HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level
Keyword(s):
B Virus
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Hepatocellular carcinoma (HCC) is a deadly and emerging disease leading to death in Asian countries. High hepatitis B virus (HBV) load and chronic hepatitis B (CHB) infection increase the risk of developing HCC. HBV is a DNA virus that can integrate DNA into host genome thereby increase the yield of transactivator protein HBxAg that may deregulate many pathways involving in metabolism of cells. Several monogenic and polygenic risk factors are also involved in HCC development. This review summarizes the mechanism involved in HCC development and discusses some promising therapies to make HCC curative.
2007 ◽
Vol 34
(5)
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pp. 373-378
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Epidemiology of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Related Hepatocellular Carcinoma
2018 ◽
Vol 12
(1)
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pp. 26-32
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Keyword(s):
2021 ◽
1987 ◽
Vol 84
(3)
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pp. 847-850
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Keyword(s):
2019 ◽
Vol 53
(1)
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pp. 51-57
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