The Influence of Silicone Oil on the Ganglion Cell Complex After Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

2018 ◽  
Vol 24 (29) ◽  
pp. 3476-3493 ◽  
Author(s):  
Dorota Raczyńska ◽  
Kamila Mitrosz ◽  
Krystyna Raczyńska ◽  
Leopold Glasner
Keyword(s):  
Retinal Detachment ◽  
Ganglion Cell ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Cell Complex ◽  
Ganglion Cell Complex ◽  
Pars Plana ◽  
Silicone Oil Tamponade ◽  
The Impact ◽  
Sd Oct

Purpose: Pars plana vitrectomy (PPV) and silicone oil endotamponade have been used as a treatment in rhegmatogenous retinal detachment (RRD). Improvement in the modality of spectral-domain optical coherence tomography (SD-OCT) allows for the assessment of ganglion cell layer-inner plexiform layer (GCL-IPL) in the macular region. Information about the GCL-IPL status may be a response to the question as to why the visual recovery after PPV with silicone oil tamponade is incomplete. The aim of the study was to evaluate the impact of silicone oil on GCL-IPL and compare it with other endotamponade types such as Sulfur hexafluoride gas (SF6), Perfluoropropane gas (C3F8) used during PPV performed due to RRD. Patients and Methods: The study involved 57 eyes after PPV and 57 healthy, control eyes of patients with primary RRD who had undergone successful PPV. The patients were divided into three subgroups depending on the endotamponade type, and were tracked with complete ophthalmological examination during a period of 6 months. PPV with internal tamponade silicone oil, 24% SF6 or 14% C3F8 was performed. The medical records were reviewed and compared between the groups. Results: SD-OCT analysis detected a significant reduction of average GCL-IPL thickness and reduction of GCLIPL parameter in almost all examined sectors in the group with silicone oil endotamponade during all follow-up visits (P<0.05). The study showed a significant vision deterioration in the silicone oil group in comparison with the SF6 group on all follow-up visits (P<0.05). Conclusion: This is the first in vivo SD-OCT study describing the toxic effect of silicone oil endotamponade on GCL-IPL complex after PPV for RRD. The study confirmed that the GCL-IPL complex value can be a predictive factor for assessing the final visual acuity. SD-OCT should be recommended as a clinical standard in the followup treatment of patients after PPV for RRD, especially with the use of silicone oil endotamponade. Plain Language Summary: The aim of the study was to examine the impact of silicone oil on the ganglion cell complex. The ganglion cell is a neuron type located in the retina and takes part in transmitting visual information from the retina to the brain. Silicone oil is a substance used during eye surgery called pars plana vitrectomy. This tamponade type acts to hold the retina in a proper position. However, during the retinal detachment, which is the separation of the retina from the layer underneath, a reduction of neurons is observed. We decided to use a new technology device called SD-OCT to determine the thickness of the ganglion cell complex. We compared the impact of silicone oil with other tamponade types. We found that silicone oil causes a reduction in the ganglion cell complex. Moreover, we observed vision deterioration in eyes treated with a silicone oil tamponade. The research describes the toxic effect of silicone oil on ganglion cells. Ganglion cell values may be used to determine visual improvement or deterioration after eye surgery with silicone oil tamponade. SD-OCT should be a clinical standard in monitoring patients with silicone oil tamponade.

scholarly journals Tonic Pupil Following Pars Plana Vitrectomy and Endolaser

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Benyamin Ebrahim ◽  
Larry Frohman ◽  
Marco Zarbin ◽  
Neelakshi Bhagat
Keyword(s):  
Retinal Detachment ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Retrobulbar Anesthesia ◽  
Tonic Pupil ◽  
Suprachoroidal Space ◽  
Pars Plana ◽  
Silicone Oil Tamponade

Tonic pupil was observed in a 67 year-old patient following a retinal detachment repair with pars plana vitrectomy, endolaser and silicone oil tamponade performed under retrobulbar anesthesia. The probable location of disturbance is the postganglionic parasympathetic fibers in the short ciliary nerves along their course to the pupil in the suprachoroidal space. A likely explanation for this phenomenon is injury to short ciliary nerves by endolaser treatment.

scholarly journals Corneal endothelial changes induced by pars plana vitrectomy with silicone oil tamponade for retinal detachment

2021 ◽  
Vol 22 (3) ◽  
Author(s):  
Corina Coman (Cernat) ◽  
Daniel Malita ◽  
Simona Stanca ◽  
Stella Patoni (Popescu) ◽  
Ovidiu Musat ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Pars Plana ◽  
Silicone Oil Tamponade

scholarly journals Analysis of the Time and Location of the Silicone Oil Emulsification by Spectral-Domain Optical Coherence Tomography after Silicone Oil Tamponade

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Dominik Odrobina ◽  
Iwona Laudańska-Olszewska
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Pars Plana ◽  
Silicone Oil Tamponade ◽  
And Migration ◽  
Sd Oct

Purpose. To estimate localization and the period up to the appearance of small hyperreflective round-shaped droplets using spectral-domain optical coherence tomography (SD-OCT) after pars plana vitrectomy with silicone oil tamponade.Methods. A retrospective observational study included 24 patients who had undergone pars plana vitrectomy with silicone oil tamponade for proliferative vitreoretinopathy (PVR) retinal detachment. SD-OCT analysis was performed 1, 3, and 6 months after surgery. We characterized the emulsified silicone oil in the SD-OCT as the small hyperreflective round-shaped droplets.Results. In SD-OCT examination, none of the patients had hyperreflective round-shaped droplets visible one month after vitrectomy with silicone oil tamponade. The hyperreflective droplets were found three months after surgery—in one patient above the optic nerve and in five patients intraretinally (in the cystoid spaces). Six months after vitrectomy, the hyperreflective round-shaped droplets were still present in the aforementioned patients' eyes and additionally in 3 eyes above the optic disc.Conclusions. Hyperreflective round-shaped droplets were found in a SD-OCT examination 3 months after silicone oil tamponade. The authors suggest that they are most likely the emulsified silicone oil droplets. The authors hypothesize that emulsification and migration of silicone oil begin within 3 months after surgery.

scholarly journals Posterior pole retinotomy for treatment of recurrent macular hole retinal detachment in highly myopic eyes: a pilot study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xianggui Wang ◽  
Xuezhi Zhou ◽  
Ying Zhu ◽  
Huizhuo Xu
Keyword(s):  
Retinal Detachment ◽  
Macular Hole ◽  
Pars Plana Vitrectomy ◽  
Silicone Oil ◽  
Posterior Pole ◽  
Macular Holes ◽  
Macular Hole Retinal Detachment ◽  
Pars Plana ◽  
Silicone Oil Tamponade ◽  
Hole Closure

Abstract Background To investigate the feasibility and efficacy of posterior pole retinotomy to treat recurrent macular hole retinal detachment (MHRD) in highly myopic patients. Methods We performed a retrospective study and reviewed the medical records in our hospital between January 1, 2016 and December 31, 2018. Highly myopic patients who received posterior pole retinotomy with silicone oil tamponade for their recurrent MHRD after pars plana vitrectomy were included in the analysis. Postoperative retinal reattachment, best-corrected visual acuity (BCVA), macular hole closure, and complications were evaluated. Results There were 11 patients (11 eyes) included in this study. All retinas were reattached. Silicone oil was successfully removed from all eyes 1.5–3 months after the surgery. Macular holes were completely closed in three eyes and remained flat open in eight eyes. The BCVA of all eyes improved significantly at 12 months after surgery (logarithm of the minimal angle of resolution, pre vs. postoperatively, 1.87 ± 0.44 vs. 1.15 ± 0.24, P < 0.05). None of the patients had complications such as endophthalmitis, fundus hemorrhage, retinal redetachment, and proliferative vitreoretinopathy. Conclusion Posterior pole retinotomy is a safe and effective surgery to treat recurrent MHRD after pars plana vitrectomy in highly myopic patients.

scholarly journals Macular Ganglion Cell Layer Thickness after Macula-Off Rhegmatogenous Retinal Detachment Repair: Scleral Buckling versus Pars Plana Vitrectomy

2020 ◽  
Vol 9 (5) ◽  
pp. 1411
Author(s):  
Magda Gharbiya ◽  
Giuseppe Maria Albanese ◽  
Andrea Maria Plateroti ◽  
Michela Marcelli ◽  
Marco Marenco ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Ganglion Cell ◽  
Pars Plana Vitrectomy ◽  
Rhegmatogenous Retinal Detachment ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Scleral Buckling ◽  
Pars Plana ◽  
Fellow Eyes ◽  
Sd Oct

(1) Background: We evaluated macular ganglion cell layer–inner plexiform layer (GCL-IPL) thickness in patients with primary macula-off rhegmatogenous retinal detachment (RRD) treated with scleral buckling (SB) or pars plana vitrectomy (PPV) using spectral domain optical coherence tomography (SD-OCT). (2) Methods: In this retrospective, observational study, we reviewed the medical records of patients undergoing SB or PPV surgery for macula-off RRD. SD-OCT was performed at three and 12 months after surgery. The central and parafoveal GCL-IPL thicknesses in treated eyes were compared with those of healthy fellow eyes. OCT measurements between the SB and PPV group were also compared using the analysis of covariance. (3) Results: Seventy-one eyes of 71 patients with a mean age of 61.2 ± 11.7 years were included. The parafoveal GCL-IPL thickness of the PPV group was significantly reduced, with respect to fellow eyes, at three and 12 months (p < 0.01). After adjusting for age, axial length, spherical equivalent, RD extent, preoperative intraretinal cysts, duration of symptoms and postoperative IOP, the parafoveal GCL-IPL thickness in the PPV group was significantly reduced with respect to the SB group, both at three and 12 months (F = 11.45, p = 0.001 and F = 12.37, p = 0.001, respectively). (4) Conclusions: In conclusion, the GCL-IPL is reduced in thickness in eyes with macula-off RRD treated with vitrectomy and is significantly thinner compared to eyes undergoing scleral buckling surgery.

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