Pulmonary Function Tests in Emergency Department Pediatric Patients with Acute Wheezing/Asthma Exacerbation

Background. Pulmonary function tests (PFT) have been developed to analyze tidal breathing in patients who are minimally cooperative due to age and respiratory status. This study used tidal breathing tests in the ED to measure asthma severity.Design/Method. A prospective pilot study in pediatric patients (3 to 18 yrs) with asthma/wheezing was conducted in an ED setting using respiratory inductance plethysmography and pneumotachography. The main outcome measures were testing feasibility, compliance, and predictive value for admission versus discharge.Results. Forty patients were studied, of which, 14 (35%) were admitted. Fifty-five percent of the patients were classified as a mild-intermittent asthmatic, 30% were mild-persistent asthmatics, 12.5% were moderate-persistent asthmatics, and 2.5% were severe-persistent. Heart rate was higher in admitted patients as was labored breathing index, phase angle, and asthma score.Conclusions. Tidal breathing tests provide feasible, objective assessment of patient status in the enrolled age group and may assist in the evaluation of acute asthma exacerbation in the ED. Our results demonstrate that PFT measurements, in addition to asthma scores, may be useful in indicating the severity of wheezing/asthma and the need for admission.

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Relationship between pulmonary function tests, sputum eosinophilia and total serum IgE levels among asthmatic patients in Duhok, Iraq

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20202239 ◽

2020 ◽

Vol 8 (6) ◽

pp. 2033

Author(s):

Hamdia Yousif Issa ◽

Ali A. Ramadhan ◽

Abdulazeez S. Safo ◽

Omar A. M. Al Habib

Keyword(s):

Pulmonary Function ◽

Severe Asthma ◽

Inflammatory Markers ◽

Pulmonary Function Tests ◽

Asthma Severity ◽

Total Serum ◽

Serum Ige ◽

Sputum Eosinophilia ◽

Asthmatic Patients ◽

Function Tests

Background: Bronchial asthma is a disease characterized by reversible airway obstruction, airway inflammation; and hyper-responsiveness. The prevalence of asthma is high, and both its prevalence and burden have increased over the last several decades. The study of inflammatory markers has implications for the appropriate management of this disease. Inflammatory markers has implications for the appropriate management of this disease. Objective of the study is to determine the correlation between asthma severity using pulmonary function tests with sputum eosinophilia and total serum IgE levels.Methods: This case-control study was conducted from March 2017 to September 2018 in the respiratory unit of Azadi general teaching hospital. It included 42 asthmatic patients and 18 healthy subjects. They underwent pulmonary function tests and measurement of total serum IgE levels. Induced sputum was done for asthmatic patients.Results: The age of asthmatic patients ranged from 16-70 years (mean 42±19 years). The asthmatic patient’s female: male ratio was 1.8. Mild asthma was the most common severity group (N=18, 43%) followed by moderate asthma (N=14, 33%) then severe asthma (N=10, 24%). Abnormal sputum eosinophilia (≥3%) was detected in 90% of severe asthma (N=9) compared to 36% in moderate asthma (N=5) and 5.6% in mild asthma (N=1). There was significant statistical association between asthma severity and sputum eosinophilia (p=0.00004). The association between asthma severity and total serum IgE levels was highly significant (p<0.0000) with levels of total serum IgE increasing as the severity of asthma increases.Conclusions: Severe asthma is the least common severity group in this study. Both abnormal sputum eosinophilia and total serum IgE levels are associated with the severity of asthma.

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COMPARISON OF PEAK EXPIRATORY FLOW TO PULMONARY FUNCTION TESTS IN PEDIATRIC PATIENTS

CHEST Journal ◽

10.1378/chest.130.4_meetingabstracts.137s-c ◽

2006 ◽

Vol 130 (4) ◽

pp. 137S

Author(s):

Edith P. Allen ◽

Maria Martinez ◽

Roxann Wallace ◽

Lilia Parra-Roide ◽

Barbara Stewart

Keyword(s):

Pulmonary Function ◽

Peak Expiratory Flow ◽

Pediatric Patients ◽

Pulmonary Function Tests ◽

Function Tests ◽

Expiratory Flow

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Utility of Non-Effort Dependent Pulmonary Function Tests (NEDPFT) in Pediatric Emergency Department (ED) Patients with Acute Asthma Exacerbation

Pediatric Research ◽

10.1038/pr.2011.740 ◽

2011 ◽

Vol 70 ◽

pp. 515-515

Author(s):

K Giordano ◽

M E Rodriguez ◽

M Armani ◽

N Green ◽

J Richards ◽

...

Keyword(s):

Emergency Department ◽

Pulmonary Function ◽

Asthma Exacerbation ◽

Acute Asthma ◽

Pulmonary Function Tests ◽

Pediatric Emergency ◽

Pediatric Emergency Department ◽

Function Tests ◽

Acute Asthma Exacerbation

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Allergic rhinitis may impact the recovery of pulmonary function tests after moderate/severe asthma exacerbation in children

Allergy ◽

10.1111/all.12391 ◽

2014 ◽

Vol 69 (5) ◽

pp. 652-657 ◽

Cited By ~ 14

Author(s):

O. Yilmaz ◽

A. Bakirtas ◽

H. I. Ertoy Karagol ◽

E. Topal ◽

M. S. Demirsoy

Keyword(s):

Allergic Rhinitis ◽

Pulmonary Function ◽

Severe Asthma ◽

Asthma Exacerbation ◽

Pulmonary Function Tests ◽

Function Tests ◽

Severe Asthma Exacerbation

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Study of pulmonary function tests in tobacco factory workers

MedPulse International Journal of Physiology ◽

10.26611/103632 ◽

2018 ◽

Vol 6 (3) ◽

pp. 16-19

Author(s):

Gajanan V Patil ◽

◽

Atish Pagar ◽

U S Patil ◽

M K Parekh ◽

...

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Tests ◽

Factory Workers ◽

Function Tests

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A study on Variations of pulmonary function tests in different stages of pregnancy

Asian Pacific Journal of Health Sciences ◽

10.21276/apjhs.2016.3.3.7 ◽

2016 ◽

Vol 3 (3) ◽

pp. 45-48

Author(s):

N Bhaskar Rao ◽

◽

Ch Rambabu

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Tests ◽

Function Tests

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Pulmonary Function Tests in European Birth Cohorts

Current Respiratory Medicine Reviews ◽

10.2174/1573398x11309010002 ◽

2013 ◽

Vol 9 (1) ◽

pp. 3-10

Author(s):

Linus Grabenhenrich ◽

Cynthia Hohmann ◽

Remy Slama ◽

Joachim Heinrich ◽

Magnus Wickman ◽

...

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Tests ◽

Birth Cohorts ◽

Function Tests

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Pulmonary Function Tests Fail to Predict Exercise Intolerance in Sheep with Emphysema

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000158992.87523.c4 ◽

2005 ◽

Vol 37 (4) ◽

pp. 550-556

Author(s):

MELISSA R. MAZAN ◽

EDWARD P. INGENITO ◽

LARRY TSAI ◽

ANDREW HOFFMAN

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Tests ◽

Exercise Intolerance ◽

Function Tests

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ISOLATED ABNORMALITIES OF DIFFUSION CAPACITY (DLCO) IN PULMONARY FUNCTION TESTS AMONG INNER CITY PATIENTS

CHEST Journal ◽

10.1378/chest.134.4_meetingabstracts.s49004 ◽

2008 ◽

Vol 134 (4) ◽

pp. 49S

Author(s):

Ibrahim H. Abou Daya ◽

Muhammad U. Anwer ◽

Gilda Diaz-Fuentes ◽

Steve Blum ◽

Latha Menon

Keyword(s):

Pulmonary Function ◽

Inner City ◽

Pulmonary Function Tests ◽

Diffusion Capacity ◽

Function Tests

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Shrinking lung syndrome in pediatric systemic lupus erythematosus

Lupus ◽

10.1177/09612033211010331 ◽

2021 ◽

pp. 096120332110103

Author(s):

Alfonso Ragnar Torres Jimenez ◽

Nayma Ruiz Vela ◽

Adriana Ivonne Cespedes Cruz ◽

Alejandra Velazquez Cruz ◽

Alma Karina Bernardino Gonzalez

Keyword(s):

Systemic Lupus Erythematosus ◽

Pleural Effusion ◽

Pulmonary Function ◽

Lupus Erythematosus ◽

Pulmonary Function Tests ◽

Age At Diagnosis ◽

X Rays ◽

Systemic Lupus ◽

Function Tests ◽

Restrictive Pattern

Shrinking Lung Syndrome (SLS) is a rare and little known complication associated with Systemic Lupus Erythematosus (SLE), characterized by progressive and unexplainable dyspnea, pleuritic pain, small pulmonary volumes and elevation of the diaphragm on chest X-rays as well as restrictive pattern on pulmonary function tests. Objective To describe clinical, radiological and treatment characteristics in pediatric patients with SLS. Material and methods This is a descriptive and retrospective study in patients under 16 years old with the diagnosis of SLE complicated by SLS at the General Hospital. National Medical Center La Raza. Clinical, radiological and treatment variables were analyzed. Results are shown in frequencies and percentages. Results Data from 11 patients, 9 females and 2 males were collected. Mean age at diagnosis of SLS was 12.2 years. Age at diagnosis of SLE was 11.1 years. SLEDAI 17.3. Renal desease 72%, hematological 91%, lymphopenia 63%, mucocutaneous 72%, neurological 9%, arthritis 54%, serositis 91%, fever 81%, secondary antiphospholipid syndrome, low C3 72%, low C4 81%, positive ANA 91%, positive anti-DNA 91%. Regarding clinical manifestations of SLE: cough 81%, dyspnea 91%, hipoxemia 81%, pleuritic pain 71%, average oxygen saturation 83%. Chest X-rays findings: right hemidiaphragm affection 18%, left 63%, bilateral 18%. Elevated hemidiaphragm 91%, atelectasis 18%, pleural effusion 91%, over one third of the cardiac silhouette under the diphragm 36%, bulging diaphragm 45%, 5th. anterior rib that crosses over the diaphragm 91%. M-mode ultrasound: diaphragmatic hypomotility 100%, pleural effusion 63%. Pulmonary function tests: restrictive pattern in 45% of the cases. Treatment was with supplementary oxygen 100%, intubation 18%, antibiotics 100%, steroids 100%, intravenous immunoglobulin 54%, plasmapheresis 18%, cyclophosphamide 54% and rituximab 18%. The clinical course was favorable in 81%. Conclusions SLS should be suspected in patients with SLE and active disease who present hipoxemia, pleuritic pain, cough, dyspnea, pleural effusion and signs of restriction on chest X-rays. Therefore, a diaphragmatic M-mode ultrasound should be performed in order to establish the diagnosis.

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