scholarly journals Inferior ST-Elevation Myocardial Infarction Associated with Takotsubo Cardiomyopathy

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Oliver Koeth ◽  
Uwe Zeymer ◽  
Rudolf Schiele ◽  
Ralf Zahn

Takotsubo cardiomyopathy (TCM) is usually characterized by transient left ventricular apical ballooning. Due to the clinical symptoms which include chest pain, electrocardiographic changes, and elevated myocardial markers, Takotsubo cardiomyopathy is frequently mimicking ST-elevation myocardial infarction in the absence of a significant coronary artery disease. Otherwise an acute occlusion of the left anterior descending coronary artery can produce a typical Takotsubo contraction pattern. ST-elevation myocardial infarction (STEMI) is frequently associated with emotional stress, but to date no cases of STEMI triggering TCM have been reported. We describe a case of a female patient with inferior ST-elevation myocardial infarction complicated by TCM.

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Jun Muratsu ◽  
Atsuyuki Morishima ◽  
Hiroyasu Ueda ◽  
Hisatoyo Hiraoka ◽  
Katsuhiko Sakaguchi

Takotsubo cardiomyopathy is a disorder characterized by left ventricular apical ballooning and electrocardiographic changes in the absence of coronary artery disease. While reversible in many cases, the mechanism of this disorder remains unclear. The most frequent clinical symptoms of takotsubo cardiomyopathy on admission are chest pain and dyspnea, resembling acute myocardial infarction. Here, we describe two cases of takotsubo cardiomyopathy without chest pain or dyspnea in patients on maintenance hemodialysis. The asymptomatic nature of these two cases may be due to the patients being on hemodialysis. Periodic electrocardiograms (ECG) may be helpful in screening this population for asymptomatic takotsubo cardiomyopathy and in evaluating its incidence.


2021 ◽  
Vol 14 (8) ◽  
pp. e243811
Author(s):  
Clara Green ◽  
Adnan Nadir ◽  
Will Lester ◽  
Davinder Dosanjh

COVID-19 is a prothrombotic condition that is also associated with raised troponin levels and myocardial damage. We present a case of a 54-year-old man who was admitted with respiratory failure due to COVID-19 and developed a ST-elevation myocardial infarction (STEMI) during his admission. His coronary angiogram did not show any significant coronary artery disease other than a heavily thrombosed right coronary artery. In view of heavy thrombus burden, the right coronary artery was treated with thrombus retrieval using a distal embolic protection device in addition to manual thrombectomy and direct (intracoronary) thrombolysis without the need for implantation of a coronary stent. After successful revascularisation, triple antithrombotic therapy was instituted with an oral anticoagulant in addition to dual antiplatelets. This case illustrates the association of COVID-19 with coronary artery thrombosis, which may require disparate management of a STEMI than that resulting from atherosclerotic coronary artery disease.


2020 ◽  
Vol 27 (1) ◽  
pp. 13-26
Author(s):  
Ya. M. Lutay ◽  
O. M. Parkhomenko ◽  
Ye. B. Yershova ◽  
O. I. Irkin ◽  
S. M. Kozhukhov ◽  
...  

The aim – to determine the prevalence and major risk factors of intramyocardial hemorrhage (IMH) in timely revascularized patients with ST elevation myocardial infarction (STEMI), and to evaluate its importance for the development of postinfarction left ventricular (LV) dilatation. Materials and methods. We examined 24 patients with acute first anterior STEMI, who were admitted in the first six (on average 2.8±1.4) hours from symptoms development. The presence of IMH was assessed by cardiovascular magnetic resonance examination 3-4 days after primary percutaneous coronary intervention (pPCI). Echocardiography was performed during the first 24 hours and day 90 after acute myocardial infarction. LV dilatation was defined as at least 20 % increase of end-diastolic volume at 90 days. Endothelium-dependent flow-mediated brachial artery dilatation (FMD) was measured using high-resolution ultrasound at admission. Results and discussion. More than a third (37.5 %) of patients with anterior STEMI who underwent pPCI had signs of IMH. Hemorrhagic transformation of acute myocardial infarction was more often manifested in patients who were prescribed enoxaparin at the prehospital stage (RR = 3.75; 95 % CI 1.47–9.56) and less often in patients with multivessel (≥3) coronary artery disease (RR = 0.21; 95 % CI 0.03–1.00). There is a tendency to a more frequent detection of IMH in patients with endothelial dysfunction. Impaired reactive hyperemia (FMD ≤ 4.9 %) was associated with IMH development (RR 3.5; 95 % CI 0.9–13.5). The patients with IMH had a greater extent of myocardial damage according to CK-MB AUC and LGE at MRI and a more frequent development of postinfarction LV dilatation (RR 5.0; 95 % CI 1.3–19.7). The addition of intravenous quercetin started before pPCI to the standard basic treatment of acute myocardial infarction was associated with a significant decrease in the probability of hemorrhagic transformation (RR 0.21; 95 % CI 0.03–1.00). Conclusions. Pre-hospital administration of enoxaparin and endothelial dysfunction were the main predictors of IMH after pPCI in STEMI patients, whereas it was detected much less frequently in patients with multivessel (≥3) coronary artery disease. The presence of IMG has been associated with a greater extent of necrotized myocardium and more frequent development of postinfarction dilatation and dysfunction of the LV.


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