Abstract CT010: Phase I trial combining the PARP inhibitor olaparib (Ola) and AKT inhibitor AZD5363 (AZD) in germline (g)BRCA and non-BRCA mutant (m) advanced cancer patients (pts) incorporating noninvasive monitoring of cancer mutations

2016 ◽  
Author(s):  
Vasiliki Michalarea ◽  
Desam Roda ◽  
Yvette Drew ◽  
Suzanne Carreira ◽  
Brent S. O’Carrigan ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Phase I Trial ◽  
Parp Inhibitor ◽  
Noninvasive Monitoring ◽  
Advanced Cancer Patients ◽  
Akt Inhibitor ◽  
Cancer Mutations

Final results of a first-in-human phase I trial of PBI-05204, an inhibitor of AKT, FGF-2, NF-Kb, and p70S6K in advanced cancer patients.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 3023-3023 ◽  
Author(s):  
H. A. Henary ◽  
R. Kurzrock ◽  
G. S. Falchook ◽  
A. Naing ◽  
S. L. Moulder ◽  
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Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Phase I Trial ◽  
Advanced Cancer Patients

A phase I trial with recombinant interferon γ (Roussel UCLAF) in advanced cancer patients

1990 ◽  
Vol 32 (1) ◽  
pp. 67-70 ◽  
Author(s):  
François Boue ◽  
Zulay Pastran ◽  
Marc Spielmann ◽  
Thierry Le Chevalier ◽  
Rosana Subirana ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Phase I Trial ◽  
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Advanced Cancer Patients ◽  
Recombinant Interferon

Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients

2015 ◽  
Vol 64 (9) ◽  
pp. 1159-1173 ◽  
Author(s):  
Maria Grazia Cusi ◽  
Cirino Botta ◽  
Pierpaolo Pastina ◽  
Maria Grazia Rossetti ◽  
Elena Dreassi ◽  
...  
Keyword(s):  
Phase I ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Thymidylate Synthase ◽  
Phase I Trial ◽  
Advanced Cancer Patients ◽  
Epitope Peptide

scholarly journals Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2- and Non–BRCA1/2-Mutant Cancers

2020 ◽  
Vol 10 (10) ◽  
pp. 1528-1543 ◽  
Author(s):  
Timothy A. Yap ◽  
Rebecca Kristeleit ◽  
Vasiliki Michalarea ◽  
Stephen J. Pettitt ◽  
Joline S.J. Lim ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
Parp Inhibitor ◽  
Akt Inhibitor
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