scholarly journals Malignant Peripheral Nerve Sheath Tumour of the Maxilla

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Puja Sahai ◽  
Bidhu Kalyan Mohanti ◽  
Devajit Nath ◽  
Suman Bhasker ◽  
Subhash Chander ◽  
...  

A 38-year-old man was diagnosed with malignant peripheral nerve sheath tumour of the maxilla. He was treated with total maxillectomy. Histopathological examination of the resected specimen revealed a close resection margin. The tumour was of high grade with an MIB-1 labelling index of almost 60%. At six weeks following the surgery, he developed local tumour relapse. The patient succumbed to the disease at five months from the time of diagnosis. The present report underlines the locally aggressive nature of malignant peripheral nerve sheath tumour of the maxilla which necessitates an early therapeutic intervention. A complete resection with clear margins is the most important prognostic factor for malignant peripheral nerve sheath tumour in the head and neck region. Adjuvant radiotherapy may be considered to improve the local control. Future research may demarcate the role of targeted therapy for patients with malignant peripheral nerve sheath tumour.

2012 ◽  
Vol 13 (2) ◽  
pp. 219-221
Author(s):  
Amitava Sengupta ◽  
Ankan Bandyopadhyay ◽  
Debraj Jash ◽  
Kaushik Saha

Malignant peripheral nerve sheath tumours (MPNST) constitute a rare type of soft tissue sarcoma which arises from peripheral nerves or Schwann cells, perineural cells or fibroblasts. MPNST is a rare neoplasm affecting 1 in 1,00,000 population. Here we report a case of a 36 year old male who presented to us with an upper abdominal swelling for last 3 months. At first ,a diagnosis of type 1 neurofibromatosis type 1(NF-1) was made. Contrast enhanced CT scan abdomen and thorax revealed presence of a complex, heterogenous mass in upper abdomen with extension towards left hemithorax. Histopathological examination done from true cut biopsy specimen of the mass was suggestive of malignant peripheral nerve sheath tumour. Positivity of tumour cells on immunohistochemistry to S-100 established the diagnosis of MPNST in type 1 neurofibromatosis. In conclusion, it was a rare case of MPNST in a patient of NF-1. DOI: http://dx.doi.org/10.3329/jom.v13i2.12761 J Medicine 2012; 13 : 219-221


2018 ◽  
pp. bcr-2018-224481
Author(s):  
Ryoma Endo ◽  
Tomoko Tomioka ◽  
Ken Okada ◽  
Kanichi Inoue

2006 ◽  
Vol 42 (5) ◽  
pp. 210-212 ◽  
Author(s):  
Anacélia Mendes Fernandes ◽  
Aline Cristina Batista Rodrigues Johann ◽  
João Batista da Silveira-Júnior ◽  
Maria Cássia Ferreira de Aguiar ◽  
Maria Auxiliadora Vieira do Carmo ◽  
...  

2009 ◽  
Vol 19 (2) ◽  
pp. 217-220 ◽  
Author(s):  
Omid Dezfoulian ◽  
Sharam Jamshidi ◽  
Masoud Selk Ghaffari ◽  
Maria Tresa Capucchio ◽  
Majid Masoudifard ◽  
...  

2013 ◽  
Vol 113 (10) ◽  
pp. 628-631
Author(s):  
A. De-Stefano ◽  
G. Kulamarva ◽  
L. Citraro ◽  
L. Borgia ◽  
A. Croce

2006 ◽  
Vol 14 (1) ◽  
pp. 84-89 ◽  
Author(s):  
A Lesic ◽  
M Bumbasirevic ◽  
HDE Atkinson ◽  
R Maksimovic ◽  
J Sopta ◽  
...  

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