Analysis of the Time and Location of the Silicone Oil Emulsification by Spectral-Domain Optical Coherence Tomography after Silicone Oil Tamponade

Purpose. To estimate localization and the period up to the appearance of small hyperreflective round-shaped droplets using spectral-domain optical coherence tomography (SD-OCT) after pars plana vitrectomy with silicone oil tamponade.Methods. A retrospective observational study included 24 patients who had undergone pars plana vitrectomy with silicone oil tamponade for proliferative vitreoretinopathy (PVR) retinal detachment. SD-OCT analysis was performed 1, 3, and 6 months after surgery. We characterized the emulsified silicone oil in the SD-OCT as the small hyperreflective round-shaped droplets.Results. In SD-OCT examination, none of the patients had hyperreflective round-shaped droplets visible one month after vitrectomy with silicone oil tamponade. The hyperreflective droplets were found three months after surgery—in one patient above the optic nerve and in five patients intraretinally (in the cystoid spaces). Six months after vitrectomy, the hyperreflective round-shaped droplets were still present in the aforementioned patients' eyes and additionally in 3 eyes above the optic disc.Conclusions. Hyperreflective round-shaped droplets were found in a SD-OCT examination 3 months after silicone oil tamponade. The authors suggest that they are most likely the emulsified silicone oil droplets. The authors hypothesize that emulsification and migration of silicone oil begin within 3 months after surgery.

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Long-Term Changes of Macular Thickness after Pars Plana Vitrectomy in Optic Disc Pit Maculopathy: A Spectral-Domain Optical Coherence Tomography Study

Seminars in Ophthalmology ◽

10.3109/08820538.2015.1068345 ◽

2015 ◽

Vol 32 (3) ◽

pp. 302-308 ◽

Cited By ~ 8

Author(s):

Irini Chatziralli ◽

George Theodossiadis ◽

Dimitrios Panagiotidis ◽

Ioannis Emfietzoglou ◽

Vlassis Grigoropoulos ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Optic Disc ◽

Pars Plana Vitrectomy ◽

Spectral Domain ◽

Optical Coherence ◽

Optic Disc Pit ◽

Long Term Changes ◽

Pars Plana ◽

Optic Disc Pit Maculopathy

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A hierarchical framework for estimating neuroretinal rim area using 3D spectral domain optical coherence tomography (SD-OCT) optic nerve head (ONH) images of healthy and glaucoma eyes

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society ◽

10.1109/embc.2014.6944468 ◽

2014 ◽

Cited By ~ 6

Author(s):

Akram Belghith ◽

Christopher Bowd ◽

Robert N. Weinreb ◽

Linda M. Zangwill

Keyword(s):

Optical Coherence Tomography ◽

Optic Nerve ◽

Optic Nerve Head ◽

Spectral Domain ◽

Optical Coherence ◽

Hierarchical Framework ◽

Neuroretinal Rim ◽

Neuroretinal Rim Area ◽

Sd Oct

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Spectral domain optical coherence tomography (SD-OCT) assessment of the healthy female canine retina and optic nerve

Veterinary Ophthalmology ◽

10.1111/j.1463-5224.2011.00887.x ◽

2011 ◽

Vol 14 (6) ◽

pp. 400-405 ◽

Cited By ~ 30

Author(s):

Elena Hernandez-Merino ◽

Helga Kecova ◽

Samantha J. Jacobson ◽

Karl N. Hamouche ◽

Richard N. Nzokwe ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Optic Nerve ◽

Spectral Domain ◽

Optical Coherence ◽

Healthy Female ◽

Sd Oct

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Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

BMC Ophthalmology ◽

10.1186/1471-2415-14-76 ◽

2014 ◽

Vol 14 (1) ◽

Cited By ~ 8

Author(s):

Otto Alexander Maneschg ◽

Éva Volek ◽

János Németh ◽

Gábor Márk Somfai ◽

Zsuzsanna Géhl ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Cataract Surgery ◽

Pars Plana Vitrectomy ◽

Spectral Domain ◽

Postoperative Endophthalmitis ◽

Optical Coherence ◽

Successful Management ◽

Pars Plana

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In VivoComparison of 23- and 25-Gauge Sutureless Vitrectomy Incision Architecture Using Spectral Domain Optical Coherence Tomography

Journal of Ophthalmology ◽

10.1155/2013/347801 ◽

2013 ◽

Vol 2013 ◽

pp. 1-5 ◽

Cited By ~ 4

Author(s):

Anderson Teixeira ◽

Flavio A. Rezende ◽

Camila Salaroli ◽

Nonato Souza ◽

Benedito Antonio Sousa ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Silicone Oil ◽

Spectral Domain ◽

Optical Coherence ◽

Open Wound ◽

Longitudinal Length ◽

Oil Residue ◽

23 Gauge ◽

Sd Oct

Purpose. To investigate thein vivoincision architecture using spectral domain optical coherence tomography (SD-OCT) in 23-gauge and 25-gauge transconjunctival suturelesspars planavitrectomy (TSPPV).Methods. A prospective observational study of 22 eyes of 22 patients that underwent three-port 25-gauge (10 eyes) or 23-gauge (12 eyes) TSPPV was performed. The three sclerotomies sites in each eye were analyzed by Corneal Adapter Model (CAM) RTVue SD-OCT (Optovue Inc., Fremont, CA, USA) with wound cross-section images (longitudinal and transversal) on days 1, 7, and 30 postoperatively. Transversal and longitudinal length, location, angle between the conjunctival surface tangent and the incision plane, and architecture deformations were evaluated.Results. All patients (22 eyes) completed the study and surgeries lasted less than 60 minutes. All wounds were obliquely performed, 23-gauge mean angle was 23 ± 5°, and 25-gauge angule was 21 ± 4°. Twenty-three-gauge sclerotomy transversal mean length was 1122 ± 242 μm and 25-gauge transversal sclerotomy mean length was 977 ± 174 μm; 23-gauge longitudinal mean length was 363 ± 42 μm and 25-gauge longitudinal sclerotomy mean length was 234 ±19 μm; 23-gauge open wound thickness mean was 61 ± 28 μm and 25-gauge open wound thickness mean was 22 ± 6 μm. All results were statistically significant (P<0.05). No vitreous incarceration or silicone oil residue was observed in incision sites with both gauges.Conclusions. The 23-gauge and 25-gauge architectural wound constructions were well visualized using CAM SD-OCT. Statistical differences between the two gauges were observed throughout the study period.

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USING SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING TO IDENTIFY THE PRESENCE OF RETINAL SILICONE OIL EMULSIFICATION AFTER SILICONE OIL TAMPONADE

Retina ◽

10.1097/iae.0b013e318287d9ea ◽

2013 ◽

Vol 33 (8) ◽

pp. 1567-1573 ◽

Cited By ~ 20

Author(s):

Marie-Hélène Errera ◽

Sidath E. Liyanage ◽

Mostafa Elgohary ◽

Alexander C. Day ◽

Louisa Wickham ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Silicone Oil ◽

Spectral Domain ◽

Optical Coherence ◽

Tomography Imaging ◽

Optical Coherence Tomography Imaging ◽

Silicone Oil Tamponade

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Pediatric spectral domain optical coherence tomography (SD-OCT) normative data for novel optic nerve parameters using the Heidelberg Spectralis

Journal of American Association for Pediatric Ophthalmology and Strabismus ◽

10.1016/j.jaapos.2015.07.064 ◽

2015 ◽

Vol 19 (4) ◽

pp. e25

Author(s):

Gena Heidary ◽

Frank Weng ◽

Linda R. Dagi

Keyword(s):

Optical Coherence Tomography ◽

Optic Nerve ◽

Normative Data ◽

Spectral Domain ◽

Optical Coherence ◽

Sd Oct

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The Influence of Silicone Oil on the Ganglion Cell Complex After Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Current Pharmaceutical Design ◽

10.2174/1381612824666180813115438 ◽

2018 ◽

Vol 24 (29) ◽

pp. 3476-3493 ◽

Cited By ~ 5

Author(s):

Dorota Raczyńska ◽

Kamila Mitrosz ◽

Krystyna Raczyńska ◽

Leopold Glasner

Keyword(s):

Retinal Detachment ◽

Ganglion Cell ◽

Pars Plana Vitrectomy ◽

Silicone Oil ◽

Cell Complex ◽

Ganglion Cell Complex ◽

Pars Plana ◽

Silicone Oil Tamponade ◽

The Impact ◽

Sd Oct

Purpose: Pars plana vitrectomy (PPV) and silicone oil endotamponade have been used as a treatment in rhegmatogenous retinal detachment (RRD). Improvement in the modality of spectral-domain optical coherence tomography (SD-OCT) allows for the assessment of ganglion cell layer-inner plexiform layer (GCL-IPL) in the macular region. Information about the GCL-IPL status may be a response to the question as to why the visual recovery after PPV with silicone oil tamponade is incomplete. The aim of the study was to evaluate the impact of silicone oil on GCL-IPL and compare it with other endotamponade types such as Sulfur hexafluoride gas (SF6), Perfluoropropane gas (C3F8) used during PPV performed due to RRD. Patients and Methods: The study involved 57 eyes after PPV and 57 healthy, control eyes of patients with primary RRD who had undergone successful PPV. The patients were divided into three subgroups depending on the endotamponade type, and were tracked with complete ophthalmological examination during a period of 6 months. PPV with internal tamponade silicone oil, 24% SF6 or 14% C3F8 was performed. The medical records were reviewed and compared between the groups. Results: SD-OCT analysis detected a significant reduction of average GCL-IPL thickness and reduction of GCLIPL parameter in almost all examined sectors in the group with silicone oil endotamponade during all follow-up visits (P<0.05). The study showed a significant vision deterioration in the silicone oil group in comparison with the SF6 group on all follow-up visits (P<0.05). Conclusion: This is the first in vivo SD-OCT study describing the toxic effect of silicone oil endotamponade on GCL-IPL complex after PPV for RRD. The study confirmed that the GCL-IPL complex value can be a predictive factor for assessing the final visual acuity. SD-OCT should be recommended as a clinical standard in the followup treatment of patients after PPV for RRD, especially with the use of silicone oil endotamponade. Plain Language Summary: The aim of the study was to examine the impact of silicone oil on the ganglion cell complex. The ganglion cell is a neuron type located in the retina and takes part in transmitting visual information from the retina to the brain. Silicone oil is a substance used during eye surgery called pars plana vitrectomy. This tamponade type acts to hold the retina in a proper position. However, during the retinal detachment, which is the separation of the retina from the layer underneath, a reduction of neurons is observed. We decided to use a new technology device called SD-OCT to determine the thickness of the ganglion cell complex. We compared the impact of silicone oil with other tamponade types. We found that silicone oil causes a reduction in the ganglion cell complex. Moreover, we observed vision deterioration in eyes treated with a silicone oil tamponade. The research describes the toxic effect of silicone oil on ganglion cells. Ganglion cell values may be used to determine visual improvement or deterioration after eye surgery with silicone oil tamponade. SD-OCT should be a clinical standard in monitoring patients with silicone oil tamponade.

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