Nachsorge und palliative Operation

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2012 ◽  
Vol 60 (S 01) ◽  
Author(s):  
V Dirks ◽  
K Kassem ◽  
E Valsangiacomo ◽  
W Knirsch ◽  
C Mueller ◽  
...  
Keyword(s):  


2006 ◽  
Vol 19 (01) ◽  
Author(s):  
H Ptok ◽  
F Marusch ◽  
L Meyer ◽  
I Gastinger






2020 ◽  
Vol 8 ◽  
pp. 2050313X2092203
Author(s):  
Takahiro Kubo ◽  
Yosuke Aihara ◽  
Hideto Kawaratani ◽  
Tadashi Namisaki ◽  
Ryuichi Noguchi ◽  
...  

The prognosis of congenital heart disease is dramatically improved by cardiac surgery. The Fontan procedure is the definitive palliative operation for patients with single-ventricle physiology. In parallel with the longer survival time achieved with the Fontan procedure, the incidence of Fontan-associated liver disease is increasing. A 40-year-old man who underwent Fontan procedures at the ages of 9 was referred to our hospital for further evaluation of multiple hepatic tumors. Enhanced computed tomography showed large hepatocellular carcinomas with portal thrombi (Vp3). Spontaneous hepatocellular carcinoma rupture occurred 2 weeks after the first visit to our hospital, and emergent transcatheter arterial embolization of the hepatic artery was performed. Three months later, the patient died of liver failure. Autopsy findings showed moderately differentiated hepatocellular carcinoma with a cirrhotic liver characterized by centrilobular fibrosis and sinusoidal dilation similar to that in Fontan-associated liver disease. We reported the first case of spontaneously ruptured hepatocellular carcinoma treated by emergent transcatheter arterial embolization in Fontan-associated liver disease. As the early diagnosis of liver cirrhosis and hepatocellular carcinoma results in better patients’ outcome, cardiologists and hepatologists should be aware of Fontan-associated liver disease and advise patients to have regular follow-up of the liver.



1975 ◽  
Vol 69 (4) ◽  
pp. 579-584 ◽  
Author(s):  
Ellis L. Jones ◽  
William H. Plauth ◽  
Charles R. Hatcher


2003 ◽  
Vol 13 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Håkan Wåhlander ◽  
Andreas Westerlind ◽  
Göran Lindstedt ◽  
Per-Arne Lundberg ◽  
Daniel Holmgren

We evaluated the concentrations of the brain and atrial natriuretic peptides in the plasma as markers of ventricular function and volume load in children with functionally univentricular hearts. We studied 7 children aged from 0.5 to 0.7 years with functionally univentricular hearts who had undergone a first palliative operation, and 10 children aged from 1.8 to 3.7 years who had undergone a bidirectional Glenn anastomosis at ages ranging from 0.4 to 1.0 year. As a control group, we studied 14 children without heart defects aged from 0.1 to 4.5 years. Levels of the brain natriuretic peptide were measured at 8.3 to 122 ng/l, with a mean of 52.8 ng/l, after the first palliative operation, compared to 0 to 16 ng/l, with a mean of 7.3 ng/l, after a bidirectional Glenn anastomosis, and 0 to 13.8 ng/l, with a mean of 5.9 ng/l, in the children serving as controls. Corresponding values for atrial natriuretic peptide were 17 to 203 ng/l, with a mean of 103 ng/l, after the first palliative operation, compared to 16 to 54 ng/l, with a mean of 29 ng/l, after the bidirectional Glenn anastomosis, and 12 to 52 ng/l, with a mean of 32 ng/l in the controls. Echocardiography showed that all the children with functionally univentricular hearts had normal ventricular function. Blood presssure, pulmonary arterial pressure, and arterial saturations of oxygen did not differ between the groups. We conclude, that in children with functionally univentricular hearts, the volume overload imposed on the heart after the first palliative operation is associated with increased production of brain and atrial natriuretic peptides, while after ventricular unloading, levels of the natriuretic peptides return to control values.



2008 ◽  
Vol 394 (1) ◽  
pp. 199-204 ◽  
Author(s):  
Klaus Buttenschoen ◽  
Beate Gruener ◽  
Daniela Carli Buttenschoen ◽  
Stefan Reuter ◽  
Doris Henne-Bruns ◽  
...  


2014 ◽  
Vol 13 (3) ◽  
pp. 184-191
Author(s):  
Jonas Jurgaitis ◽  
Marius Kryžauskas ◽  
Viktor Asejev ◽  
Juozas Stanaitis ◽  
Marius Paškonis ◽  
...  

ĮvadasMechaninė gelta, kuri dažniausiai yra pirmasis kasos galvos vėžio simptomas, pasireiškia 90 % atvejų. Radikalus chirurginis gydymo būdas įmanomas tik 15–20 % ligonių, todėl taikomi paliatyvūs gydymo metodai: tulžies latakų stentavimas arba bi­liodigestyvinių jungčių suformavimas. Abu gydymo metodai yra lygiaverčiai ir nėra kriterijų, kurie leistų pasirinkti vieną iš jų.Ligoniai ir metodaiAtliktas retrospektyvusis tyrimas. Ligoniai, kuriems diagnozuotas kasos galvos navikas ir pasireiškė mechaninė gelta, buvo suskirstyti į dvi grupes pagal atliktą paliatyvaus gydymo metodą: A grupę sudarė ligoniai, kuriems buvo stentuoti tulžies latakai, B grupę – ligoniai, kuriems atlikta biliodigestyvinė anastomozė. Analizuoti klinikiniai duomenys, komplikacijos, išgy­venamumas, vidutinė ligonio gydymo kaina.RezultataiĮ tyrimą įtraukti 182 ligoniai: 94 (52 %) – atliktas endoskopinis tulžies latakų stentavimas ir 88 (48 %) – suformuota biliodiges­tyvinė anastomozė. A grupės pacientų vidutinis išgyvenamumas buvo mažesnis nei B grupės pacientų – atitinkamai 106,5 (6–705) ir 188,5 (1–744) dienos (p=0,026). Tolimosios metastazės nustatytos 34 (36 %) A grupės ligoniams ir 30 (34 %) – B grupės. Abiejų grupių ligonių, turinčių metastazių, išgyvenamumas mažai kuo skyrėsi: A grupės ligonių – 84,5 (6–354) dienos, o B grupės – 82,5 (9–542) dienos, p=0,38. Komplikacijų pasireiškė 17 % A grupės ir 19 % B grupės ligonių. A grupės paciento vidutinės gydymo išlaidos sudarė 6491 Lt, B grupės – 11 627 Lt.IšvadosIšplitęs kasos galvos navikas su tolimomis metastazėmis lemia trumpesnį išgyvenamumą, todėl šiems ligoniams rekomen­duojama stentuoti tulžies latakus. Esant neoperabiliems kasos galvos navikams be metastazių, indikuojama biliodigestyvinė anastomozė.Reikšminiai žodžiai: kasos galvos vėžys, mechaninė gelta, stentavimas, biliodigestyvinė anastomozė Biliary tract obstruction in nonresectable tumour of pancreatic head. Stenting or palliative operation?Jonas Jurgaitis, Marius Kryžauskas, Viktor Asejev, Juozas Stanaitis, Marius Paškonis, Virgilijus Beiša, Kęstutis Strupas BackgroundObstructive jaundice, which usually is the first symptom of tumour of the pancreatic head, occurs in 90% of cases. Due to the fact that radical surgery is possible only for 15–20% of patients, obstructive jaundice is treated by applying palliative methods (endoscopic biliary tract stenting or biliodigestive anastomosis). Both palliative methods are equal, and there are no criteria that would determine the option of treatment.Matherials and methodsA retrospective analysis of patients with a pancreatic head tumour and obstructive jaundice was made. Patients were divided into two groups according to the applied palliative method: group A – biliary tract stenting, group B – biliodigestive anasto­mosis. Clinical data, complications, the survival of patients and the average cost of treatment for one patient were compared.Results182 patients were involved in the analysis, of them 94 (52 %) underwent biliary tract stenting and 88 (48%) biliodigestive anastomosis. The median of the survival of patients in group A was shorter than in group B – 106.5 (6–705) versus 188.5 (1–744) days, p = 0.026. Distant metastases were determined in 34 (36 %) patients of group A and in 30 (34%) of group B. The median survival of patients with distant metastases was approximately equal: in group A – 84.5 (6–354) days, in group B – 82.5 (9–542), p = 0.38. Complications in group A occurred in 17%, and in group B in 19% of cases. The average cost of treatment reached 6491 Lt for one patient in group A and 11 627 Lt in group B.ConclusionsAdvanced tumour of pancreatic head with distant metastases is a condition for a shorter survival; thus, biliary tract stenting is indicated. Inoperable tumour of pancreatic head without distant metastases is an indication for applying a biliodigestive anastomosis.Key words: tumour of pancreatic head, obstructive jaundice, stenting, biliodigestive anastomosis



2010 ◽  
Vol 71 (9) ◽  
pp. 2310-2315 ◽  
Author(s):  
Yuu OHTANI ◽  
Shinichi OKA ◽  
Kazuo KURAYOSHI ◽  
Kikuhiro KOHNO ◽  
Hiroshi YOSHIOKA ◽  
...  


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