scholarly journals Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Nina Ni ◽  
Marc A. Goldberg ◽  
Ralph C. Eagle ◽  
Christopher J. Rapuano ◽  
Julia A. Haller

Purpose. To present the clinical and histopathologic correlation of two cases of epithelial downgrowth (EDG) after prior intraocular surgery.Methods. Observational case reports.Results. We present two cases of EDG occurring after intraocular surgery. In both cases, after two anterior chamber injections of 5-fluorouracil (5FU), the area of EDG initially regressed. In Case 1, a limited area of EDG eventually recurred, and penetrating keratoplasty with cryotherapy was curative. In Case 2, subsequent corneal edema required Descemet-stripping automated endothelial keratoplasty, and the patient remained clinically free of EDG without further treatment.Conclusion. Intracameral 5FU may have a role in the treatment of EDG after intraocular surgery, though its precise utilization and impact remain to be defined.

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Sabah S. Jastaneiah

This Interventional case reports a challenging case of descemet’s stripping-automated endothelial keratoplasty (DSAEK) in a young male patient with traumatic aniridia, aphakia, and corneal edema. Surgery was planned in two stages; first was implantation of aniridia intraocular lens (AIOL), few months later, DSAEK procedure was performed. Successful outcome of both procedures was achieved as measured by the stability of the AIOL, clarity of the cornea, attachment of the lenticule, and improvement in vision. Aniridia implant supports a sufficient amount of air in the anterior chamber especially if the posterior segment is well formed, while providing the required lens power to improve vision. DSAEK procedure challenges that include iris defects and aphakia may be overcome by stepwise planning of the procedure.


Author(s):  
Hanna Garzozi ◽  
Yossef Pickel ◽  
Ankur Barua

ABSTRACT Corneal cross-linking has proven safety and efficacy in arresting the progression of keratoconus. Its use has been extended to resolution of corneal edema. We present a case report and review of literature on the treatment of corneal edema using corneal cross-linking. Corneal cross-linking seems to be an effective method in reducing corneal edema at least as a temporary measure till definitive solution, such as penetrating keratoplasty (PKP) or Descemet's stripping automated endothelial keratoplasty (DASEK) is preformed. How to cite this article Barbara R, Garzozi H, Barbara A, Pickel Y, Barua A. Collagen Corneal Cross-linking in a Keratoconic Eye with Diffuse Corneal Edema. Int J Kerat Ect Cor Dis 2012;1(2):134-139.


2012 ◽  
Vol 32 (1) ◽  
pp. 9-14 ◽  
Author(s):  
George R. Wandling ◽  
Matthew P. Rauen ◽  
Kenneth M. Goins ◽  
Anna S. Kitzmann ◽  
John E. Sutphin ◽  
...  

2021 ◽  
Vol 13 ◽  
pp. 251584142110277
Author(s):  
Zahra Ashena ◽  
Thomas Hickman-Casey ◽  
Mayank A. Nanavaty

A 65-year-old patient with history of keratoconus, mild cataract and penetrating keratoplasty over 30 years ago developed corneal oedema subsequent of graft failure with best corrected visual acuity (BCVA) of counting fingers. He underwent a successful cataract surgery combined with a 7.25 mm Descemet’s Membrane Endothelial Keratoplasty (DMEK) with Sodium Hexafluoride (SF6) gas. His cornea remained oedematous inferiorly at 4 weeks, despite two subsequent re-bubbling due to persistent DMEK detachment inferiorly. This was managed by three radial full thickness 10-0 nylon sutures placed in the inferior cornea along with intracameral injection of air. Following this, his anterior segment ocular coherence tomography (OCT) confirmed complete attachment of the graft, and the sutures were removed 4 weeks later. Unaided visual acuity was 20/63 and BCVA was 20/32 after 8 months. DMEK suturing can be helpful in persistent DMEK detachments, which is refractory to repeated re-bubbling due to uneven posterior surface of previous PK.


2016 ◽  
Vol 172 ◽  
pp. 58-63 ◽  
Author(s):  
Sarah B. Weissbart ◽  
Kristin M. Hammersmith ◽  
Brandon D. Ayres ◽  
Christopher J. Rapuano ◽  
Parveen K. Nagra ◽  
...  

2021 ◽  
pp. 112067212110378
Author(s):  
Gonzalo García de Oteyza ◽  
Guido Bregliano ◽  
Irene Sassot ◽  
Luis Quintana ◽  
Carolina Rius ◽  
...  

Acute corneal hydrops usually resolves alone or with medical therapy along the first 4–6 weeks. However, depending on the severity of the corneal edema or the size of the Descemet break, self-healing might be difficult. Years ago, those patients had no more options than corneal transplantation, but surgical alternatives are on the rise in this century. These surgeries are becoming more popular with a variety of techniques relegating penetrating keratoplasty to a residual role. These techniques aim to accelerate corneal healing, reduce the edema, improve visual acuity and prevent from severe complications that may appear if corneal hydrops is not treated rapidly. Feasibility and safety are the favorable aspects of these techniques since the complications rates described remain low. In this review, we emphasize the recently published studies that describe both the techniques and their results.


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