scholarly journals Neuromyelitis Optica Spectrum Disorders: Spectrum of MR Imaging Findings and Their Differential Diagnosis

Radiographics ◽  
2018 ◽  
Vol 38 (1) ◽  
pp. 169-193 ◽  
Author(s):  
Bruna Garbugio Dutra ◽  
Antônio José da Rocha ◽  
Renato Hoffmann Nunes ◽  
Antônio Carlos Martins Maia
Radiographics ◽  
2018 ◽  
Vol 38 (2) ◽  
pp. 662-662 ◽  
Author(s):  
Bruna Garbugio Dutra ◽  
Antônio José da Rocha ◽  
Renato Hoffmann Nunes ◽  
Antônio Carlos Martins Maia Júnior

2014 ◽  
Vol 21 (4) ◽  
pp. 488-491 ◽  
Author(s):  
Shanthi Viswanathan

We report two cases of neuromyelitis optica spectrum disorder with hypoglossal nerve involvement resulting in a wasted tongue associated with other brainstem symptoms of hypogeusia, hypersalivation, hiccough, increased sweating, hyperemesis and myelitis (in the second patient). This occurred due to involvement of the hypoglossal, tractus solitarius and dorsal vagal nuclei. Though the myelitis and other brainstem signs recovered the hypoglossal nerve involvement resulting in a unilateral wasted tongue did not. It is important to consider neuromyelitis optica and its spectrum disorders in the differential diagnosis of a wasted tongue though its occurrence is rare.


2011 ◽  
Vol 18 (7) ◽  
pp. 1050-1053 ◽  
Author(s):  
Piyush Banker ◽  
Smitha Sonni ◽  
Ilya Kister ◽  
John P Loh ◽  
Yvonne W Lui

AQP4 water channels are thought to be the target of autoimmune attack in neuromyelitis optica-spectrum disorders (NMOsd). AQP4 are highly expressed on ventricular ependyma. The objective of this study was to describe a novel pattern of linear, ‘pencil-thin’ enhancement of ventricular ependyma in NMOsd. We report two NMOsd patients with pencil-thin ependymal enhancement along the frontal and occipital horns of lateral ventricles. Differential diagnosis of ependymal enhancement should include NMOsd alongside with infectious and neoplastic etiologies. Pencil-thin ependymal enhancement may be a helpful radiological marker of NMOsd that can be used to differentiate this condition from multiple sclerosis.


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