The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis

Objective. This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis. Methods. 122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CEUS or Doppler ultrasound (DUS) in the diagnosis of renal artery stenosis were analyzed. The consistency between CEUS and digital subtraction angiography (DSA) was compared. The accuracy of DUS or CEUS in grading renal artery stenosis was assessed by the area under the receiver operating characteristic (ROC) curves and compared between groups. Results. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CEUS in the diagnosis of renal artery stenosis were 88.9%, 87.8%, 88.5%, 93.5%, and 80.0%, respectively. There was no significant difference in grading renal artery stenosis between CEUS and DSA (X2=0.643, P=0.424). 77 of the 122 renal arteries were diagnosed with the stenosis rate more than 30% by CEUS. Compared with the results of DSA, the kappa value of CEUS was 0.749 (P<0.05). Conclusion. CEUS is accurate in grading renal artery stenosis, and it may represent the method of choice in diagnosing renal artery stenosis.

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Qualitative analysis of contrast-enhanced ultrasound in the diagnosis of small, TR3–5 benign and malignant thyroid nodules measuring ≤1 cm

British Journal of Radiology ◽

10.1259/bjr.20190923 ◽

2020 ◽

Vol 93 (1111) ◽

pp. 20190923

Author(s):

Xin Li ◽

Feng Gao ◽

Fan Li ◽

Xiao-xia Han ◽

Si-hui Shao ◽

...

Keyword(s):

Positive Predictive Value ◽

Qualitative Analysis ◽

Negative Predictive Value ◽

Predictive Value ◽

Diagnostic Performance ◽

Thyroid Nodules ◽

Area Under The Curve ◽

Contrast Enhanced Ultrasound ◽

Contrast Enhanced ◽

Sensitivity Specificity

Objective: To evaluate the performance of contrast-enhanced ultrasound in the diagnosis of small, solid, TR3–5 benign and malignant thyroid nodules (≤1 cm). Methods: From January 2016 to March 2018, 185 thyroid nodules from 154 patients who underwent contrast enhanced ultrasound (CEUS) and fine-needle aspiration or thyroidectomy in Shanghai General Hospital were included. The χ2 test was used to compare the CEUS characteristics of benign and malignant thyroid nodules, and the CEUS features of malignant nodules assigned scores. The total score of the CEUS features and the scores of the above nodules were evaluated according to the latest 2017 version of the Thyroid Imaging Reporting and Data System (TI-RADS). The diagnostic performance of the two were compared based on the receiver operating characteristic curves generated for benign and malignant thyroid nodules. Results: The degree, enhancement patterns, boundary, shape, and homogeneity of enhancement in thyroid small solid nodules were significantly different (p＜0.05). No significant differences were seen between benign and malignant thyroid nodules regarding completeness of enhancement and size of enhanced lesions (p＞0.05). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of the TI-RADS classification TR5 in diagnosis of malignant nodules were 90.10%, 55.95%, 74.59%, 72.22%, and 82.46%, respectively (area under the curve [AUC]=0.738; 95% confidence interval[CI], 0.663–0.813). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of the total score of CEUS qualitative analysis indicators were 86.13%, 89.29%, 87.57%, 90.63%, and 84.27% respectively (AUC = 0.916; 95% CI, 0.871–0.961). Conclusion: CEUS qualitative analysis is superior to TI-RADS in evaluating the diagnostic performance of small, solid thyroid nodules. Qualitative analysis of CEUS has a significantly higher specificity for diagnosis of malignant thyroid nodules than TI-RADS. Advances in knowledge: The 2017 version of TI-RADS has recently suggested the malignant stratification of thyroid nodules by ultrasound. In this paper we applied this system and CEUS to evaluate 185 nodules and compare the results with pathological findings to access the diagnostic performance.

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Utility of color doppler ultrasound in the evaluation of renal artery stenosis in comparison with contrast-enhanced magnetic resonance angiography

Saudi Journal of Kidney Diseases and Transplantation ◽

10.4103/1319-2442.128518 ◽

2014 ◽

Vol 25 (2) ◽

pp. 309 ◽

Cited By ~ 2

Author(s):

ElnasriM Abuagla ◽

TanSook Pei

Keyword(s):

Magnetic Resonance ◽

Magnetic Resonance Angiography ◽

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Color Doppler ◽

Color Doppler Ultrasound ◽

Artery Stenosis ◽

Contrast Enhanced

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Contrast-enhanced Doppler ultrasound for renal artery stenosis

Australasian Radiology ◽

10.1046/j.1440-1673.1999.00635.x ◽

1999 ◽

Vol 43 (2) ◽

pp. 206-209 ◽

Cited By ~ 5

Author(s):

Rj Dowling Mk House Pm King Jl Bourke ◽

RN Gibson

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Artery Stenosis ◽

Contrast Enhanced

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The contrast-enhanced Doppler ultrasound with perfluorocarbon exposed sonicated albumin does not improve the diagnosis of renal artery stenosis compared with angiography

Journal of Negative Results in BioMedicine ◽

10.1186/1477-5751-3-3 ◽

2004 ◽

Vol 3 (1) ◽

Cited By ~ 5

Author(s):

Odila UN Teixeira ◽

Luiz A Bortolotto ◽

Hélio Bernardes Silva

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Artery Stenosis ◽

Contrast Enhanced

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Detection of transplant renal artery stenosis with contrast-enhanced ultrasound

Radiology Case Reports ◽

10.1016/j.radcr.2018.06.003 ◽

2018 ◽

Vol 13 (4) ◽

pp. 890-894 ◽

Cited By ~ 2

Author(s):

Gian Luigi Adani ◽

Giuseppe Como ◽

Filippo Bonato ◽

Girometti Rossano ◽

Umberto Baccarani ◽

...

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Artery Stenosis ◽

Contrast Enhanced Ultrasound ◽

Transplant Renal Artery Stenosis ◽

Contrast Enhanced

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Contrast-Enhanced Ultrasound Assessment of Renal Parenchymal Perfusion in Patients with Atherosclerotic Renal Artery Stenosis to Predict Renal Function Improvement After Revascularization

International Journal of General Medicine ◽

10.2147/ijgm.s293316 ◽

2020 ◽

Vol Volume 13 ◽

pp. 1713-1721

Author(s):

Xiuyan Wang ◽

Shuo Wang ◽

Yan-ping Pang ◽

Tian Jiang ◽

Chen Yu ◽

...

Keyword(s):

Renal Function ◽

Renal Artery ◽

Renal Artery Stenosis ◽

Artery Stenosis ◽

Contrast Enhanced Ultrasound ◽

Atherosclerotic Renal Artery Stenosis ◽

Contrast Enhanced ◽

Ultrasound Assessment

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Unenhanced breast MRI: could it replace dynamic breast MRI in detecting and characterizing breast lesions?

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-019-0103-y ◽

2020 ◽

Vol 51 (1) ◽

Cited By ~ 2

Author(s):

Reham Khalil ◽

Noha Mohamed Osman ◽

Nivine Chalabi ◽

Enas Abdel Ghany

Keyword(s):

Positive Predictive Value ◽

Diagnostic Accuracy ◽

Negative Predictive Value ◽

Predictive Value ◽

Breast Mri ◽

Breast Lesions ◽

Dce Mri ◽

Contrast Enhanced ◽

Mri Protocol ◽

Sensitivity Specificity

Abstract Background We aimed to evaluate the unenhanced MRI of the breast (UE-MRI) as an effective substitute for dynamic contrast-enhanced breast MRI (DCE-MRI) in both detecting and characterizing breast lesions. We enrolled in our retrospective study 125 females (232 breasts, as 18 patients had unilateral mastectomy) with breast mass at MRI of variable pathologies. Routine DCE-MRI protocol of the breast was conducted. We compared the conventional unenhanced images including STIR, T2, and DWIs to the DCE-MRI by two blinded radiologists, to detect and characterize breast lesions, and then we compared their results with the final reference diagnoses supplied by the histopathology or serial negative follow-ups. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy for UE-MRI and DCE-MRI were calculated. UE-MRI results of each observer were also compared with DCE- MRI. Results The calculated UE-MRI sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy for the first observer were 95%, 80%, 83%, 94%, and 89% respectively, and for the second observer, they were 94%, 79%, 81%, 93%, and 86%. On the other hand, those for the DCE-MRI by the first observer were 98%, 82%, 84%, 98%, and 90% and were 97%, 81%, 84%, 97%, and 89% by the second observer. The intraobserver agreement between the UE-MRI and DCE-MRI results of each observer was 94% and 95%, while the interobserver agreement for each section was 97.4% for UE-MRI and 98.3% for DCE-MRI. Conclusion UE-MRI of the breast can be a reliable and effective substitute for breast DCE-MRI. It can be used with comparable accuracy to DCE-MRI whenever contrast administration is not feasible or contraindicated.

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