupus

scholarly journals Systemic lupus erythematosus: state of the art on clinical practice guidelines

RMD Open ◽  
2018 ◽  
Vol 4 (Suppl 1) ◽  
pp. e000793 ◽  
Author(s):  
Farah Tamirou ◽  
Laurent Arnaud ◽  
Rosaria Talarico ◽  
Carlo Alberto Scirè ◽  
Tobias Alexander ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Disease Management ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Unmet Needs ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Systemic Lupus

Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing-remitting course. The aim of the present work was to identify current available clinical practice guidelines (CPGs) for SLE, to provide their review and to identify physicians’ and patients’ unmet needs. Twenty-three original guidelines published between 2004 and 2017 were identified. Many aspects of disease management are covered, including global disease management, lupus nephritis and neuropsychiatric involvement, management of pregnancies, vaccinations and comorbidities monitoring. Unmet needs relate with disease management of some clinical manifestations and adherence to treatment. Many patient’s unmet needs have been identified starting with faster diagnosis, need for more therapeutic options, guidelines on lifestyle issues, attention to quality of life and adequate education.

Clinical practice guidelines for systemic lupus erythematosus: Recommendations for general clinical management

2016 ◽  
Vol 146 (9) ◽  
pp. 413.e1-413.e14
Author(s):  
María M. Trujillo-Martín ◽  
Iñigo Rúa-Figueroa Fernández de Larrinoa ◽  
Guillermo Ruíz-Irastorza ◽  
José María Pego-Reigosa ◽  
José Mario Sabio Sánchez ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Clinical Practice ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Lupus Erythematosus ◽  
Clinical Management ◽  
Systemic Lupus

scholarly journals Management of children and adolescents with bronchiectasis: summary of the ERS clinical practice guideline

Breathe ◽  
2021 ◽  
Vol 17 (3) ◽  
pp. 210105
Author(s):  
Anne B. Chang ◽  
Keith Grimwood ◽  
Jeanette Boyd ◽  
Rebecca Fortescue ◽  
Zena Powell ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Children And Adolescents ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Clinical Information ◽  
List Type ◽  
European Respiratory Society ◽  
Assessment Development ◽  
Evaluation Approach ◽  
Bronchial Dilatation

Bronchiectasis, characterised by chronic wet/productive cough with recurrent respiratory exacerbations and abnormal bronchial dilatation on computed tomography scans, remains an increasingly recognised but often neglected chronic pulmonary disorder in children and adolescents. An early diagnosis combined with optimal management offers the prospect, at least in some patients, of curing a condition previously considered irreversible. However, unlike in adults, until now no international paediatric guidelines existed. The recently published European Respiratory Society clinical practice guidelines for the management of children and adolescents with bronchiectasis attempts to address this clinical information gap. The guidelines were formulated by panel members comprised of experts from several relevant health fields, the European Lung Foundation and parents of children with bronchiectasis. Systematic reviews and the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach guided the nature and strength of recommendations. The recommendations are grouped into clinically relevant topics: diagnosis, evaluating for underlying causes, defining exacerbations, management, systematic care, monitoring, reversibility and prevention. The guidelines seek to achieve: 1) optimal lung growth, 2) preserved lung function, 3) enhanced quality of life, 4) minimal exacerbations, 5) few or no complications, and 6) if possible, reversal of lung injury for each child/adolescent with bronchiectasis. This review presents example cases that highlight the recommendations of the clinical practice guidelines.Educational aimsThis article is intended for those involved in caring for children/adolescents with bronchiectasis. It aims to inform:Clinicians of the European Respiratory Society recommendations for the diagnosis and management of children/adolescents with bronchiectasis.Adolescents and parents of children/adolescents with bronchiectasis of these recommendations, so as to assist discussions with healthcare teams and help facilitate access to appropriate care.

scholarly journals Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus

2018 ◽  
Vol 45 (10) ◽  
pp. 1426-1439 ◽  
Author(s):  
Stephanie O. Keeling ◽  
Zainab Alabdurubalnabi ◽  
Antonio Avina-Zubieta ◽  
Susan Barr ◽  
Louise Bergeron ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Face To Face ◽  
Assessment Development ◽  
Evaluation Approach ◽  
Grade Method ◽  
Assessment And Monitoring ◽  
Decision Tables

Objective.To develop recommendations for the assessment of people with systemic lupus erythematosus (SLE) in Canada.Methods.Recommendations were developed using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach. The Canadian SLE Working Group (panel of Canadian rheumatologists and a patient representative from Canadian Arthritis Patient Alliance) was created. Questions for recommendation development were identified based on the results of a previous survey of SLE practice patterns of members of the Canadian Rheumatology Association. Systematic literature reviews of randomized trials and observational studies were conducted. Evidence to Decision tables were prepared and presented to the panel at 2 face-to-face meetings and online.Results.There are 15 recommendations for assessing and monitoring SLE, with varying applicability to adult and pediatric patients. Three recommendations focus on diagnosis, disease activity, and damage assessment, suggesting the use of a validated disease activity score per visit and annual damage score. Strong recommendations were made for cardiovascular risk assessment and measuring anti-Ro and anti-La antibodies in the peripartum period and conditional recommendations for osteoporosis and osteonecrosis. Two conditional recommendations were made for peripartum assessments, 1 for cervical cancer screening and 2 for hepatitis B and C screening. A strong recommendation was made for annual influenza vaccination.Conclusion.These are considered the first guidelines using the GRADE method for the monitoring of SLE. Existing evidence is largely of low to moderate quality, resulting in more conditional than strong recommendations. Additional rigorous studies and special attention to pediatric SLE populations and patient preferences are needed.

Sign in / Sign up

Export Citation Format

Share Document