scholarly journals Indications of Optical Coherence Tomography in Keratoplasties: Literature Review

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Thiago Trindade Nesi ◽  
Daniel Amorim Leite ◽  
Fábio Medina Rocha ◽  
Marco Antônio Tanure ◽  
Pedro Paulo Reis ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Literature Review ◽  
Early Identification ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Secondary Glaucoma ◽  
Optical Coherence

Optical coherence tomography (OCT) of the anterior segment, in particular corneal OCT, has become a reliable tool for the cornea specialist, as it provides the acquisition of digital images at high resolution with a noncontact technology. In penetrating or lamellar keratoplasties, OCT can be used to assess central corneal thickness and pachymetry maps, as well as precise measurements of deep stromal opacities, thereby guiding the surgeon to choose the best treatment option. OCT has also been used to evaluate the keratoplasty postoperative period, for early identification of possible complications, such as secondary glaucoma or donor disc detachments in endothelial keratoplasties. Intraoperatively, OCT can be used to assess stromal bed regularity and transparency in anterior lamellar surgeries, especially for those techniques in which a bare Descemet’s membrane is the goal. The purpose of this paper is to review and discuss the role of OCT as a diagnostic tool in various types of keratoplasties.

scholarly journals Correlation between Central Corneal Thickness and Degree of Myopia among Malaysian Patients Undergoing Laser Keratorefractive Surgery

2020 ◽  
pp. 52-58
Author(s):  
Sagili Chandrasekhara Reddy ◽  
Mohd Mansor Shariff ◽  
Aina Malindri Dasrilsyah
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Surgery ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Military Hospital ◽  
Moderate Degree ◽  
Optical Coherence ◽  
Corneal Refractive Surgery ◽  
The Mean

Purpose: To determine the central corneal thickness in myopic adult patients scheduled for laser corneal refractive surgery and to explore its correlation with degree of refractive error. Materials and Methods: The case records of 130 myopic patients who underwent laser corneal refractive surgery in a military hospital over a period of two years were reviewed to determine the central corneal thickness. All patients had 6/6 vision with best correction, and did not have any other anterior segment or fundus diseases in both eyes. The central corneal thickness was measured with Visante Carl Zeiss anterior segment optical coherence tomography instrument.                                                                                                                        Results: Out of 130 patients, males were more (73, 56.2%); mean age of patients was 33.8 years (range 18-60 years) and majority were Malays (110, 84.6%).  The spherical power of myopia ranged from – 0.5 to – 10.00 D, and the cylindrical power ranged from – 0.25 to – 3.25 D. The mean central corneal thickness of both eyes was 528.2 µm (range 331- 615 µm); in the mild degree of myopia (- 0.50 to - 2.00 D) 527.9 µm, moderate degree (- 2.25 to -5.00 D) 529.4 µm, and high degree (-5.25 to -11.00 D) 523.9 µm. Conclusion: The anterior segment optical coherence tomography provides noncontact, rapid, pachymetry mapping of the corneal thickness. In Malaysian patients, the mean central corneal thickness of both eyes in myopia was 528.1 µm (range 331- 615 µm). There was no correlation between the mean central corneal thickness and degree of myopia, different genders, age groups, ethnic groups and two eyes.

Central Corneal Thickness: Ultrasound Pachymetry Verus Anterior Segment Optical Coherence Tomography

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Waqas Ali ◽  
Munira Shakir ◽  
Sahira Wasim ◽  
Ronak Afza
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Mean Difference ◽  
P Value ◽  
Optical Coherence ◽  
Ultrasound Pachymetry ◽  
Group A ◽  
Group B

Purpose: To determine the mean difference in central corneal thickness between ultrasound pachymetry and anterior segment optical coherence tomography in patients visiting tertiary care hospital of Karachi Study design: Cross sectional study Place and Duration of Study: Department of Ophthalmology, Liaquat National Hospital, Karachi from 27th December 2018 to 26th June 2019. Methods: Total 216 eyes of 108 patients were divided into two groups. Central corneal thickness was measured using ultrasound pachymeters in group A and with anterior segment optical coherence tomography in group B. Data was collected and analyzed using SPSS version 21. Mean central corneal thickness was compared between the two methods. Stratification was done on gender, age and post-stratification independent sample t-test was applied for mean difference CCT and P-value ? 0.05 was taken as significant. Results: Total 108 patients were equally divided into two groups. Mean age was 48.70±7.82 years in group A and 50.66±6.88 years in group B. In group A, there were 74.1% males and 25.9% females while in group B, there were 75.9% males and 24.1% females. There was statistically significant difference between the mean central corneal thickness of group A and group B for right and left eyes (p<0.001). Mean difference was also compared for gender and age groups. We found statistically significant differences in central corneal thickness in between the two methods in both age groups (?45 years and > 45 years). Conclusion: Central corneal thickness was more with pachymeters as compared to the AS-OCT (p value < 0.05) Key Words: Central Corneal Thickness, Anterior Segment Optical Coherence Tomography, Ultrasound Pachymetry.

Effects of topical antiglaucomatous medications on central corneal epithelial thickness by anterior segment optical coherence tomography

2020 ◽  
Vol 30 (6) ◽  
pp. 1519-1524
Author(s):  
Emine Doğan ◽  
Burçin Köklü Çakır ◽  
Nilgün Özkan Aksoy ◽  
Erkan Celik ◽  
Ünal Erkorkmaz
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Tear Film ◽  
Optical Coherence ◽  
Corneal Epithelial ◽  
Duration Of Therapy ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness

Purpose: To evaluate the effect of topical antiglaucomatous medications on central corneal epithelial thickness measured by anterior segment optical coherence tomography. Materials and methods: A total of 153 eyes of 153 patients using topical antiglaucomatous medications and 110 eyes of 110 control subjects were enrolled. Glaucoma type, duration of therapy, the number of drugs, and drops/day were noted in the patient group. Patients and control subjects underwent ocular examinations including Schirmer test, slit lamp examination for tear film break-up time, and anterior segment optical coherence tomography for central corneal thickness and central corneal epithelial thickness. Central corneal epithelial thickness and other data were evaluated separately with regard to glaucoma type, duration of therapy, the number of drops, and drugs in the patient group. Results: The mean ages of the patients and controls were 60.1 ± 10.8 and 58.7 ± 11.2 years, respectively. The groups were similar with regard to mean age and gender (p = 0.058, p = 0.734, respectively). The median (interquartile range) central corneal thickness was 536 (54) µm in patients and 552 (53) µm in controls (p = 0.011). The median (interquartile range) central corneal epithelial thickness of patients and controls were 56 (4) µm and 60 (8) µm, respectively (p < 0.001). The median (interquartile range) tear film break-up time and Schirmer were 12 (6) s and 10 (8) mm in patients and 16 (2) s and 18 (4) mm in controls, respectively (p < 0.001, p < 0.001). In patient group, there was no significant difference in the median central corneal thickness, central corneal epithelial thickness, and tear film break-up time in terms of glaucoma type, duration of therapy, the number of drugs, and the number of daily drops. Only the median Schirmer test was found to be statistically lower in terms of number of daily eye drops (p = 0.039). Conclusion: Using topical antiglaucomatous medications seems to affect the central corneal epithelial thickness in glaucoma patients. Central corneal epithelial thickness was thinner in glaucoma patients than controls. Anterior segment optical coherence tomography might be helpful to evaluate the effect of antiglaucomatous medications on central corneal epithelial thickness during treatment.

scholarly journals Comparison of Four Methods for Corneal Thickness Measurement

2013 ◽  
Vol 6 (1) ◽  
pp. 37-42
Author(s):  
Teodora L. Marinova ◽  
Vesela Ivancheva ◽  
Svilena S. Peeva ◽  
Christina N. Grupcheva
Keyword(s):  
Optical Coherence Tomography ◽  
Laser Scanning ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Laser Scanning Confocal Microscopy ◽  
Thickness Measurement ◽  
Specular Microscopy ◽  
Optical Coherence ◽  
Cornea Thickness

Summary The aim of the study was to evaluate the thickness of the normal cornea in order to establish correlation between four methods of measuring including: ultrasound pachymetry (USP), anterior segment optical coherence tomography (ASOCT), non-contact tono/pachymetry (TONOPACHY) and laser-scanning confocal microscopy (LSCM). The study was based on evaluating repeatability and comparability of four different methods formeasuring the corneal thickness. Non contact specular microscopy was first performed on all 27 patients (aged between 20 and 24 years) to evaluate corneal characteristics and confirm the absence of pathological changes. Each participant was examined by USP, ASOCT and TONOPACHY, and 13 eyes of 10 persons were also examined by LSCM. The values of average central corneal thickness measured by USP, ASOCT, TONOPACHY and LSCM were 532.20±4.5 pm, 553.33±12.1 pm, were 548.20±5.62 pm and 573.33±7.22 pm, respectively. There was a high correlation between the instruments. The mean differences for central corneal thickness measurements were 41.43±1.67 pm between USP and LSCM, 20.43±2.4 pm between USP and ASOCT, and 22.1 ±3.88 pm between USB and TONOPACHY. Anterior segment optical coherence tomography overestimated corneal thickness as compared with that measured by USP, which is believed to be a gold standard. Anterior segment optical coherence tomography had better agreement with USP, as compared with LSCM. However, the results of measured cornea thickness by TONOPACHY were very close to cornea thickness measured by ASOCT.

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