Metachronous Development of Meningothelial Meningioma, Basal Cell Carcinoma, and Glioblastoma Multiforme in a Patient with Pancreatic Incidentaloma

We report the unique case of a 61-year-old male patient with known pancreatic incidentaloma who additionally developed 3 other histologically different tumors: left sphenoid wing meningothelial meningioma, basal cell carcinoma of the occiput, and right occipital lobe glioblastoma multiforme. The latter were totally removed with a favorable clinical outcome. The patient’s family history was unremarkable, and no data on any previous head and neck irradiation were found.

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Coexisting Basal Cell Carcinoma and Squamous Cell Carcinoma in Congenital Nevus Sebaceous

SKIN The Journal of Cutaneous Medicine ◽

10.25251/skin.2.3.6 ◽

2018 ◽

Vol 2 (3) ◽

pp. 181-185

Author(s):

Jordan Rosen ◽

Katherine Nolan ◽

Noah Shaikh ◽

Les Rosen ◽

Martin Zaiac

Keyword(s):

Squamous Cell Carcinoma ◽

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Basal Cell ◽

Squamous Cell Carcinomas ◽

Malignant Neoplasms ◽

Rare Occurrence ◽

Unique Case ◽

Nevus Sebaceous

Nevus sebaceous is a congenital epidermal hamartoma characterized by hyperplastic changes to the epidermis and adnexa. Nevus sebaceous is associated with an elevated risk of cutaneous neoplasms, most often benign; however, malignant neoplasms, most notably basal cell carcinoma, can also present in these patients. Although a rare occurrence, more often affecting adult patients, squamous cell carcinomas have also been reported to arise at the site of pre-existing nevus sebaceous. Herein we report a unique case of a patient with basal cell carcinoma and squamous cell carcinoma arising concurrently in the same nevus sebaceous.

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Nonsyndromic Type of Multiple Basal Cell Carcinoma

International Journal of Head and Neck Surgery ◽

10.5005/jp-journals-10001-1005 ◽

2010 ◽

Vol 1 (1) ◽

pp. 25-28

Author(s):

D'Cruz Anil ◽

Chaturvedi Pankaj ◽

Chaukar Devendra ◽

Ghatge Amit ◽

Pai Prathamesh ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Chemical Warfare ◽

Unique Case ◽

Actinic Keratoses ◽

The Face ◽

Multiple Variable ◽

History Of ◽

Indian Male

Abstract We report a case of nonsyndromic type of multiple basal cell carcinoma associated purely with actinic keratoses. A 69-year-old Indian male had suffered from multiple, variable-sized papules and nodules on the face, neck and chest for 13 years previous to treatment. He had no history of arsenic intake, irradiation, herb medication, or exposure to chemical warfare gases. Family histories for basal cell carcinoma and xeroderma pigmentosum were negative. Classical features of Gorlin's syndrome were conspicuous by their absence. Histopathologically, the tumors revealed typical findings of basal cell carcinoma arising from actinic keratoses. The case in point is a very rare and unique case in itself as being nonsyndromic, nonhereditary and occurring in the absence of various other environmental conditions as already mentioned in literature.

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Basal Cell Carcinoma Arising within a Trichoepithelioma: An Immunohistochemical Study

Acta Medica Martiniana ◽

10.2478/acm-2020-0008 ◽

2020 ◽

Vol 20 (2) ◽

pp. 64-71

Author(s):

V. Bartos

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Tumor Type ◽

Lumbar Region ◽

Unique Case ◽

Ki 67 ◽

Resected Tumor ◽

Peripheral Cells ◽

Neoplastic Epithelium

AbstractBackground: Trichoepithelioma (TE) and basal cell carcinoma (BCC) of skin represent distinct tumor entities but they have a close histogenetic and phenotypic relationship.Objective: A unique case of a BCC arising within a TE is described with an emphasis on the analysis of different and for each tumor type typical immunophenotype.Material and Methods: A 71-year-old man presented with a subcutaneous solid tumor in the lumbar region. The resected tumor specimen was studied by immunohistochemistry.Results: Histology revealed a coexistence of classic TE and nodular BCC. Both tumors were strongly positive for BerEP4 and negative for EMA. Neoplastic epithelium of the BCC showed a diffuse staining for Bcl-2, while the TE expressed Bcl-2 almost exclusively in the peripheral cells of tumor islands. In the BCC, neoplastic nodules exhibited a focal staining for CD10, while the peritumorous stroma did not. In contrast, the TE showed a focal immunoreactivity for CD10 in the stromal cells around the neoplastic islands which were completely negative. The TE contained intratumorous CK20-labeled Merkel cells but they were not detected in the BCC. A stromal immunore-activity for CD34 was found in both tumors. Proliferative activity (Ki-67) was slightly higher in the BCC than in the TE.Conclusion: Although a concomitant presence of TE and BCC in the same skin lesion is a unique finding, it may be sometimes encountered in a biopsy practice. Pathologists should provide a careful histologic examination of the whole TE lesion with precise section sampling to unveil such possible association.

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Ultrastructure of Mouse Basal Cell Carcinoma Exhibiting Sebaceous Differentiation

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s1431927600003214 ◽

1980 ◽

Vol 38 ◽

pp. 738-739

Author(s):

Victoria L. Wade ◽

Winslow G. Sheldon ◽

James W. Townsend ◽

William Allaben

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Topical Application ◽

Basal Cell ◽

Sebaceous Gland ◽

Rats And Mice ◽

Mixed Tumors

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.

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