Focal choroidal excavation: review of literature

2020 ◽  
pp. bjophthalmol-2020-316992 ◽  
Author(s):  
Saurabh Verma ◽  
Vinod Kumar ◽  
Shorya Azad ◽  
Amber Amar Bhayana ◽  
Abhidnya Surve ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Differential Diagnosis ◽  
Polypoidal Choroidal Vasculopathy ◽  
Review Article ◽  
Choroidal Neovascularisation ◽  
Optical Coherence ◽  
Review Of Literature ◽  
Focal Choroidal Excavation ◽  
The Impact ◽  
Choroidal Vasculopathy

Focal choroidal excavation (FCE) is defined as an area of concavity in choroid detected on optical coherence tomography. These are mostly present in macular region without evidence of accompanying scleral ectasia or posterior staphyloma. Though initially considered to be congenital, increasing number of cases have been identified in association with other choroidal pathologies such as central serous choroidopathy, choroidal neovascularisation, polypoidal choroidal vasculopathy, choroiditis, choroidal tumours. In this review article, we aim to elaborate on the morphology, pathogenesis and differential diagnosis of FCE and specifically discuss the spectrum of diseases with known association along with the impact of their treatment on FCE

scholarly journals Polypoidal Choroidal Vasculopathy in Congolese Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Nelly N. Kabedi ◽  
David L. Kayembe ◽  
Gloria M. Elongo ◽  
Jean-Claude Mwanza
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Polypoidal Choroidal Vasculopathy ◽  
Indocyanine Green Angiography ◽  
Clinical Presentation ◽  
Case Series ◽  
Systemic Hypertension ◽  
Optical Coherence ◽  
Blurred Vision ◽  
Choroidal Vasculopathy

Purpose. Polypoidal choroidal vasculopathy (PCV) is a visually debilitating disease that mostly affects people of African and Asian heritage. Indocyanine green angiography (ICGA) is the recommended exploratory method for definitive diagnosis. The disease has been extensively described in Asians and Caucasians, but not in Africans. This study was conducted to document the clinical presentation and optical coherence tomography features of polypoidal choroidal vasculopathy (PCV) in Congolese patients. Methods. A prospective case series of patients with PCV was performed between January 2017 and June 2019. Routine ocular examination was performed including best corrected visual acuity measurement, slit-lamp examination, dilated direct fundoscopy, and spectral domain optical coherence tomography (OCT). The diagnosis was based on a combination of clinical and OCT signs. Results. Fourteen patients were diagnosed with PCV during this period. The average age was 64.7 ± 6.9 years. There were 8 females. Ten (71.4%) patients had systemic hypertension. Most patients (n = 9, 64.3%) had bilateral involvement. Blurred vision was the most common complaint (71.4%). The main clinical presentation was subretinal exudates, seen in 19 (82.6%) eyes of 11 (78.6%) patients and subretinal hemorrhage in 10 (43.5%) eyes. Macular localization was found in 16 eyes (69.5%) of 12 (85.7%) patients. Drusen were observed in 35.7% of the patients. On OCT imaging, thumb-like pigment epithelial detachment and subretinal exudation were the most frequent features, observed in 92.9% and 71.4% of the patients, respectively. Conclusions. PCV in Congolese patients showed features that are more similar to those observed in Caucasians. In this setting where indocyanine green angiography is not available, OCT facilitates the diagnosis of PCV.

IMPROVED VISUALIZATION OF POLYPOIDAL CHOROIDAL VASCULOPATHY LESIONS USING SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Retina ◽  
2009 ◽  
Vol 29 (1) ◽  
pp. 52-59 ◽  
Author(s):  
YUMIKO OJIMA ◽  
MASANORI HANGAI ◽  
ATSUSHI SAKAMOTO ◽  
AKITAKA TSUJIKAWA ◽  
ATSUSHI OTANI ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Polypoidal Choroidal Vasculopathy ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Choroidal Vasculopathy

scholarly journals Sensitivity, Specificity, and Limitations of Optical Coherence Tomography Angiography in Diagnosis of Polypoidal Choroidal Vasculopathy

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Yi-Ming Huang ◽  
Ming-Hung Hsieh ◽  
An-Fei Li ◽  
Shih-Jen Chen
Keyword(s):  
Optical Coherence Tomography ◽  
Sensitivity And Specificity ◽  
Polypoidal Choroidal Vasculopathy ◽  
Optical Coherence Tomography Angiography ◽  
False Positive Rate ◽  
Correct Diagnosis ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Choroidal Vasculopathy

Purpose. To evaluate the sensitivity and specificity of optical coherence tomography angiography (OCTA) in differentiating polypoidal choroidal vasculopathy (PCV) from age-related macular degeneration (AMD). Methods. Fundus color photographs, spectral-domain optical coherence tomography, and fluorescein angiography (step 1) and OCTA (step 2) of 50 eyes that had PCV or AMD were presented to two ophthalmologists. The final diagnoses of PCV were masked. Sensitivity and specificity were calculated and compared to the 2-step approach (before and after OCTA) in detecting PCV. The limitations were also evaluated. Results. Of the 50 eyes, 31 were PCV and 19 were non-PCV. The sensitivity increased from 69.5% to 90% after OCTA; however, there was no significant improvement in specificity after OCTA. 70.9% of the eyes with PCV had clear or obvious branching vascular nets (BVNs) in OCTA with high sensitivity (97.5%) after OCTA. Contrarily, 29.1% had insignificant BVNs with a low sensitivity (72.5%) after OCTA. 27% of the occult choroidal neovascularization (CNV) cases were overdiagnosed as PCV when OCTA was applied. Conclusions. OCTA based on clear BVNs at the choroidal level increased sensitivity of diagnosis of PCV by 20%. However, the false-positive rate also increased in occult CNV. Several limitations for a correct diagnosis of PCV were noted.

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