Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways

Cell Death Pathways ◽

Faculty Opinions recommendation of HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003672.38258 ◽

2002 ◽

Author(s):

John Abrams

Keyword(s):

Cell Death ◽

Serine Protease ◽

Protease Activity ◽

Inhibitor Of Apoptosis ◽

Motoneuron Resistance to Apoptotic Cell Death In Vivo Correlates with the Ratio between X-Linked Inhibitor of Apoptosis Proteins (XIAPs) and Its Inhibitor, XIAP-Associated Factor 1

Journal of Neuroscience ◽

10.1523/jneurosci.0413-04.2004 ◽

2004 ◽

Vol 24 (15) ◽

pp. 3777-3785 ◽

Cited By ~ 28

Author(s):

D. Perrelet

Keyword(s):

Cell Death ◽

Apoptotic Cell ◽

Apoptotic Cell Death ◽

Inhibitor Of Apoptosis ◽

Associated Factor ◽

Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases

International Journal of Oncology ◽

10.3892/ijo.2012.1715 ◽

2012 ◽

Vol 42 (2) ◽

pp. 444-452 ◽

Cited By ~ 12

Author(s):

INEZ L. CREGAN ◽

ARUN M. DHARMARAJAN ◽

SIMON A. FOX

Keyword(s):

Cell Death ◽

Malignant Mesothelioma ◽

Inhibitor Of Apoptosis ◽

Inhibitor of Apoptosis Proteins, the Sentinels of Cell Death and Signaling

Encyclopedia of Cell Biology ◽

10.1016/b978-0-12-394447-4.30052-9 ◽

2016 ◽

pp. 390-398

Author(s):

M. Cristina de Almagro ◽

D. Vucic

Keyword(s):

Cell Death ◽

Inhibitor Of Apoptosis ◽

Faculty Opinions recommendation of HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003672.42056 ◽

2002 ◽

Author(s):

Yigong Shi

Keyword(s):

Cell Death ◽

Serine Protease ◽

Protease Activity ◽

Inhibitor Of Apoptosis ◽

149 Resveratrol Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Cell Death - Possible Key Role of Inhibitor of Apoptosis Proteins

Gastroenterology ◽

10.1016/s0016-5085(08)60131-6 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-26

Author(s):

Sandra Ulrich ◽

Martina Kempf ◽

Jürgen Stein

Keyword(s):

Colorectal Cancer ◽

Cell Death ◽

Cancer Cells ◽

Inhibitor Of Apoptosis ◽

Colorectal Cancer Cells ◽

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion

The Journal of Immunology ◽

10.4049/jimmunol.1701620 ◽

2018 ◽

Vol 200 (10) ◽

pp. 3341-3346 ◽

Cited By ~ 14

Author(s):

Kaiwen W. Chen ◽

Kate E. Lawlor ◽

Jessica B. von Pein ◽

Dave Boucher ◽

Motti Gerlic ◽

...

Keyword(s):

Cell Death ◽

Cutting Edge ◽

Inhibitor Of Apoptosis ◽

Faculty Opinions recommendation of HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003672.17572 ◽

2001 ◽

Author(s):

Bruce Hay

Keyword(s):

Cell Death ◽

Serine Protease ◽

Protease Activity ◽

Inhibitor Of Apoptosis ◽

Faculty Opinions recommendation of Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733068955.793555147 ◽

2019 ◽

Author(s):

Michael McDermott ◽

Heledd Jarosz-Griffiths

Keyword(s):

Cell Death ◽

Cutting Edge ◽

Inhibitor Of Apoptosis ◽

HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins

Journal of Biological Chemistry ◽

10.1074/jbc.m109891200 ◽

2001 ◽

Vol 277 (1) ◽

pp. 445-454 ◽

Cited By ~ 375

Author(s):

Anne M. Verhagen ◽

John Silke ◽

Paul G. Ekert ◽

Miha Pakusch ◽

Hitto Kaufmann ◽

...

Keyword(s):

Cell Death ◽

Serine Protease ◽

Protease Activity ◽

Inhibitor Of Apoptosis ◽