scholarly journals Gastric Residual Volume after Split-Dose Bowel Preparation versus Conventional Single-Dose Regimen before Anesthetic Colonoscopy

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Shi-gui Xue ◽  
Han-lin Chen ◽  
Chun-sheng Cheng ◽  
Bao-sheng Huang ◽  
Hou-de Zhang
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Dose Group ◽  
Prospective Observational Study ◽  
Residual Volume ◽  
Gastric Residual Volume ◽  
Split Dose ◽  
Bowel Cleansing ◽  
Risk Of Aspiration

The aim of this study was to compare gastric residual volume (GRV) in patients given a split-dose versus a conventional single-dose of polyethylene glycol (PEG) preparation before undergoing anesthetic colonoscopy. Methods. In a prospective observational study, we assessed GRV in outpatients undergoing same-day anesthetic gastroscopy and colonoscopy between October 8 and December 30 of 2016. Outpatients were assigned to the split-dose (1 L PEG in the prior evening and 1 L PEG 2–4 h before endoscopy) or single-dose (ingestion of 2 L PEG ≥ 6 h before endoscopy) regimen randomly. Bowel cleansing quality was assessed with the Boston Bowel Preparation Scale (BBPS). Results. The median GRV in the split-dose group (17 ml, with a range of 0–50 ml; N=65) was significantly lower than that in the single-dose group (22 ml, with a range of 0–62 ml; N=64; p=0.005), with a better bowel cleansing quality (BBPS score 8.05±0.82 versus 7.64±1.21; p=0.028). GRV was not associated with diabetes or the use of medications. Conclusions. GRV after a split-dose preparation and fasting for 2–4 hours is not larger than that after a conventional single-dose preparation and fasting for 6–8 hours. The data indicates that the split-dose bowel preparation might not increase the risk of aspiration.

Comparison of Gastric Residual Volume and pH between Single and Split-Dose Bowel Preparation in Patients Undergoing Esophago-Gastro-Duodenoscopy and Colonoscopy: A Randomized Controlled Trial

2021 ◽  
Vol 104 (10) ◽  
pp. 1597-1603
Keyword(s):  
Single Dose ◽  
Bowel Preparation ◽  
Controlled Trial ◽  
Latency Period ◽  
Residual Volume ◽  
Gastric Residual Volume ◽  
Anesthetic Care ◽  
Split Dose ◽  
Colon Cleansing ◽  
Bowel Cleansing

Background: Colonoscopy is an effective surveillance for the diagnosis and screening of colorectal cancer (CRC). Prior to the procedure, people would take laxatives for a good visualization of bowel texture. Although a split-dose bowel preparation has become popular, many anesthesiologists are concerned about pulmonary aspiration. Objective: To study the gastric residual volume and pH in patients taking split-dose bowel preparation as compared to those having laxatives on the day before the procedure. Materials and Methods: One hundred patients were randomized equally into two groups, as A for a single-dose, and B for a split-dose regimen. All patients underwent endoscopy under standard anesthetic care. The total gastric residual volume was suctioned, and pH was measured through the endoscope. The surgical team was unaware of the study protocol. The quality of bowel cleansing was assessed by the endoscopist using the Boston Bowel Preparation Scale (BBPS). Results: The bowel cleansing, the latency period, the endoscopist and patients’ satisfaction of single-and split-dose group were 7.06±1.4 and 8.14±1.1, 13.3±1.1 and 4.2±0.4 hours, 62.0% and 94.0%, and 90.0% and 74.0%, respectively. They all showed statistically significant differences between the two groups (p<0.05). Conclusion: The gastric residual volume and pH were not different between the split and single-dose preparations. Therefore, it might not increase the risk of aspiration pneumonitis. However, the split-dose technique was more effective in colon cleansing, patients’ tolerability, acceptability, and compliance than the preparations administered entirely the day or evening before the surgical procedure. Keywords: Gastro-colonoscopy; Single-dose bowel preparation; Split-dose bowel preparation; Gastric residual volume; Anesthesia

Gastric residual volume after split-dose compared with evening-before polyethylene glycol bowel preparation

2016 ◽  
Vol 83 (3) ◽  
pp. 574-580 ◽  
Author(s):  
Deepak Agrawal ◽  
Benjamin Elsbernd ◽  
Amit G. Singal ◽  
Don Rockey
Keyword(s):  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Residual Volume ◽  
Gastric Residual Volume ◽  
Split Dose

Sa1061 Split-Dose Bowel Preparation Does Not Increase Gastric Residual Volume as Compared With Day Prior Preparations: A Systematic Review and Network Meta-Analysis

2017 ◽  
Vol 85 (5) ◽  
pp. AB174-AB175 ◽  
Author(s):  
Danny J. Avalos ◽  
Majd Michael ◽  
Fernando Castro-Pavia ◽  
Daniel Sussman ◽  
Jose L. Gonzalez Martinez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Residual Volume ◽  
Gastric Residual Volume ◽  
Split Dose

scholarly journals Split-Dose Polyethylene Glycol Is Superior to Single Dose for Colonoscopy Preparation: Results of a Randomized Controlled Trial

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Rachid Mohamed ◽  
Robert J. Hilsden ◽  
Catherine Dube ◽  
Alaa Rostom
Keyword(s):  
Single Dose ◽  
Bowel Preparation ◽  
Dose Group ◽  
Controlled Trial ◽  
Polyp Detection ◽  
Split Dose ◽  
Screening Clinic ◽  
The Right ◽  
Colonoscopy Preparation ◽  
To Receive

Background. The efficacy of colonoscopy in detecting abnormalities within the colon is highly dependent on the adequacy of the bowel preparation. The objective of this study was to compare the efficacy, safety, and tolerability of PEG lavage and split-dose PEG lavage with specific emphasis on the cleanliness of the right colon.Methods. The study was a prospective, randomized, two-arm, controlled trial of 237 patients. Patients between the age of 50 and 75 years were referred to an outpatient university screening clinic for colonoscopy. Patients were allocated to receive either a single 4 L PEG lavage or a split-dose PEG lavage.Results. Overall, the bowel preparation was superior in the split-dose group compared with the single-dose group (mean Ottawa score 3.50 ± 2.89 versus 5.96 ± 3.53;P<0.05) and resulted in less overall fluid in the colon. This effect was observed across all segments of the colon assessed.Conclusions. The current study supports use of a split-dose PEG lavage over a single large volume lavage for superior bowel cleanliness, which may improve polyp detection. This trial is registered with ClinicalTrials.gov identifierNCT01610856.

Quality and effect of single dose versus split dose of polyethylene glycol bowel preparation for early-morning colonoscopy

Endoscopy ◽  
2007 ◽  
Vol 39 (07) ◽  
pp. 616-619 ◽  
Author(s):  
J. Park ◽  
C. Sohn ◽  
S. Hwang ◽  
H. Choi ◽  
J. Park ◽  
...  
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Early Morning ◽  
Split Dose

A Single or Split Dose Picosulphate/Magnesium Citrate Before Colonoscopy: Comparison Regarding Tolerance and Eficacy with Polyethylene Glycol. A Randomized Trial

2014 ◽  
Vol 23 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Vladimir Kojecky ◽  
Jiri Dolina ◽  
Bohuslav Kianicka ◽  
Miroslav Misurec ◽  
Michal Varga ◽  
...  
Keyword(s):  
Single Dose ◽  
Polyethylene Glycol ◽  
Magnesium Citrate ◽  
Split Dose ◽  
Sodium Picosulphate ◽  
Solution Type ◽  
Bowel Cleansing ◽  
Significant Difference ◽  
Colonic Preparation

Background & Aims: To compare the eficacy and tolerance of sodium picosulphate/magnesium citrate(PMC) and polyethylene glycol (PEG) in a single or split dose regimen for colonoscopy bowel preparation.Methods: A prospective, randomized, endoscopist-blinded, multicenter study. The patients were randomly assigned to receive PMC (PMC4/0) or PEG (PEG4/0) in a single dose 4L day before colonoscopy or a split dose 2+2L PMC (PMC2/2) or 3+1L PEG (PEG3/1) one day before and in the morning before the colonoscopy. Each patient was interviewed to determine his/her subjective tolerance of the preparation before the procedure. The quality of bowel cleansing was assessed in a blinded test performed by multiple endoscopists using the Aronchick scale.Results: A total of 600 patients were enrolled, 88.2% were included in the analysis. Satisfactory bowel cleansing (Aronchick score 1 and 2) was signicantly more frequent when a split dose was used irrespective of the solution type (81.6% PMC2/2, 87.3% PEG3/1 vs. 73.0% PEG4/0, p = 0.024). In single dose regimens, PMC performed better than PEG (82.6% vs. 73.0%). Single or split dose PMC preparations were comparable. A PMC based solution was generally better tolerated than PEG regardless of the regimen used (p < 0.001). Nausea was reported mostly after the 4L PEG (32.8%, p < 0.001), incontinence after a split PMC dose (34.4%, p = 0.002), and bloating after the 4L PEG (38.0%, p < 0.001). There was no significant difference in the prevalence of vomiting.Conclusion: Colonic preparation with PMC yields similar results as a split PEG dose, regardless of whether PMC is administered in single or separate doses. PMC is better tolerated than any PEG-based preparation. A single 4L PEG the day before the colonoscopy is less appropriate for bowel cleansing.

414 Gastric Residual Volume Is Trivial Soon After Polyethylene Glycol Bowel Preparation

2013 ◽  
Vol 77 (5) ◽  
pp. AB149-AB150 ◽  
Author(s):  
Deepak Agrawal ◽  
Richard Robbins ◽  
Don C. Rockey
Keyword(s):  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Residual Volume ◽  
Gastric Residual Volume
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