KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling

2008 ◽  
Vol 7 (6) ◽  
pp. 1494-1505 ◽  
Author(s):  
Rentian Feng ◽  
Huihui Ma ◽  
Christian A. Hassig ◽  
Joseph E. Payne ◽  
Nicholas D. Smith ◽  
...  
Keyword(s):  
Dna Damage ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Mitochondrial Signaling ◽  
Deacetylase Inhibitor

Expression of Leukemia-Associated Fusion Proteins Increases Sensitivity to Histone Deacetylase Inhibitor–Induced DNA Damage and Apoptosis

2013 ◽  
Vol 12 (8) ◽  
pp. 1591-1604 ◽  
Author(s):  
Luca A. Petruccelli ◽  
Filippa Pettersson ◽  
Sonia V. del Rincón ◽  
Cynthia Guilbert ◽  
Jonathan D. Licht ◽  
...  
Keyword(s):  
Dna Damage ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Fusion Proteins ◽  
Deacetylase Inhibitor

The chemopreventive activity of the histone deacetylase inhibitor tributyrin in colon carcinogenesis involves the induction of apoptosis and reduction of DNA damage

2014 ◽  
Vol 276 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Renato Heidor ◽  
Kelly Silva Furtado ◽  
Juliana Festa Ortega ◽  
Tiago Franco de Oliveira ◽  
Paulo Eduardo Latorre Martins Tavares ◽  
...  
Keyword(s):  
Dna Damage ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Colon Carcinogenesis ◽  
Deacetylase Inhibitor ◽  
Induction Of Apoptosis ◽  
Chemopreventive Activity

scholarly journals Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

2008 ◽  
Vol 7 (10) ◽  
pp. 3285-3297 ◽  
Author(s):  
Roberto R. Rosato ◽  
Jorge A. Almenara ◽  
Sonia C. Maggio ◽  
Stefanie Coe ◽  
Peter Atadja ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Dna Damage ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Deacetylase Inhibitor
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