GW24-e0505 Direct comparison of SW-CG-HYPR and conventional SR-Turbo-FLASH myocardial perfusion MRI for detection of coronary artery disease

Heart ◽  
2013 ◽  
Vol 99 (Suppl 3) ◽  
pp. A151.1-A151
Author(s):  
Yang Jun ◽  
Heng Ma ◽  
Yanyan Jing ◽  
Jing Liu ◽  
Lan Ge ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Perfusion Mri ◽  
Artery Disease

Abstract 4174: Adenosine-Stress CT Myocardial Perfusion Imaging: Comparison with Stress Myocardial Perfusion MRI in Patients with Coronary Artery Disease

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Masaki Ishida ◽  
Hajime Sakuma ◽  
Shingo Kato ◽  
Motonori Nagata ◽  
Nanaka Ishida ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Myocardial Ischemia ◽  
Perfusion Ct ◽  
Perfusion Mri ◽  
Adenosine Stress ◽  
Stress Perfusion ◽  
Stress Myocardial Perfusion ◽  
Artery Disease

Background: CT coronary angiography with vasodilator stress might be of great value in detecting both myocardial ischemia and morphological stenoses of the coronary arteries. Stress myocardial perfusion MRI has been shown to provide accurate assessment of presence and extent of myocardial ischemia in patients with coronary artery disease(CAD). The aim of this study was to determine the value of stress myocardial perfusion CT for the detection of myocardial ischemia by using stress perfusion MRI as a reference method. Methods: The study protocol was approved by the institutional review board and all participants gave written informed consent. Cardiac CT was performed in 12 patients with suspected CAD by using a 64-detector MDCT scanner. Beta-blocker was orally administered prior to CT study. During continuous injection of adenosine, contrast enhanced CT images of the heart were acquired with retrospectively gated helical CT protocol. Adenosine stress myocardial perfusion MRI was performed within 2 weeks from CT perfusion study in all patients. Stress myocardial perfusion MDCT and MR images were qualitatively assessed by two observers using a 16-segment model. Results: All patients completed stress CT study protocol without significant side-effect. Averaged heart rate was 62+/−10 beats/min in the baseline state and 74+/−14 beats/min during adenosine stress. Perfusion abnormality during stress was observed in 83 (43.2%) of 192 segments by MDCT and in 89 (46.4%) of 192 segments by MRI. On a vessel based analysis, stress CT and stress MRI findings are concordant in 30 (83.3%) of 36 territories. The sensitivity, specificity and accuracy of adenosine stress myocardial perfusion CT for the predicting abnormal perfusion on stress perfusion MRI was 84.6%, 80% and 83.3%, respectively. Conclusion: Adenosine stress myocardial perfusion CT can be successfully performed in patients with CAD. Excellent agreement between stress myocardial perfusion CT and MRI observed in this study indicates the value of stress CT approach for comprehensive assessment of morphology and functional significance of CAD.

scholarly journals Diagnostic accuracy of stress myocardial perfusion MRI and late gadolinium-enhanced MRI for detecting flow-limiting coronary artery disease: a multicenter study

2008 ◽  
Vol 18 (12) ◽  
pp. 2808-2816 ◽  
Author(s):  
Kakuya Kitagawa ◽  
Hajime Sakuma ◽  
Motonori Nagata ◽  
Shigeo Okuda ◽  
Masaharu Hirano ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Diagnostic Accuracy ◽  
Multicenter Study ◽  
Perfusion Mri ◽  
Stress Myocardial Perfusion ◽  
Enhanced Mri ◽  
Artery Disease

scholarly journals Myocardial perfusion MRI using SW-CG-HYPR for the detection of coronary artery disease

2012 ◽  
Vol 14 (S1) ◽  
Author(s):  
Jun Yang ◽  
Heng Ma ◽  
Jing Liu ◽  
Lan Ge ◽  
David Chen ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Perfusion Mri ◽  
Artery Disease

scholarly journals Whole-Heart Dipyridamole Stress First-Pass Myocardial Perfusion MRI for the Detection of Coronary Artery Disease

2004 ◽  
Vol 45 (3) ◽  
pp. 475-486 ◽  
Author(s):  
Bonpei Takase ◽  
Masayoshi Nagata ◽  
Teruyoshi Kihara ◽  
Akira Kameyawa ◽  
Kumiko Noya ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Perfusion Mri ◽  
First Pass ◽  
Artery Disease ◽  
Whole Heart ◽  
Dipyridamole Stress

Stress-induced Myocardial Ischaemia – Perfusion Contrast Echocardiography to Evaluate Presence and Severity of Coronary Artery Disease

2011 ◽  
Vol 7 (3) ◽  
pp. 172
Author(s):  
Benoy Nalin Shah ◽  
Roxy Senior ◽  
◽  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Contrast Echocardiography ◽  
Evidence Base ◽  
Suspected Coronary Artery Disease ◽  
Ultrasound Contrast Agents ◽  
Prognostic Information ◽  
Non Invasive ◽  
Artery Disease

The development of stable transpulmonary ultrasound contrast agents (UCAs) has allowed the echocardiographic assessment of myocardial perfusion, a technique known as myocardial contrast echocardiography (MCE). MCE exploits the ultrasonic properties of UCAs, which consist of acoustically active gas-filled microspheres. These are intravascular agents that have a rheology similar to red blood cells and thus allow analysis of myocardial blood flow both at rest and after stress. The combined assessment of wall motion and myocardial perfusion provides significant diagnostic and prognostic information during stress echocardiography. Functional imaging tests, such as myocardial perfusion scintigraphy and stress cardiac magnetic resonance imaging, are also used for non-invasive assessment of coronary disease. The principal advantages of MCE are that it does not expose the patient to ionising radiation or radioactive pharmaceuticals, is not contraindicated in patients with an implanted metallic device or who suffer from claustrophobia and it can be performed at the bedside. The purpose of this article is to outline the physiological principles underpinning ischaemia testing with MCE before proceeding to review the evidence base for MCE in patients with known or suspected coronary artery disease.

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