scholarly journals Kytococcus schroeteriBacteremia in a Patient with Hairy Cell Leukemia: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Akshay Amaraneni ◽  
Devin Malik ◽  
Sakshi Jasra ◽  
Sreenivasa R. Chandana ◽  
Deepak Garg

TheKytococcusgenus formerly belonged toMicrococcus. The first report of aKytococcus schroeteriinfection was in 2002 in a patient diagnosed with endocarditis. We report a case of central line associatedKytococcus schroeteribacteremia in a patient with underlying Hairy Cell Leukemia.Kytococcus schroeteriis an emerging infection in the neutropenic population and in patients with implanted artificial tissue. It is thought to be a commensal bacterium of the skin; however, attempts to culture the bacteria remain unsuccessful. There have been a total of 5 cases (including ours) ofK. schroeteribacteremia in patients with hematologic malignancies and neutropenia and only 18 documented cases in any population. Four of the cases of bacteria in neutropenic patients have been fatal, but early detection and treatment could make a difference in clinical outcomes.

Leukemia ◽  
2003 ◽  
Vol 17 (10) ◽  
pp. 2057-2059 ◽  
Author(s):  
G Schiller ◽  
J Said ◽  
S Pal

2016 ◽  
Vol 102 (2_suppl) ◽  
pp. S124-S127 ◽  
Author(s):  
Alessandro Broccoli ◽  
Letizia Gandolfi ◽  
Cinzia Pellegrini ◽  
Claudio Agostinelli ◽  
Lisa Argnani ◽  
...  

Blood ◽  
1994 ◽  
Vol 83 (9) ◽  
pp. 2637-2645 ◽  
Author(s):  
U Haglund ◽  
G Juliusson ◽  
B Stellan ◽  
G Gahrton

Abstract Cytogenetic analysis was performed on B-cell mitogen-stimulated cells from 36 patients with symptomatic hairy cell leukemia. Evaluable metaphases were achieved from 30 patients, and (67%) showed clonal abnormalities. Recurrent chromosomal aberrations involving chromosomes 1, 2, 5, 6, 11, 19, and 20 were found. The abnormalities were mostly deletions and inversions, whereas translocations and numerical abnormalities, except trisomy 5, were rare. Fourteen patients showed multiple clones, which mostly were unrelated and found in different combinations in individual cells. Cells with non-clonal abnormalities identical to those found in clonal changes in other patients were common. Chromosome 5 was involved in clonal aberrations in 12 of 30 (40%) patients, most commonly as trisomy 5 (n = 4), or pericentric inversions (n = 6) and interstitial deletions (n = 4) involving band 5q13. Three patients showed two and 1 patient three different clones that involved chromosome 5. In addition, 1 patient had a rare constitutional inversion of chromosome 5 with breakpoints at p13.1 and q13.3. Pericentric inversions and interstitial deletions of chromosome 2 occurred clonally in 4 patients (13%) and in single cells of another 6 patients. Deletions of chromosome 1 at band q42 was found in 5 patients, and 1 patient had a translocation between 1q42 and a supernumerary chromosome 5. Deletions of 6q and 11q were similar to those commonly found in other lymphoproliferative disorders. Trisomy 5, structural abnormalities involving the pericentromeric regions of chromosomes 5 and 2, and 1q42 abnormalities were findings distinguishing the karyotypes in hairy cell leukemia from those of other hematologic malignancies.


1992 ◽  
Vol 65 (3) ◽  
pp. 138-142 ◽  
Author(s):  
E. Weeks ◽  
C. M. Jones ◽  
V. Guinee ◽  
R. Shallenberger ◽  
G. A. Sarosi ◽  
...  

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