scholarly journals Solid and Cystic Tumor (SCT) of the Pancreas in an Adult Man

HPB Surgery ◽  
1997 ◽  
Vol 10 (5) ◽  
pp. 315-321 ◽  
Author(s):  
K. Ohiwa ◽  
M. Igarashi ◽  
N. Nagasue ◽  
M. Nagasaki ◽  
T. Harada
Keyword(s):  
Tumor Cells ◽  
Neuron Specific Enolase ◽  
Cystic Tumor ◽  
Pancreatic Hormones ◽  
Zymogen Granules ◽  
Silver Stain ◽  
Head Of The Pancreas ◽  
Solid And Cystic Tumor ◽  
Upper Abdominal ◽  
Cut Surface

Solid and cystic tumor (SCT) of the pancreas predominantly Occurs in women, and the occurrence in men is extremely rare. We experienced a male case of SCT. A 38-year-old man was admitted with the complaint of upper abdominal pain. CT scan showed the presence of a mass in the head of the pancreas. The mass was composed of high density areas and low density areas. Ultrasonograms revealed the mass being composed of high echoic areas and low echoic areas. The mass .was hypovascular on angiography. SCT was suspected and pancreaticoduodenectomy was performed. The cut surface of the tumor showed mainly cystic degenerative areas containing dark red hemorrhagic materials. Microscopically, there were solid areas in the periphery and pseudopapillary areas in the center. No metastasis was found in the removed lymph nodes. The tumor cells were not stained by Grimelius' silver stain. The tumor cells were positive for alpha-l-antitrypsin (AAT) and neuron-specific enolase (NSE). Pancreatic hormones such as insulin, glucagon, and somatostatin were all negative. Electron micrograph showed that tumor cells were rich in mitochondria. Zymogen granules and neurosecretory granules were not detected. Estrogen receptor (ER) and progesterone receptor (PR) were both negative.

scholarly journals Glial Fibrillary Acidic Protein (GFAP) in Oligodendrogliomas: A Reflection of Transient GFAP Expression by Immature Oligodendroglia

1986 ◽  
Vol 13 (4) ◽  
pp. 307-311 ◽  
Author(s):  
V. Jagadha ◽  
W.C. Halliday ◽  
L.E. Becker
Keyword(s):  
White Matter ◽  
Glial Fibrillary Acidic Protein ◽  
Tumor Cells ◽  
Intermediate Filaments ◽  
Intermediate Filament ◽  
Immunohistochemical Staining ◽  
Neuron Specific Enolase ◽  
Acidic Protein ◽  
Gfap Expression ◽  
S 100

ABSTRACT:Fourteen pure oligodendrogliomas were studied by light- and electronmicroscopy and immunohistochemistry to examine glial fibrillary acidic protein (GFAP) positivity in the tumors. To compare the immunohistochemical staining patterns of neoplastic oligodendroglia and immature oligodendroglia, myelination glia in the white matter of eight normal brains from children under 6 months of age were studied. The tumors possessed light microscopic and ultrastructural features characteristic of oligodendrogliomas. Microtubules were found in the cytoplasm of nine tumors on electronmicroscopy. In one, intermediate filaments and microtubules were observed in occasional tumor cells with polygonal crystalline structures in the cytoplasm. Using the peroxidase-antiperoxidase technique, all specimens were stained for GFAP, vimentin, S-100 and neuron-specific enolase (NSE). In nine tumors, variable numbers of cells with an oligodendroglial morphology reacted positively for GFAP. All tumors were positive for S-100 and negative for vimentin and NSE. The myelination glia in the eight normal brains stained positively for GFAP but not for vimentin. Vimentin is expressed by developing, reactive and neoplastic astrocytes. Thus, GFAP positivity combined with vimentin negativity in both neoplastic and immature oligodendroglia suggests that GFAP positivity in oligodendrogliomas may reflect the transient expression of this intermediate filament by immature oligodendroglia.

scholarly journals A SURGICAL CASE OF SOLID AND CYSTIC TUMOR OF THE PANCREAS

1995 ◽  
Vol 56 (8) ◽  
pp. 1671-1676
Author(s):  
Nobuyuki MUSHA ◽  
Yasuhiro SETSU ◽  
Masahide HIRATSUKA ◽  
Akio KUSAMA ◽  
Muneharu NAKAYAMA ◽  
...  
Keyword(s):  
Cystic Tumor ◽  
Surgical Case ◽  
Solid And Cystic Tumor

scholarly journals An Operated Case of Solid and Cystic Tumor of the Pancreas and 189 Cases Review of Litereture in Japan

1997 ◽  
Vol 50 (0) ◽  
pp. 322-323
Author(s):  
Hiroshi Yana ◽  
Mitsuhiro Kida ◽  
Kouji Ono ◽  
Hiroshi Imaizumi ◽  
Yukihito Yamada ◽  
...  
Keyword(s):  
Cystic Tumor ◽  
Solid And Cystic Tumor

scholarly journals A case report of solid and cystic tumor of the pancreas.

1987 ◽  
Vol 20 (8) ◽  
pp. 1972-1975
Author(s):  
Yuichi MACHIKI ◽  
Yutaka OMURA ◽  
Daizo OHASHI ◽  
Isao IRITANI ◽  
Hirotoshi OGAWA ◽  
...  
Keyword(s):  
Case Report ◽  
Cystic Tumor ◽  
Solid And Cystic Tumor

scholarly journals An Operated Case of Nonfunctioning Islet Cell Tumor of the Pancreas which Resembled Solid and Cystic Tumor Found Unexpectedly at the Health Check

1998 ◽  
Vol 52 (0) ◽  
pp. 176-177
Author(s):  
Masao Araki ◽  
Mitsuhiro Kida ◽  
Maya Watanabe ◽  
Yoshiki Kida ◽  
Yukihito Yamada ◽  
...  
Keyword(s):  
Islet Cell ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Health Check ◽  
Cystic Tumor ◽  
Solid And Cystic Tumor ◽  
Nonfunctioning Islet Cell Tumor

Clinical, pathologic, and molecular spectrum of tumors associated with t(11;22)(p13;q12): desmoplastic small round-cell tumor and its variants.

1998 ◽  
Vol 16 (9) ◽  
pp. 3028-3036 ◽  
Author(s):  
W L Gerald ◽  
M Ladanyi ◽  
E de Alava ◽  
M Cuatrecasas ◽  
B H Kushner ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Abdominal Cavity ◽  
Neuron Specific Enolase ◽  
Chimeric Protein ◽  
Cell Tumor ◽  
Round Cell ◽  
Round Cell Tumor ◽  
Small Round Cell Tumor ◽  
Small Round Cell ◽  
Translocation Breakpoints

PURPOSE Intense investigation has reshaped concepts about undifferentiated tumors occurring in young people (small round-cell tumors). Tumors associated with t(11;22)(p13;q12) and descriptively designated desmoplastic small round-cell tumor (DSRCT) are a distinctive, rare, poorly understood member of this family. We reviewed 109 cases of DSRCT to further characterize this entity better. METHODS Clinical information and histology were reviewed. Immunohistochemistry and immunoblotting were performed using standard techniques. Chimeric EWS-WT1 RNA and DNA were detected by polymerase chain reaction (PCR) and genomic translocation breakpoints mapped in a subset of cases. RESULTS There were 90 males and 19 females from 6 to 49 years of age (mean, 22 years). A total of 103 had tumor in the abdominal cavity, four in the thoracic region, one in the posterior cranial fossa, and one in the hand. Typical histologic and immunohistochemical features were usually evident in well-sampled tumors, but variations in cellularity, stromal components, cytology, architecture, and immunoreactivity occurred. Tumor cells were usually reactive with antibodies to keratin (67 of 78 cases, 86%), epithelial membrane antigen (50 of 54, 93%), vimentin (64 of 66, 97%), desmin (70 of 78, 90%), neuron-specific enolase (60 of 74, 81%), and the EWS-WT1 chimeric protein (25 of 27, 93%); typically nonreactive for muscle common actin (one of 58, 2%), myogenin (zero of eight, 0%), and chromogranin (one of 46, 2%); and variably reactive for MIC2 (nine of 47, 20%) and p53 (five of 17 with > 20% tumor cells reactive). Functional EWS-WT1 gene fusion was evident in 25 of 26 cases with genomic breakpoints in WT1 intron 7, and EWS introns 7, 8, and 9. Prognosis in general is poor, but tumors are responsive to aggressive therapy. CONCLUSION This large review identifies a greater degree of clinical, pathologic, and molecular variation than originally appreciated for tumors associated with t(11;22)(p13;q12). Translocation and functional fusion of the EWS and WT1 genes appears to be a consistent feature of this unique tumor.

Solid and Cystic Tumor of the Pancreas

1991 ◽  
Vol 13 (2) ◽  
pp. 240
Author(s):  
&NA;
Keyword(s):  
Cystic Tumor ◽  
Solid And Cystic Tumor

Solid and cystic tumor of the pancreas in a 12-year-old boy

2003 ◽  
Vol 45 (3) ◽  
pp. 339-341 ◽  
Author(s):  
Takeshi Asano ◽  
Tae Matsumoto ◽  
Cai Ling Zhi ◽  
Miho Maeda ◽  
Eiji Uchida ◽  
...  
Keyword(s):  
Cystic Tumor ◽  
Solid And Cystic Tumor

Frantz's tumor (solid and cystic tumor of the pancreas) with liver metastasis: Successful treatment and long-term follow-up

1995 ◽  
Vol 30 (5) ◽  
pp. 724-726 ◽  
Author(s):  
Minoru Horisawa ◽  
Noriji Nijnomi ◽  
Taichiro Sato ◽  
Syunpei Yokoi ◽  
Koji Oda ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Successful Treatment ◽  
Cystic Tumor ◽  
Long Term Follow Up ◽  
Solid And Cystic Tumor
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