The Connectivity Map Links Iron Regulatory Protein-1–Mediated Inhibition of Hypoxia-Inducible Factor-2a Translation to the Anti-inflammatory 15-deoxy-Δ12,14-Prostaglandin J2

Cancer Research ◽

10.1158/0008-5472.can-09-2877 ◽

2010 ◽

Vol 70 (8) ◽

pp. 3071-3079 ◽

Author(s):

Michael Zimmer ◽

Justin Lamb ◽

Benjamin L. Ebert ◽

Mary Lynch ◽

Christopher Neil ◽

...

Keyword(s):

Regulatory Protein ◽

Hypoxia Inducible Factor ◽

Iron Regulatory Protein ◽

Connectivity Map ◽

Anti Inflammatory ◽

Prostaglandin J2 ◽

Iron Regulatory Protein 1

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Faculty Opinions recommendation of The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3129959.2812057 ◽

2010 ◽

Author(s):

Robert Abraham

Keyword(s):

Regulatory Protein ◽

Hypoxia Inducible Factor ◽

Iron Regulatory Protein ◽

Connectivity Map ◽

Anti Inflammatory ◽

Prostaglandin J2 ◽

Iron Regulatory Protein 1

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Faculty Opinions recommendation of The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3129959.3143055 ◽

2010 ◽

Author(s):

Tushar Patel ◽

Chiara Braconi

Keyword(s):

Regulatory Protein ◽

Hypoxia Inducible Factor ◽

Iron Regulatory Protein ◽

Connectivity Map ◽

Anti Inflammatory ◽

Prostaglandin J2 ◽

Iron Regulatory Protein 1

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The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.10.185 ◽

2018 ◽

Vol 507 (1-4) ◽

pp. 128-135 ◽

Author(s):

Lei Yang ◽

Dan Wang ◽

Xue-ting Wang ◽

Ya-peng Lu ◽

Li Zhu

Keyword(s):

Iron Uptake ◽

Acute Hypoxia ◽

Regulatory Protein ◽

Hypoxia Inducible Factor ◽

Iron Regulatory Protein ◽

Hypoxia Inducible Factor 1 ◽

Iron Regulatory Protein 1

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Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1α) and HIF-regulated genes

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2005.11.006 ◽

2006 ◽

Vol 213 (3) ◽

pp. 245-255 ◽

Author(s):

Qin Li ◽

Haobin Chen ◽

Xi Huang ◽

Max Costa

Keyword(s):

Regulatory Protein ◽

Hypoxia Inducible Factor ◽

Iron Regulatory Protein ◽

Hypoxia Inducible Factor 1 ◽

Iron Regulatory Protein 1

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Faculty Opinions recommendation of Crystal structure of human iron regulatory protein 1 as cytosolic aconitase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1030302.358477 ◽

2006 ◽

Author(s):

Peter Artymiuk

Keyword(s):

Crystal Structure ◽

Regulatory Protein ◽

Iron Regulatory Protein ◽

Iron Regulatory Protein 1

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Pro-inflammatory cytokines modulate iron regulatory protein 1 expression and iron transportation through reactive oxygen/nitrogen species production in ventral mesencephalic neurons

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ◽

10.1016/j.bbadis.2013.01.021 ◽

2013 ◽

Vol 1832 (5) ◽

pp. 618-625 ◽

Author(s):

Jia Wang ◽

Ning Song ◽

Hong Jiang ◽

Jun Wang ◽

Junxia Xie

Keyword(s):

Inflammatory Cytokines ◽

Regulatory Protein ◽

Reactive Oxygen ◽

Iron Regulatory Protein ◽

Nitrogen Species ◽

Ventral Mesencephalic ◽

Species Production ◽

Pro Inflammatory Cytokines ◽

Iron Regulatory Protein 1

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Increased Placental Iron Regulatory Protein-1 Expression in Diabetic Pregnancies Complicated by Fetal Iron Deficiency

Placenta ◽

10.1053/plac.1998.0339 ◽

1999 ◽

Vol 20 (1) ◽

pp. 87-93 ◽

Author(s):

M.K. Georgieff ◽

S.A. Berry ◽

J.D. Wobken ◽

E.A. Leibold

Keyword(s):

Iron Deficiency ◽

Regulatory Protein ◽

Iron Regulatory Protein ◽

Iron Regulatory Protein 1

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Ultraviolet-A-Dependent Inhibition of Cytoplasmic Aconitase Activity of Iron Regulatory Protein-1 in NCTC 2544 Keratinocytes

Photochemistry and Photobiology ◽

10.1111/j.1751-1097.1998.tb09686.x ◽

1998 ◽

Vol 68 (3) ◽

pp. 309-313 ◽

Author(s):

Anne Giordani ◽

Patrice Morlière ◽

Mojgan Djavaheri-Mergny ◽

René Santus

Keyword(s):

Regulatory Protein ◽

Iron Regulatory Protein ◽

Ultraviolet A ◽

Aconitase Activity ◽

Dependent Inhibition ◽

Iron Regulatory Protein 1

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The Hairpin Loop but Not the Bulged C of the Iron Responsive Element Is Essential for High Affinity Binding to Iron Regulatory Protein-1

Journal of Biological Chemistry ◽

10.1074/jbc.m010295200 ◽

2001 ◽

Vol 276 (18) ◽

pp. 14791-14796 ◽

Author(s):

Heather A. Meehan ◽

Gregory J. Connell

Keyword(s):

Regulatory Protein ◽

Affinity Binding ◽

Iron Regulatory Protein ◽

Hairpin Loop ◽

High Affinity Binding ◽

High Affinity ◽

Iron Responsive Element ◽

Responsive Element ◽

Iron Regulatory Protein 1

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The solution structure of apo-iron regulatory protein 1

Gene ◽

10.1016/j.gene.2013.03.112 ◽

2013 ◽

Vol 524 (2) ◽

pp. 341-346 ◽

Author(s):

O'Neil Shand ◽

Karl Volz

Keyword(s):

Solution Structure ◽

Regulatory Protein ◽

Iron Regulatory Protein ◽

Iron Regulatory Protein 1

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