Elevated Macrophage Inflammatory Protein 1a and Interleukin-17 Production in an Experimental Asthma Model Infected with Respiratory Syncytial Virus

2013 ◽  
Vol 161 (s2) ◽  
pp. 129-137 ◽  
Author(s):  
Taisei Ishioka ◽  
Yoshiyuki Yamada ◽  
Hirokazu Kimura ◽  
Masakazu Yoshizumi ◽  
Hiroyuki Tsukagoshi ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Interleukin 17 ◽  
Asthma Model ◽  
Inflammatory Protein ◽  
Syncytial Virus ◽  
Macrophage Inflammatory Protein

scholarly journals Inhibitory Effect of Ferulic Acid and Isoferulic Acid on the Production of Macrophage Inflammatory Protein-2 in Response to Respiratory Syncytial Virus Infection in RAW264.7 Cells

1999 ◽  
Vol 8 (3) ◽  
pp. 173-175 ◽  
Author(s):  
S. Sakai ◽  
H. Kawamata ◽  
T. Kogure ◽  
N. Mantani ◽  
K. Terasawa ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Ferulic Acid ◽  
Dependent Manner ◽  
Inflammatory Drug ◽  
Inflammatory Protein ◽  
Isoferulic Acid ◽  
Infected Cells ◽  
Anti Inflammatory ◽  
Syncytial Virus ◽  
Macrophage Inflammatory Protein

We investigated the effect of ferulic acid (FA) and isoferulic acid (IFA), which are the main active components of the rhizoma ofCimicifuga heracleifolia(CH), an anti-inflammatory drug used frequently in Japanese traditional medicine, on the production of macrophage inflammatory protein-2 (MIR-2) in a murine macrophage cell line, RAW264.7, in response to respiratory syncytial virus (RSV) infection. Following the exposure of cells to RSV for 20 h, the MIP-2 level in condition medium was increased to about 20 ng/ml, although this level in mock-infected cells was negligible. In the presence of either FA or IFA, RSV-infected cells reduced MIP-2 production in a dose-dependent manner. These data suggest that FA and IFA might be responsible, at least in part, for the anti-inflammatory drug effect of CH extract through the inhibition of MIP-2 production.

Compounds with anti-respiratory syncytial virus activity from endophytic fungus Pestalotiopsis thea

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
PF Uzor ◽  
DC Odimegwu ◽  
W Ebrahim ◽  
PO Osadebe ◽  
NJ Nwodo ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Endophytic Fungus ◽  
Virus Activity ◽  
Syncytial Virus

Influence of Previous Respiratory Infection on the Association between Respiratory Syncytial Virus Hospitalization and Childhood Asthma

2020 ◽  
Author(s):  
Richard Thwaites ◽  
Jonathan Coutts ◽  
John Fullarton ◽  
ElizaBeth Grubb ◽  
Carole Morris ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Infection ◽  
Childhood Asthma ◽  
Syncytial Virus
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