Coronary anatomy in children with bicuspid aortic valves and associated congenital heart disease

Heart ◽  
2017 ◽  
Vol 104 (5) ◽  
pp. 385-393 ◽  
Author(s):  
Wilke M C Koenraadt ◽  
Margot M Bartelings ◽  
Regina Bökenkamp ◽  
Adriana C Gittenberger-de Groot ◽  
Marco C DeRuiter ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Arteries ◽  
Congenital Heart ◽  
Outflow Tract ◽  
Complex Congenital Heart Disease ◽  
Coronary Anatomy ◽  
Perimembranous Ventricular Septal Defect ◽  
Clinical Awareness

ObjectiveIn patients with bicuspid aortic valve (BAV), coronary anatomy is variable. High take-off coronary arteries have been described, but data are scarce, especially when associated with complex congenital heart disease (CHD). The purpose of this study was to describe coronary patterns in these patients.MethodsIn 84 postmortem heart specimens with BAV and associated CHD, position and height of the coronary ostia were studied and related to BAV morphology.ResultsHigh take-off right (RCA) and left coronary arteries (LCA) were observed in 23% and 37% of hearts, respectively, most frequently in hearts with hypoplastic left ventricle (HLV) and outflow tract anomalies. In HLV, high take-off was observed in 18/40 (45%) more frequently of LCA (n=14) than RCA (n=6). In hearts with aortic hypoplasia, 8/13 (62%) had high take-off LCA and 6/13 (46%) high take-off RCA. High take-off was seen 19 times in 22 specimens with perimembranous ventricular septal defect (RCA 8, LCA 11). High take-off was associated with type 1A BAV (raphe between right and left coronary leaflets), more outspoken for the RCA. Separate ostia of left anterior descending coronary artery and left circumflex coronary artery were seen in four hearts (5%), not related to specific BAV morphology.ConclusionHigh take-off coronary arteries, especially the LCA, occur more frequently in BAV with associated CHD than reported in normal hearts and isolated BAV. Outflow tract defects and HLV are associated with type 1A BAV and high take-off coronary arteries. Although it is unclear whether these findings in infants with detrimental outcome can be related to surviving adults, clinical awareness of variations in coronary anatomy is warranted.

scholarly journals Comorbidity as a mediator of depression in adults with congenital heart disease: A population-based cohort study

2020 ◽  
pp. 147451512092378
Author(s):  
Hsiao-Ling Yang ◽  
Nien-Tzu Chang ◽  
Jou-Kou Wang ◽  
Chun-Wei Lu ◽  
Yong-Chen Huang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Complex Congenital Heart Disease ◽  
Chronic Obstructive ◽  
Adult Congenital ◽  
Artery Disease

Background The population of adults with congenital heart disease (CHD) has increased dramatically with a high prevalence of acquired cardiac and non-cardiac comorbidities. However, the relationship among congenital heart disease, physical comorbidities, and psychological health in this population is not well studied. Aims The purpose of this study was to investigate (a) the association between adult congenital heart disease and the occurrence of depression and (b) whether physical comorbidities mediated the association between congenital heart disease and the occurrence of depression. Methods This retrospective cohort study was followed from 1 January 2010–31 December 2013, based on the data from the National Health Insurance Research Database 2010 in Taiwan. We used mediation analysis in survival data to assess the mediated effect. The hazard ratios were adjusted by age, sex, area of residence, and estimated propensity scores. Results We recruited 2122 adult congenital heart disease patients and 8488 matched controls. Nearly half of patients diagnosed with simple congenital heart disease, 39.0% had complex congenital heart disease, and 11.2% had unclassified congenital heart disease. Adult congenital heart disease patients had a significantly higher risk of depression than matched controls (adjusted hazard ratio = 1.43 and 1.48, for all and complex congenital heart disease, respectively, p<0.05). Coronary artery disease and chronic obstructive pulmonary disease were the significant comorbidities mediating the relationship between adult congenital heart disease and depression, the proportions mediated by coronary artery disease or chronic obstructive pulmonary disease were 35.5% and 12.9%, respectively. Conclusions Helping patients to prevent psychological and physical acquired disease is imperative. Coronary artery disease is a potent mediator between congenital heart disease and depression, especially for patients with complex congenital heart disease.

scholarly journals Transcatheter Closure of Saccular Coronary Artery Fistula

2015 ◽  
Vol 5 (1) ◽  
pp. 41-45
Author(s):  
Saud A. Bahaidarah ◽  
Jameel Al-Ata
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Case Report ◽  
Coronary Artery ◽  
Coronary Arteries ◽  
Congenital Heart ◽  
Transcatheter Closure ◽  
Coronary Artery Fistula ◽  
Rare Entity

Coronary artery fistula is a rare entity of congenital heart disease but is the most common anomaly of coronary arteries. This is a case report of a 22-years-old female diagnosed with coronary artery fistula that underwent transcatheter closure of saccular coronary artery fistula.

Surgical management of an anomalous right coronary artery

2016 ◽  
Vol 9 (8) ◽  
pp. NP1-NP2 ◽  
Author(s):  
Margaux Pontailler ◽  
Pierre Demondion ◽  
Guillaume Lebreton
Keyword(s):  
Congenital Heart Disease ◽  
Cardiac Arrest ◽  
Heart Disease ◽  
Coronary Artery ◽  
Sudden Death ◽  
Young Patient ◽  
Coronary Arteries ◽  
Right Coronary Artery ◽  
Congenital Heart ◽  
The Right

Anomalous aortic origin of coronary arteries is a rare congenital heart disease that can be associated with sudden death. We present the case of a young patient who sustained a cardiac arrest revealing an anomalous origin of the right coronary artery. Unroofing and pericardial enlargement of the coronary artery ostia was performed and the patient is actually asymptomatic.

scholarly journals Coronary Anatomy in Congenital Heart Disease: The Important Contributions of Professor Dr. Adriana Gittenberger-de Groot

2021 ◽  
Vol 8 (3) ◽  
pp. 27
Author(s):  
Mark Hazekamp
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Congenital Heart ◽  
Coronary Anatomy ◽  
Cardiac Surgeon

The contributions of Professor Dr. Adriana Gittenberger-de Groot in relation to coronary artery development and classification are described from the viewpoint of a pediatric cardiac surgeon.

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