Atrial Natriuretic Factor in Central Cardiovascular Control

Physiology ◽  
1993 ◽  
Vol 8 (5) ◽  
pp. 223-228 ◽  
Author(s):  
S Oparil ◽  
JM Wyss
Keyword(s):  
Atrial Natriuretic Factor ◽  
Spontaneously Hypertensive Rat ◽  
Brain Regions ◽  
Baroreceptor Reflex ◽  
Hypothalamic Area ◽  
Spontaneously Hypertensive ◽  
Natriuretic Factor ◽  
Effector System ◽  
Baroreceptor Reflex Sensitivity ◽  
Atrial Natriuretic

A complete atrial natriuretic factor (ANF) synthetic, processing, and effector system is found in rat brain. ANF in critical brain regions, including anterior hypothalamic area and nucleus tractus solitarii, contributes importantly to the tonic control of blood pressure, sympathetic outflow, and baroreceptor reflex sensitivity in the spontaneously hypertensive rat.

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