Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

2004 ◽  
Vol 64 (16) ◽  
pp. 5882-5890 ◽  
Author(s):  
Zhen Zhang ◽  
Robert C. Bast ◽  
Yinhua Yu ◽  
Jinong Li ◽  
Lori J. Sokoll ◽  
...  
2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Qingduo Kong ◽  
Hongyi Wei ◽  
Jing Zhang ◽  
Yilin Li ◽  
Yongjun Wang

Abstract Background Laparoscopy has been widely used for patients with early-stage epithelial ovarian cancer (eEOC). However, there is limited evidence regarding whether survival outcomes of laparoscopy are equivalent to those of laparotomy among patients with eEOC. The result of survival outcomes of laparoscopy is still controversial. The aim of this meta-analysis is to analyze the survival outcomes of laparoscopy versus laparotomy in the treatment of eEOC. Methods According to the keywords, Pubmed, Embase, Cochrane Library and Clinicaltrials.gov were searched for studies from January 1994 to January 2021. Studies comparing the efficacy and safety of laparoscopy versus laparotomy for patients with eEOC were assessed for eligibility. Only studies including outcomes of overall survival (OS) were enrolled. The meta-analysis was performed using Stata software (Version 12.0) and Review Manager (Version 5.2). Results A total of 6 retrospective non-random studies were included in this meta-analysis. The pooled results indicated that there was no difference between two approaches for patients with eEOC in OS (HR = 0.6, P = 0.446), progression-free survival (PFS) (HR = 0.6, P = 0.137) and upstaging rate (OR = 1.18, P = 0.54). But the recurrence rate of laparoscopic surgery was lower than that of laparotomic surgery (OR = 0.48, P = 0.008). Conclusions Laparoscopy and laparotomy appear to provide comparable overall survival and progression-free survival outcomes for patients with eEOC. Further high-quality studies are needed to enhance this statement.


2001 ◽  
Vol 81 (2) ◽  
pp. 337 ◽  
Author(s):  
Gamal H. Eltabbakh ◽  
Pramila R. Yadev ◽  
Ann Morgan

Oncology ◽  
2011 ◽  
Vol 81 (5-6) ◽  
pp. 365-371 ◽  
Author(s):  
Aristotle Bamias ◽  
Christina Bamia ◽  
Alexandra Karadimou ◽  
Nikolaos Soupos ◽  
Flora Zagouri ◽  
...  

2014 ◽  
pp. 1-6
Author(s):  
Behrouz Zand ◽  
Ralph S. Freedman

Sign in / Sign up

Export Citation Format

Share Document