Role of Oxygen Radicals in Experimental Acute Pancreatitis

1992 ◽  
Vol 24 (1) ◽  
pp. 74-84 ◽  
Author(s):  
M.H. Schoenberg ◽  
M. Büchler ◽  
M. Helfen ◽  
H.G. Beger
HPB Surgery ◽  
1995 ◽  
Vol 8 (4) ◽  
pp. 237-239
Author(s):  
E. Akpinar ◽  
I. Özden ◽  
N. Savci ◽  
A. Emre

The role of free oxygen radicals in experimental acute pancreatitis induced by common bile duct ligation was investigated by measuring malondialdehyde levels in the rat pancreas. Also, the potential role of leucocytes as the source of free oxygen radicals was tested by inducing leukopenia with methotrexate. The malondialdehyde levels in the control, pancreatitis and pancreatitis + methotrexate groups were 9.6 ± 2.0, 44.8 ± 11.4, and 25.6 ± 5.0 nmol malondialdehyde/ g pancreas tissue respectively. The corresponding histopathological severity scores were 0.5 ± 0.7, 8.1 ± 1.2 and 3.7 ± 1.1. The results suggest that the leucocyte may be an important source of free oxygen radicals in this experimental model.


1992 ◽  
Vol 12 (6) ◽  
pp. 515-522 ◽  
Author(s):  
M.H. Schoenberg ◽  
M. Büchler ◽  
H.G. Beger

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e324-e325
Author(s):  
P. Miguel ◽  
J. Camelione ◽  
L. Cardozo Bidart ◽  
R. Trapani ◽  
P. Curvale ◽  
...  

2016 ◽  
Vol 50 (12) ◽  
pp. 1350-1360 ◽  
Author(s):  
Fabíula Francisca Abreu ◽  
Ana Carla Araújo Souza ◽  
Simone Aparecida Teixeira ◽  
Antônio Garcia Soares ◽  
Daiane Franco Teixeira ◽  
...  

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