Effects of Neonatally Administered Chlorpromazine and Reserpine on the Responsiveness of Rat Hepatic Drug-Metabolising Enzymes to Testosterone in Adult Life

Neonatology ◽  
1986 ◽  
Vol 50 (5) ◽  
pp. 265-269
Author(s):  
Michael J. Finnen ◽  
Kenneth A. Hassall
1989 ◽  
Vol 8 (1-4) ◽  
Author(s):  
Thomothy T. Iyaniwura

SummaryEnvironmental chemicals are capable of interaction with each other and with endogenous substances to minimize or augment their individual toxicities. Interaction between chemicals could take place via the absorption, distribution and excretory routes. Induction and inhibition of the hepatic drug metabolising enzymes also play a significant role in chemical activation, detoxification and interactions. Knowledge of the various mechanisms of toxicity of combined exposure to chemical compounds, in the work or natural environment, are invaluable in predicting their human hazards.


1985 ◽  
Vol 28 (2-3) ◽  
pp. 143-149 ◽  
Author(s):  
P. Bentley ◽  
W. Stäubli ◽  
F. Bieri ◽  
W. Muecke ◽  
F. Waechter

Toxicology ◽  
1985 ◽  
Vol 37 (3-4) ◽  
pp. 259-266 ◽  
Author(s):  
Ramesh Rajpurohit ◽  
R. Kalamegham ◽  
A.K. Chary ◽  
Kamala Krishnaswamy

1974 ◽  
Vol 19 (1) ◽  
pp. 57-58
Author(s):  
CHARLES R. STROTHER
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document