scholarly journals A Privacy-Preserving Reinforcement Learning Approach for Dynamic Treatment Regimes on Health Data

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Xiaoqiang Sun ◽  
Zhiwei Sun ◽  
Ting Wang ◽  
Jie Feng ◽  
Jiakai Wei ◽  
...  

Based on the clinical states of the patient, dynamic treatment regime technology can provide various therapeutic methods, which is helpful for medical treatment policymaking. Reinforcement learning is an important approach for developing this technology. In order to implement the reinforcement learning algorithm efficiently, the computation of health data is usually outsourced to the untrustworthy cloud server. However, it may leak, falsify, or delete private health data. Encryption is a common method for solving this problem. But the cloud server is difficult to calculate encrypted health data. In this paper, based on Cheon et al.’s approximate homomorphic encryption scheme, we first propose secure computation protocols for implementing comparison, maximum, exponentiation, and division. Next, we design a homomorphic reciprocal of square root protocol firstly, which only needs one approximate computation. Based on the proposed secure computation protocols, we design a secure asynchronous advantage actor-critic reinforcement learning algorithm for the first time. Then, it is used to implement a secure treatment decision-making algorithm. Simulation results show that our secure computation protocols and algorithms are feasible.

The most data intensive industry today is the healthcare system. The advancement in technology has revolutionized the traditional healthcare practices and led to enhanced E-Healthcare System. Modern healthcare systems generate voluminous amount of digital health data. These E-Health data are shared between patients and among groups of physicians and medical technicians for processing. Due to the demand for continuous availability and handling of these massive E-Health data, mostly these data are outsourced to cloud storage. Being cloud-based computing, the sensitive patient data is stored in a third-party server where data analytics are performed, hence more concern about security raises. This paper proposes a secure analytics system which preserves the privacy of patients’ data. In this system, before outsourcing, the data are encrypted using Paillier homomorphic encryption which allows computations to be performed over encrypted dataset. Then Decision Tree Machine Learning algorithm is used over this encrypted dataset to build the classifier model. This encrypted model is outsourced to cloud server and the predictions about patient’s health status is displayed to the user on request. In this system nowhere the data is decrypted throughout the process which ensures the privacy of patients’ sensitive data.


2021 ◽  
Vol 54 (3-4) ◽  
pp. 417-428
Author(s):  
Yanyan Dai ◽  
KiDong Lee ◽  
SukGyu Lee

For real applications, rotary inverted pendulum systems have been known as the basic model in nonlinear control systems. If researchers have no deep understanding of control, it is difficult to control a rotary inverted pendulum platform using classic control engineering models, as shown in section 2.1. Therefore, without classic control theory, this paper controls the platform by training and testing reinforcement learning algorithm. Many recent achievements in reinforcement learning (RL) have become possible, but there is a lack of research to quickly test high-frequency RL algorithms using real hardware environment. In this paper, we propose a real-time Hardware-in-the-loop (HIL) control system to train and test the deep reinforcement learning algorithm from simulation to real hardware implementation. The Double Deep Q-Network (DDQN) with prioritized experience replay reinforcement learning algorithm, without a deep understanding of classical control engineering, is used to implement the agent. For the real experiment, to swing up the rotary inverted pendulum and make the pendulum smoothly move, we define 21 actions to swing up and balance the pendulum. Comparing Deep Q-Network (DQN), the DDQN with prioritized experience replay algorithm removes the overestimate of Q value and decreases the training time. Finally, this paper shows the experiment results with comparisons of classic control theory and different reinforcement learning algorithms.


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