An efficient method for oxygen diffusion in a spherical cell with nonlinear oxygen uptake kinetics

Author(s):  
Soner Aydinlik

In this paper, a novel numerical technique, the first-order Smooth Composite Chebyshev Finite Difference method, is presented. Imposing a first-order smoothness of the approximation polynomial at the ends of each subinterval is originality of the method. Both round-off and truncation error analyses of the method are performed beside the convergence analysis. Diffusion of oxygen in a spherical cell including nonlinear uptake kinetics is solved by using the method. The obtained results are compared with the existing methods in the literature and it is observed that the proposed method gives more reliable results.

2021 ◽  
Vol 87 (2) ◽  
pp. 463-467
Author(s):  
Soner Aydinlik ◽  
◽  
Ahmet Kirisb

A new effective technique based on Chebyshev Finite Difference Method is introduced. First order smoothness of the approximation polynomial at the end points of each sub-interval is imposed in addition to the continuity condition. Both round-off and truncation error analyses are given besides the convergence analysis. Coupled Lane Emden boundary value problem in Catalytic Diffusion Reactions is investigated by using presented method. The obtained results are compared with the existing methods in the literature and it is observed that the proposed method gives more reliable results than the others.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
M. A. Sandoval-Hernandez ◽  
H. Vazquez-Leal ◽  
A. Sarmiento-Reyes ◽  
U. Filobello-Nino ◽  
F. Castro-Gonzalez ◽  
...  

This work presents the application of homotopy perturbation method (HPM) and Optimized Direct Padé (ODP) to obtain a handy and easily computable approximate solution of the nonlinear differential equation to model the oxygen diffusion in a spherical cell with nonlinear oxygen uptake kinetics. On one hand, the obtained HPM solution is fully symbolic in terms of the coefficients of the equation, allowing us to use the same solution for different values of the maximum reaction rate, the Michaelis constant, and the permeability of the cell membrane. On the other hand, the numerical experiments show the high accuracy of the proposed ODP solution, resulting in 3.58×10-4 as the lowest absolute relative error (A.R.E.) for a set of coefficients. In addition, a novel technique is proposed to reduce the number of algebraic operations during the process of application of ODP method through the use of the Taylor series, which help to simplify the algebraic expressions used. The powerful process to obtain the solution shows that the Optimized Direct Padé and homotopy perturbation method are suitable methods to use.


2014 ◽  
Vol 07 (02) ◽  
pp. 1450020 ◽  
Author(s):  
Randolph Rach ◽  
Abdul-Majid Wazwaz ◽  
Jun-Sheng Duan

In this paper, we investigate the diffusion of oxygen in a spherical cell including nonlinear uptake kinetics. The Lane–Emden boundary value problem with Michaelis–Menten kinetics is used to model the dimensionless oxygen concentration in our analysis. We first convert the Lane–Emden equation to the equivalent Volterra integral form that incorporates the boundary condition at the cell's center, but which still leaves one unknown constant of integration, as an intermediate step. Next we evaluate the Volterra integral form of the concentration and its flux at the cell membrane and substitute them into the remaining boundary condition to determine the unknown constant of integration by appropriate algebraic manipulations. Upon substitution we have converted the equivalent Volterra integral form to the equivalent Fredholm–Volterra integral form, and use the Duan–Rach modified recursion scheme to effectively decompose the unknown constant of integration by formula. The Adomian decomposition method is then applied to solve the equivalent nonlinear Fredholm–Volterra integral representation of the Lane–Emden model for the concentration of oxygen within the spherical cell. Our approach shows enhancements over existing techniques.


2015 ◽  
Vol 4 (2) ◽  
pp. 253 ◽  
Author(s):  
Hector Vazquez-Leal ◽  
Mario Sandoval-Hernandez ◽  
Roberto Castaneda-Sheissa ◽  
Uriel Filobello-Nino ◽  
Arturo Sarmiento-Reyes

2003 ◽  
Vol 21 (1) ◽  
pp. 39-47 ◽  
Author(s):  
ALFREDO SANTALLA ◽  
MARGARITA PÉREZ ◽  
MANUEL MONTILLA ◽  
LÁZARO VICENTE ◽  
RICHARD DAVISON ◽  
...  

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