A Case of Premature Ovarian Failure in a 33-Year-Old Woman

Objective. To assess aetiology of a POF in a 33-year-old woman and, if possible, plan a cure.Design. Case report.Setting. medical genetics diagnostic unit in a university hospital.Patient. A 33-year-old woman with premature ovarian failure (POF).Intervention(s). Genetic counseling, karyotyping, FISH study.Result(s). Turner-like diagnosis.Conclusion(s). Most cases of POF remain idiopathic. Turner syndrome can occur in very different phenotypes; cytogenetic and molecular profiling can provide a definitive diagnosis in cases with nonclassical phenotype.