Effects of Siegesbeckia pubescens on Immediate Hypersensitivity Reaction

1997 ◽  
Vol 25 (02) ◽  
pp. 163-167 ◽  
Author(s):  
Hyung Min Kim
Keyword(s):  
Mast Cells ◽  
Hypersensitivity Reaction ◽  
Histamine Release ◽  
Immunoglobulin E ◽  
Immediate Hypersensitivity ◽  
Antiallergic Activity ◽  
Peritoneal Mast Cells ◽  
Ige Mediated ◽  
Rat Peritoneal Mast Cells ◽  
Siegesbeckia Pubescens

This study was carried out to examine the effect of an aqueous extract from Siegesbeckia pubescens (Compositae) (SPAE) on immunoglobulin E (IgE)-mediated immediate hypersensitivity reaction. Forty-eight hours passive cutaneous anaphylaxis in rats was significantly inhibited by oral administration of SPAE (100 μg/g). It also inhibited histamine release from rat peritoneal mast cells induced by anti-dinitrophenyl (DNP)-IgE and DNP-human serum albumin. The data indicate that SPAE has antiallergic activity, and that its action may be due to inhibition of histamine release from mast cells.

Platelet factor 4 fragment induces histamine release from rat peritoneal mast cells

Peptides ◽  
2002 ◽  
Vol 23 (10) ◽  
pp. 1713-1717 ◽  
Author(s):  
Ryujiro Suzuki ◽  
Tomoki Kimura ◽  
Kiyoyuki Kitaichi ◽  
Yasuaki Tatsumi ◽  
Miyoko Matsushima ◽  
...  
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Platelet Factor 4 ◽  
Platelet Factor ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells

scholarly journals Enzymatic Synthesis and Anti-Allergic Activities of Curcumin Oligosaccharides

2010 ◽  
Vol 3 ◽  
pp. BCI.S2768 ◽  
Author(s):  
Kei Shimoda ◽  
Hiroki Hamada
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Enzymatic Synthesis ◽  
Antibody Formation ◽  
Cyclodextrin Glucanotransferase ◽  
Enzymatic Method ◽  
Inhibitory Effects ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells ◽  
Suppressive Action

Curcumin 4‘- O-glucooligosaccharides were synthesized by a two step-enzymatic method using almond β-glucosidase and cyclodextrin glucanotransferase (CGTase). Curcumin was glucosylated to curcumin 4‘- O-β-D-glucopyranoside by almond β-glucosidase in 19% yield. Curcumin 4‘- O-β-D-glucopyranoside was converted into curcumin 4‘- O-β-glucooligosaccharides, i.e. 4‘- O-β-maltoside (51%) and 4‘- O-β-maltotrioside (25%), by further CGTase-catalyzed glycosylation. Curcumin 4‘- O-β-glycosides showed suppressive action on IgE antibody formation and inhibitory effects on histamine release from rat peritoneal mast cells.

Enhancement of Histamine Release from Rat Peritoneal Mast Cells Exposed to Formaldehyde

1992 ◽  
Vol 4 (2) ◽  
pp. 125-136 ◽  
Author(s):  
Hidekazu Fujimaki ◽  
Fujio Shiraishi ◽  
Noboru Katayama
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells
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