scholarly journals An investigation of the prevalence and significance of gastric parietal-cell autoantibody in rheumatoid arthritis.

1967 ◽  
Vol 26 (6) ◽  
pp. 499-505
Author(s):  
E M Armstrong
2019 ◽  
Vol 118 (10) ◽  
pp. 1401-1407 ◽  
Author(s):  
Chun-Pin Chiang ◽  
Julia Yu-Fong Chang ◽  
Yi-Ping Wang ◽  
Yang-Che Wu ◽  
Yu-Hsueh Wu ◽  
...  

2017 ◽  
Vol 152 (5) ◽  
pp. S418
Author(s):  
Yuki Hirata ◽  
Shinji Fukuda ◽  
Kazuhiko Yamada ◽  
Kazuhide Higuchi ◽  
Yuki I. Kawamura ◽  
...  

2017 ◽  
Vol 116 (8) ◽  
pp. 613-619 ◽  
Author(s):  
Hung-Pin Lin ◽  
Yu-Hsueh Wu ◽  
Yi-Ping Wang ◽  
Yang-Che Wu ◽  
Julia Yu-Fong Chang ◽  
...  

Author(s):  
John G. Forte ◽  
Joseph G. Duman ◽  
Nimesh J. Pathak ◽  
Kent L. Mcdonald

1993 ◽  
Vol 71 (3) ◽  
pp. 191-200 ◽  
Author(s):  
JOHN M. PETTITT ◽  
BAN-HOCK TOH ◽  
JUDY M. CALLAGHAN ◽  
PAUL A. GLEESON ◽  
IAN R. VAN DRIEL

2001 ◽  
Vol 281 (2) ◽  
pp. C407-C417 ◽  
Author(s):  
David A. Ammar ◽  
Phuong N. B. Nguyen ◽  
John G. Forte

Acid secretion by the gastric parietal cell is controlled through movement of vesicles containing the proton pump, the H+-K+-ATPase (HK). We have used latrunculin B (Lat B), which binds to monomeric actin, to investigate actin turnover in the stimulated parietal cell. In isolated gastric glands, relatively high concentrations of Lat B were required to inhibit acid accumulation (ED50∼70 μM). Cultured parietal cells stimulated in the presence of low Lat B (0.1–1 μM) have reduced lamellipodia formation and some aberrant punctate phalloidin-stained structures, but translocation of HK and vacuolar swelling appeared unaffected. High Lat B (10–50 μM) resulted in gross changes in actin organization (punctate phalloidin-stained structures throughout the cell and nucleus) and reduced translocation of HK and vacuolar swelling. Resting parietal cells treated with high Lat B showed minor effects on morphology and F-actin staining. If resting cells treated with high Lat B were washed immediately before stimulation, they exhibited a normal stimulated morphology. These data suggest distinct pools of parietal cell actin: a pool highly susceptible to Lat B primarily involved in motile function of cultured cells; and a Lat B-resistant pool, most likely microvillar filaments, that is essential for secretion. Furthermore, the stimulation process appears to accentuate the effects of Lat B, most likely through Lat B binding to monomer actin liberated by the turnover of the motile actin filament pool.


2020 ◽  
Vol 119 (1) ◽  
pp. 544-552 ◽  
Author(s):  
Chun-Pin Chiang ◽  
Yang-Che Wu ◽  
Julia Yu-Fong Chang ◽  
Yi-Ping Wang ◽  
Yu-Hsueh Wu ◽  
...  

2007 ◽  
Vol 329 (2) ◽  
pp. 313-320 ◽  
Author(s):  
Sören Schreiber ◽  
Désirée Garten ◽  
Thanh Hoa Nguyen ◽  
Manuela Konradt ◽  
Roland Bücker ◽  
...  

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