P3-06-06: Comparison of Gene Expression Profiles of Lymph Node Positive and Lymph Node Negative ER Positive Breast Tumors in Pre- and Postmenopausal Women.

2011 ◽  
Author(s):  
PB Rapuri ◽  
L Xing ◽  
G Brilhart ◽  
B Deyarmin ◽  
L Kvecher ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Postmenopausal Women ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Breast Tumors ◽  
Node Negative ◽  
Node Positive ◽  
Er Positive ◽  
Lymph Node Positive

Gene expression profiles of primary breast tumors maintained in lymph node- and distant metastases

2004 ◽  
Vol 2 (3) ◽  
pp. 125
Author(s):  
B Weigelt ◽  
A.M Glas ◽  
L.F Wessels ◽  
A.T Witteveen ◽  
A.J Bosma ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Distant Metastases ◽  
Breast Tumors

scholarly journals Differential Gene Expression in Primary Breast Tumors Associated with Lymph Node Metastasis

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Rachel E. Ellsworth ◽  
Lori A. Field ◽  
Brad Love ◽  
Jennifer L. Kane ◽  
Jeffrey A. Hooke ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Breast Tumors ◽  
Host Susceptibility ◽  
Prognostic Indicators ◽  
Lymph Node Status ◽  
Primary Tumors ◽  
Node Negative ◽  
Node Positive ◽  
Node Status

Lymph node status remains one of the most useful prognostic indicators in breast cancer; however, current methods to assess nodal status disrupt the lymphatic system and may lead to secondary complications. Identification of molecular signatures discriminating lymph node-positive from lymph node-negative primary tumors would allow for stratification of patients requiring surgical assesment of lymph nodes. Primary breast tumors from women with negative () and positive () lymph node status matched for possible confounding factors were subjected to laser microdissection and gene expression data generated. Although ANOVA analysis (, fold-change >1.5) revealed 13 differentially expressed genes, hierarchical clustering classified 90% of node-negative but only 66% of node-positive tumors correctly. The inability to derive molecular profiles of metastasis in primary tumors may reflect tumor heterogeneity, paucity of cells within the primary tumor with metastatic potential, influence of the microenvironment, or inherited host susceptibility to metastasis.

Gene Expression Profiling in Lymph Node-Positive and Lymph Node-Negative Pancreatic Cancer

Pancreas ◽  
2007 ◽  
Vol 34 (3) ◽  
pp. 325-334 ◽  
Author(s):  
Han Na Kim ◽  
Dong Wook Choi ◽  
Kyu Taek Lee ◽  
Jong Kyun Lee ◽  
Jin Seok Heo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pancreatic Cancer ◽  
Lymph Node ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Node Negative ◽  
Node Positive ◽  
Lymph Node Positive

Gene Expression Profiling in Lymph Node-Positive and Lymph Node-Negative Colorectal Cancer

2004 ◽  
Vol 47 (2) ◽  
pp. 141-152 ◽  
Author(s):  
Hyuk-Chan Kwon ◽  
Sung-Hyun Kim ◽  
Mee-Sook Roh ◽  
Jae-Seok Kim ◽  
Hyung-Sik Lee ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Lymph Node ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Node Negative ◽  
Node Positive ◽  
Lymph Node Positive

scholarly journals Gene Expression Profiles Associated with the Presence of a Fibrotic Focus and the Growth Pattern in Lymph Node–Negative Breast Cancer

2008 ◽  
Vol 14 (10) ◽  
pp. 2944-2952 ◽  
Author(s):  
Gert G. Van den Eynden ◽  
Marcel Smid ◽  
Steven J. Van Laere ◽  
Cecile G. Colpaert ◽  
Ilse Van der Auwera ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Lymph Node ◽  
Growth Pattern ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Node Negative ◽  
Fibrotic Focus ◽  
Node Negative Breast Cancer

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

The Lancet ◽  
2005 ◽  
Vol 365 (9460) ◽  
pp. 671-679 ◽  
Author(s):  
Yixin Wang ◽  
Jan GM Klijn ◽  
Yi Zhang ◽  
Anieta M Sieuwerts ◽  
Maxime P Look ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Lymph Node ◽  
Distant Metastasis ◽  
Primary Breast Cancer ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Node Negative

Abstract SS1-07: Gene expression profiles of Ghanaian and Ethiopian triple-negative breast tumors

2021 ◽  
Author(s):  
Rachel Martini ◽  
Endale Gebregzabher ◽  
Princesca Dorsaint ◽  
Timothy Chu ◽  
Kanika Arora ◽  
...  
Keyword(s):  
Gene Expression ◽  
Triple Negative ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Breast Tumors
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