Abstract P207: BBP-398, a potent, small molecule inhibitor of SHP2, enhances the response of established NSCLC xenografts to KRASG12C and mutEGFR inhibitors

Mapping Intimacies ◽

10.1158/1535-7163.targ-21-p207 ◽

2021 ◽

Author(s):

James P. Stice ◽

Sofia Donovan ◽

Yuting Sun ◽

Nancy Kohl ◽

Barbara Czako ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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Faculty Opinions recommendation of Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021658.247635 ◽

2004 ◽

Author(s):

William Kaelin

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Shh Pathway ◽

Molecule Inhibitor

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Faculty Opinions recommendation of Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025625.322882 ◽

2005 ◽

Author(s):

James Stivers

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1033159.375732 ◽

2006 ◽

Author(s):

Berl R Oakley

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.520680 ◽

2007 ◽

Author(s):

Nathanael Gray

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.519039 ◽

2007 ◽

Author(s):

Tarun Kapoor

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Actin Assembly ◽

Molecule Inhibitor ◽

Identification And Characterization

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Faculty Opinions recommendation of Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5059957.4994055 ◽

2010 ◽

Author(s):

Michael Weber ◽

Daniel G Gioeli

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Amino Terminus ◽

Recurrent Prostate Cancer ◽

Molecule Inhibitor

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Faculty Opinions recommendation of A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717957380.793461863 ◽

2012 ◽

Author(s):

Pengbo Zhou ◽

Jeffrey Hannah

Keyword(s):

Multiple Myeloma ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Myeloma Cells ◽

Molecule Inhibitor ◽

Specific Protease ◽

Ubiquitin Specific Protease

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Faculty Opinions recommendation of Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717959626.793462957 ◽

2012 ◽

Author(s):

Mark Searcey

Keyword(s):

Small Molecule ◽

Tumor Regression ◽

Small Molecule Inhibitor ◽

Complete Tumor Regression ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726171812.793535824 ◽

2017 ◽

Author(s):

WH Wilson Tang

Keyword(s):

Hypertrophic Cardiomyopathy ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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