Abstract B44: Targeting Notch signaling with a dual Notch 2/3 antagonist, OMP-59R5, inhibits tumor growth and decreases cancer stem cell frequency in pancreatic cancer.

2012 ◽  
Author(s):  
Wan-Ching Yen ◽  
Marcus Fischer ◽  
Aaron Sato ◽  
Min Wang ◽  
Ann M. Kapoun ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Tumor Growth ◽  
Notch Signaling ◽  
Cell Frequency

Abstract 3048: OMP-59R5 (Anti-Notch2/3) inhibits tumor growth and reduces cancer stem cell frequency in patient derived SCLC xenografts

2014 ◽  
Author(s):  
Marcus M. Fischer ◽  
Jalpa Shah ◽  
Jennifer Cain ◽  
Belinda Cancilla ◽  
James W. Evans ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Tumor Growth ◽  
Cell Frequency

scholarly journals PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth

Oncotarget ◽  
2015 ◽  
Vol 6 (31) ◽  
pp. 32039-32060 ◽  
Author(s):  
Narinder Sharma ◽  
Rajesh Nanta ◽  
Jay Sharma ◽  
Sumedha Gunewardena ◽  
Karan P. Singh ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Tumor Growth ◽  
Sonic Hedgehog ◽  
Human Pancreatic Cancer

Inhibition of pancreatic cancer stem cell characteristics and tumor growth by Gli inhibitor GANT61

Pancreatology ◽  
2013 ◽  
Vol 13 (2) ◽  
pp. e11
Author(s):  
J. Fu ◽  
S.K. Roy ◽  
J. Sharma ◽  
S. Shankar ◽  
R.K. Srivastava
Keyword(s):  
Pancreatic Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Tumor Growth
Sign in / Sign up

Export Citation Format

Share Document