Spindle Cell Carcinoma of the Breast

2021 ◽  
Author(s):  
Jeffrey Landy ◽  
Suzanne A. Pascarella, DO ◽  
Annina N. Wilkes, MD ◽  
Christopher Sebastiano
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Yukiko Tokuda ◽  
Eun Sook Ko ◽  
Masahiro Yanagawa ◽  
Keiichiro Honma ◽  
Kenzo Shimazu ◽  
...  

2012 ◽  
Vol 33 (3) ◽  
pp. 115-119 ◽  
Author(s):  
Zeina Nahleh ◽  
Vivian Ebrahim ◽  
Rose Guerrero ◽  
Sumit Gaur ◽  
Anoop Ayyappan ◽  
...  

2019 ◽  
Vol 30 ◽  
pp. iii19 ◽  
Author(s):  
Z. Gatalica ◽  
S. Vranic ◽  
P. Stafford ◽  
J. Palazzo ◽  
F. Skenderi ◽  
...  

Rare Tumors ◽  
2020 ◽  
Vol 12 ◽  
pp. 203636132097702 ◽  
Author(s):  
April Choi ◽  
Philip M Carpenter ◽  
Shefali Chopra ◽  
Kristi M Lara ◽  
William W Tseng ◽  
...  

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.


2015 ◽  
Vol 139 (4) ◽  
pp. 552-557 ◽  
Author(s):  
Jessica B. Dwyer ◽  
Beth Z. Clark

Low-grade fibromatosis-like spindle cell carcinoma is a rare tumor in the breast, and represents a variant of the very heterogeneous group of metaplastic carcinomas of the breast. These tumors warrant distinction because of their resemblance to pure fibromatosis, their propensity for local recurrence, and their favorable prognosis among the metaplastic carcinomas of the breast. The diagnosis is potentially challenging, particularly on core needle biopsies, because of the morphologic overlap with other low-grade spindle cell lesions. Recognition of a proliferation of cytologically bland spindle cells with areas of epithelial differentiation in combination with immunohistochemistry using antibodies against cytokeratins and myoepithelial markers should aid in producing a definitive diagnosis. These tumors can be locally aggressive with an increased incidence of local recurrence, but the potential for lymph node or distant metastasis is low. Complete excision with adequate margins is considered curative in the majority of cases.


Author(s):  
Takahiro INAISHI ◽  
Arihiro SHIBATA ◽  
Daishi MORIMOTO ◽  
Naohiro NOMURA ◽  
Tsunenobu TAKASE ◽  
...  

2015 ◽  
Vol 76 (9) ◽  
pp. 2111-2115
Author(s):  
Maki TAKAI ◽  
Kohjiro MASHINO ◽  
Miwa NODA ◽  
Hideya TASHIRO ◽  
Junpei WADA ◽  
...  

Author(s):  
Seiya SUSUMU ◽  
Norihiro KOHARA ◽  
Jyunpei MAEDA ◽  
Akimi MIYATA ◽  
Minoru AMANO ◽  
...  

1986 ◽  
Vol 32 (3) ◽  
pp. 189-192 ◽  
Author(s):  
Robert Sheridan ◽  
Sandy Robbins ◽  
Juan C. D'Avis ◽  
George J. Collins

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