The contrast-enhanced Doppler ultrasound with perfluorocarbon exposed sonicated albumin does not improve the diagnosis of renal artery stenosis compared with angiography

Objective. This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis. Methods. 122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CEUS or Doppler ultrasound (DUS) in the diagnosis of renal artery stenosis were analyzed. The consistency between CEUS and digital subtraction angiography (DSA) was compared. The accuracy of DUS or CEUS in grading renal artery stenosis was assessed by the area under the receiver operating characteristic (ROC) curves and compared between groups. Results. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CEUS in the diagnosis of renal artery stenosis were 88.9%, 87.8%, 88.5%, 93.5%, and 80.0%, respectively. There was no significant difference in grading renal artery stenosis between CEUS and DSA (X2=0.643, P=0.424). 77 of the 122 renal arteries were diagnosed with the stenosis rate more than 30% by CEUS. Compared with the results of DSA, the kappa value of CEUS was 0.749 (P<0.05). Conclusion. CEUS is accurate in grading renal artery stenosis, and it may represent the method of choice in diagnosing renal artery stenosis.

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Renal artery stenosis: Diagnosis using contrast-enhanced doppler ultrasound

Clinical Radiology ◽

10.1016/s0009-9260(05)81352-2 ◽

1993 ◽

Vol 48 (5) ◽

pp. 348 ◽

Cited By ~ 6

Author(s):

C.M. Allen ◽

F.G. Balen ◽

C. Missouris ◽

G. MacGregor ◽

T. Buckinham ◽

...

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Artery Stenosis ◽

Contrast Enhanced

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Contrast-Enhanced Doppler Ultrasound of Renal Artery Stenosis.

Echocardiography ◽

10.1111/j.1540-8175.1999.tb00148.x ◽

1999 ◽

Vol 16 (s1) ◽

pp. 767-773 ◽

Cited By ~ 8

Author(s):

RICCARDO LENCIONI ◽

STEFANIA PINTO ◽

DANIA CIONI ◽

CARLO BARTOLOZZI

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Artery Stenosis ◽

Contrast Enhanced

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Colour Doppler ultrasound in renal artery stenosis: intrarenal waveform analysis

British Journal of Radiology ◽

10.1259/0007-1285-69-825-810 ◽

1996 ◽

Vol 69 (825) ◽

pp. 810-815 ◽

Cited By ~ 45

Author(s):

G M Baxter ◽

F Aitchison ◽

D Sheppard ◽

J G Moss ◽

M J McLeod ◽

...

Keyword(s):

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Artery Stenosis ◽

Waveform Analysis ◽

Colour Doppler ◽

Colour Doppler Ultrasound

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Cardiovascular complications according to severity of renal artery stenosis based on Doppler ultrasound

Archives of Medical Science ◽

10.5114/aoms/132002 ◽

2021 ◽

Author(s):

Łukasz Artyszuk ◽

Bartosz Symonides ◽

Zbigniew Gaciong ◽

Cezary Szmigielski

Keyword(s):

Cardiovascular Risk ◽

Renal Artery ◽

Renal Artery Stenosis ◽

Doppler Ultrasound ◽

Cardiovascular Events ◽

Cardiovascular Complications ◽

Artery Stenosis ◽

Control Group ◽

Percutaneous Coronary Angioplasty ◽

Increased Risk

IntroductionThe interactions between atherosclerotic renal artery stenosis, independently of severity, and cardiovascular risk, and mortality, are complex and have not been fully researched. The aim of this study was the assessment of the risk of cardiovascular events and mortality in patients with haemodynamically non-significant (NS-RAS) and significant renal artery stenosis (S-RAS) diagnosed with ultrasonography.Material and methodsThe study group consisted of all consecutive patients (n = 2059) who underwent Doppler ultrasound of the renal arteries during a 4-year period. The patients were divided, according to the renal aortic ratio (RAR), into the following groups: S-RAS (RAR ≥ 3.5), NS-RAS (1 < RAR < 3.5), and normal RAR (control group; RAR ≤ 1). The risk of cardiovascular events and death was estimated using Cox’s proportional hazard model, including severity of RAS, age, and gender, based on the data from the National Health Fund on causes of hospitalization, deaths, and statistics on percutaneous coronary angioplasty procedures.ResultsSignificant renal artery stenosis was found in 112 patients (5.4%), NS-RAS in 313 patients (15.2%), and 1634 patients (79.4%) were qualified to the control group. The NS-RAS group had an increased risk of stroke (7.0% vs. 3.0%, HR = 1.77, p = 0.032); S-RAS patients were at increased risk of heart failure (16.1% vs. 5.2%, HR = 2.19, p = 0.002) and death (19.6% vs. 4.3%, HR = 3.08, p < 0.001).ConclusionsThe presence of haemodynamically non-significant renal artery stenosis is an indicator of systemic atherosclerotic changes in vital organs and an important cardiovascular risk factor for stroke.

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