Pernicious Anaemia and Polycythaemia Vera: A Case Report

Vitamin B12 deficiency usually presents with megaloblastic anemia, pancytopenia, and neurological symptoms. The cause is usually, nutritional deficiency, increase demand, decrease absorption. This report describes a case with symptoms of apathy and findings suggestive of severe hemolytic anemia, diagnosed with vitamin B12 deficiency. Haemolysis is a rare hematological finding in cases of B12 deficiency, and descriptions of a nutritional vitamin B12 deficiency, without evidence of pernicious anaemia, causing haemolysis, are even scarcer, and this paper was intended to draw physicians’ attention to this rare form of presentation.

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Severe encephalopathy with epilepsy in an infant caused by subclinical maternal pernicious anaemia: case report and review of the literature

European Journal of Pediatrics ◽

10.1007/s00431-004-1402-4 ◽

2004 ◽

Vol 163 (4-5) ◽

pp. 196-201 ◽

Cited By ~ 46

Author(s):

G. Christoph Korenke ◽

Donald H. Hunneman ◽

Stefan Eber ◽

Folker Hanefeld

Keyword(s):

Case Report ◽

Pernicious Anaemia ◽

Review Of The Literature

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Hydroxycarbamide associated platelet count oscillations in a patient with polycythaemia vera. A case report and review of the literature

Platelets ◽

10.1080/09537100701882053 ◽

2008 ◽

Vol 19 (3) ◽

pp. 234-235 ◽

Cited By ~ 3

Author(s):

John Burthem ◽

Mohammed Suhail Chaudhry

Keyword(s):

Platelet Count ◽

Case Report ◽

Polycythaemia Vera ◽

Review Of The Literature

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Gastric Secretory Function in Polycythaemia Vera

Scottish Medical Journal ◽

10.1177/003693306801301102 ◽

1968 ◽

Vol 13 (11) ◽

pp. 372-378 ◽

Cited By ~ 1

Author(s):

R. Hume ◽

J. F. Adams

Keyword(s):

Duodenal Ulcer ◽

Peptic Ulcer ◽

Acid Output ◽

Intrinsic Factor ◽

Pernicious Anaemia ◽

Polycythaemia Vera ◽

Secretory Function ◽

Maximal Acid Output

Maximal acid output (M.A.O.) and intrinsic factor (I.F.) of the stomach were measured in 16 patients with polycythaemia vera, 4 of whom had a duodenal ulcer and 2 pernicious anaemia. It was found that, in general, the M.A.O. was significantly less than normal unless an active duodenal ulcer was present when the M.A.O. would reach the usual levels for duodenal ulcer subjects. The gastric I.F. output showed a significant correlation with the M.A.O. These results are discussed in the light of the increased incidence of peptic ulcer in polycythaemia vera and the occasionally reported cases of polycythaemia vera and pernicious anaemia.

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