Enzymatic Synthesis and Anti-Allergic Activities of Curcumin Oligosaccharides
Keyword(s):
Curcumin 4‘- O-glucooligosaccharides were synthesized by a two step-enzymatic method using almond β-glucosidase and cyclodextrin glucanotransferase (CGTase). Curcumin was glucosylated to curcumin 4‘- O-β-D-glucopyranoside by almond β-glucosidase in 19% yield. Curcumin 4‘- O-β-D-glucopyranoside was converted into curcumin 4‘- O-β-glucooligosaccharides, i.e. 4‘- O-β-maltoside (51%) and 4‘- O-β-maltotrioside (25%), by further CGTase-catalyzed glycosylation. Curcumin 4‘- O-β-glycosides showed suppressive action on IgE antibody formation and inhibitory effects on histamine release from rat peritoneal mast cells.
1991 ◽
Vol 57
(1)
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pp. 79-90
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1994 ◽
Vol 64
(1)
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pp. 1-8
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1984 ◽
Vol 32
(12)
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pp. 5051-5054
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1987 ◽
Vol 83
(4)
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pp. 348-353
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Keyword(s):
Inhibitory effects of tannins on superoxide-induced histamine release from rat peritoneal mast cells
1995 ◽
Vol 106
(supplement)
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pp. 207-211
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1985 ◽
Vol 33
(2)
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pp. 690-696
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1994 ◽
Vol 42
(3)
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pp. 570-575
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