Abstract 284: Design, synthesis and biological evaluation of novel water-soluble salts of the antimitotic prodrugs 4-(3-alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides selectively bioactivated by cytochrome p450 1A1 in breast cancer cells

2021 ◽  
Author(s):  
Vincent Ouellette ◽  
Atziri Corin Chavez Alvarez ◽  
Sébastien Fortin
Keyword(s):  
Breast Cancer ◽  
Cytochrome P450 ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Biological Evaluation ◽  
Water Soluble ◽  
Soluble Salts ◽  
Cytochrome P450 1A1 ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals 4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells

2018 ◽  
Vol 26 (18) ◽  
pp. 5045-5052 ◽  
Author(s):  
Atziri Corin Chavez Alvarez ◽  
Mitra Zarifi Khosroshahi ◽  
Marie-France Côté ◽  
Mathieu Gagné-Boulet ◽  
Sébastien Fortin
Keyword(s):  
Breast Cancer ◽  
Cytochrome P450 ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Cytochrome P450 1A1

scholarly journals Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25517-25528
Author(s):  
Ahmad Junaid ◽  
Felicia Phei Lin Lim ◽  
Edward R. T. Tiekink ◽  
Anton V. Dolzhenko
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Anticancer Agents ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
3D Qsar ◽  
Qsar Model ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

New highly potent and selective 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed and prepared using the 3D-QSAR model developed earlier.

Steroidal N-Sulfonylimidates: Synthesis and biological evaluation in breast cancer cells

2019 ◽  
Vol 179 ◽  
pp. 694-706 ◽  
Author(s):  
Yulia A. Volkova ◽  
Andrey S. Kozlov ◽  
Marya K. Kolokolova ◽  
Denis Y. Uvarov ◽  
Sergey A. Gorbatov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

New Thiophene Analogues of Kenpaullone: Synthesis and Biological Evaluation in Breast Cancer Cells.

ChemInform ◽  
2005 ◽  
Vol 36 (52) ◽  
Author(s):  
Laurent Brault ◽  
Evelyne Migianu ◽  
Adrien Neguesque ◽  
Eric Battaglia ◽  
Denyse Bagrel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation
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