scholarly journals Aging changes of the optic nerve head in relation to open angle glaucoma

1997 ◽  
Vol 81 (10) ◽  
pp. 840-845 ◽  
Author(s):  
D F Garway-Heath ◽  
G Wollstein ◽  
R A Hitchings
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Open Angle Glaucoma ◽  
Open Angle

scholarly journals Choroidal microvasculature dropout is spatially associated with optic nerve head microvasculature loss in open-angle glaucoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Min Kyung Song ◽  
Joong Won Shin ◽  
Jin Yeong Lee ◽  
Ji Wook Hong ◽  
Michael S. Kook
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence Tomography Angiography ◽  
Open Angle Glaucoma ◽  
Spatial Relationship ◽  
Vascular Supply ◽  
Open Angle ◽  
Regression Analyses ◽  
Angular Extent ◽  
Choroidal Vessels

AbstractThe presence of parapapillary choroidal microvasculature dropout (CMvD) may affect optic nerve head (ONH) perfusion in glaucoma patients, since parapapillary choroidal vessels provide vascular supply to the neighboring ONH. However, it remains to be determined whether the presence of parapapillary CMvD is associated with diminished perfusion in the nearby ONH. The present study investigated the spatial relationship between CMvD and ONH vessel density (ONH-VD) loss in open-angle glaucoma (OAG) eyes using optical coherence tomography angiography (OCT-A). This study included 48 OAG eyes with a single localized CMvD confined to the inferotemporal parapapillary sector and 48 OAG eyes without CMvD, matched for demographic and ocular characteristics. Global and regional ONH-VD values were compared between eyes with and without CMvD. The relationships between ONH-VD outcomes and clinical variables were assessed. ONH-VDs at the inferotemporal ONH sectors corresponding to the CMvD location were significantly lower in eyes with compared to those without CMvD. Multivariable linear regression analyses indicated that a lower inferotemporal ONH-VD was independently associated with CMvD presence and a greater CMvD angular extent (both P < 0.05). The localized presence of parapapillary CMvD in OAG eyes is significantly associated with ONH-VD loss in the neighboring ONH location, with a spatial correlation.

Blood circulation and morphology of optic nerve head in primary open-angle glaucoma

2000 ◽  
Vol 78 (S232) ◽  
pp. 40-40
Author(s):  
M. Ciancaglini ◽  
P. Carpineto ◽  
G. Falconio ◽  
S. Scaramucci ◽  
G. C. Nicola ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Blood Circulation ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle

scholarly journals Pit-like changes of the optic nerve head in open-angle glaucoma.

1978 ◽  
Vol 62 (6) ◽  
pp. 389-393 ◽  
Author(s):  
R. L. Radius ◽  
A. E. Maumenee ◽  
W. R. Green
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Open Angle Glaucoma ◽  
Open Angle

scholarly journals Assessment of the development of primary open-angle glaucoma and diabetic retinopathy using digital medicine

2020 ◽  
Vol 224 ◽  
pp. 03022
Author(s):  
I V Vorobyeva
Keyword(s):  
Diabetic Retinopathy ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Primary Open Angle Glaucoma ◽  
Low Vision ◽  
Open Angle Glaucoma ◽  
Digital Data ◽  
Open Angle ◽  
Neuroretinal Rim ◽  
Digital Medicine

The leading place in the structure of blindness and low vision is occupied by two diseases: primary open-angle glaucoma and diabetic retinopathy. The combination of two diseases in one eye gives an even more severe prognosis for vision. Modern diagnostic equipment helps in accurate and early diagnosis of the disease by analyzing digital data of the optic nerve head and macular area of the retina according to the results of an optical coherence tomograph. A mathematical model for predicting the development of diabetic retinopathy and primary open-angle glaucoma according to the proposed mathematical criteria has been developed. The criteria represent the ratio of the integral area of the neuroretinal rim to the integral volume of the neuroretinal rim; the retinal thickness criterion and criterion of the primary open-angle glaucoma and diabetic retinopathy are calculated. A computer program has been developed. The algorithm of the program, which includes windows for entering digital data of the macular zone and parameters of the optic nerve head, is presented. The result of the program is the statement of the risk of developing combined pathology of the fundus in a particular patient.

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