Editorial: From Passive to Active Regeneration: The New Gold Standard in Bone and Soft Tissue Grafting

2021 ◽  
Vol 41 (6) ◽  
pp. 794-796
Author(s):  
Samuel Lynch
Keyword(s):  
Soft Tissue ◽  
Gold Standard ◽  
Active Regeneration

Percutaneous Imaging-Guided versus Open Musculoskeletal Biopsy: Concepts and Controversies

2020 ◽  
Vol 24 (06) ◽  
pp. 667-675
Author(s):  
Violeta Vasilevska Nikodinovska ◽  
Slavcho Ivanoski ◽  
Milan Samardziski ◽  
Vesna Janevska
Keyword(s):  
Soft Tissue ◽  
Complication Rate ◽  
Core Needle Biopsy ◽  
Multidisciplinary Team ◽  
Gold Standard ◽  
Needle Biopsy ◽  
Soft Tissue Tumors ◽  
Open Biopsy ◽  
Core Needle ◽  
Similar Accuracy

AbstractBone and soft tissue tumors are a largely heterogeneous group of tumors. Biopsy of musculoskeletal (MSK) tumors is sometimes a challenging procedure. Although the open biopsy is still considered the gold standard for the biopsy of MSK lesions, core needle biopsy can replace it in most cases, with similar accuracy and a low complication rate. The biopsy should be performed in a tertiary sarcoma center where the multidisciplinary team consists of at minimum a tumor surgeon, an MSK pathologist, and an MSK radiologist who can assess all steps of the procedure. Several factors can influence the success of the biopsy including the lesion characteristics, the equipment, and the method used for the procedure. This review highlights some of the important aspects regarding the biopsy of the MSK tumors, with special attention to imaging a guided core needle biopsy and highlighting some of the recent advancements and controversies in the field.

Pain management and intraocular pressure monitoring following phacoemulsification

2021 ◽  
Vol 12 (10) ◽  
pp. 478-482
Author(s):  
Louise Lee ◽  
Evie Yon
Keyword(s):  
Intraocular Pressure ◽  
Pain Management ◽  
Soft Tissue ◽  
Pain Assessment ◽  
Postoperative Care ◽  
Gold Standard ◽  
Standard Procedure ◽  
Hospital Setting ◽  
Nursing Interventions ◽  
Pressure Monitoring

Phacoemulsification is the gold standard procedure for cataract removal in veterinary patients. Registered veterinary nurses involved in the care of patients undergoing this surgery should be aware of potential complications postoperatively and tailor their nursing considerations to individual patients. Pain assessment in ophthalmic patients should take a different format to that in traditional soft tissue or orthopaedic surgeries, and monitoring of intraocular pressure is an important part of postoperative care. This report aims to discuss these nursing interventions for a patient nursed in a referral hospital setting.

scholarly journals The Forehead Flap: The Gold Standard of Nasal Soft Tissue Reconstruction

2013 ◽  
Vol 27 (02) ◽  
pp. 096-103 ◽  
Author(s):  
Bryan Correa ◽  
William Weathers ◽  
Erik Wolfswinkel ◽  
James Thornton
Keyword(s):  
Soft Tissue ◽  
Gold Standard ◽  
Soft Tissue Reconstruction ◽  
Forehead Flap ◽  
Tissue Reconstruction

Diagnostic gold standard for soft tissue tumours: morphology or molecular genetics?

2001 ◽  
Vol 39 (1) ◽  
pp. 100-101 ◽  
Author(s):  
C D M Fletcher ◽  
J A Fletcher ◽  
P D Cin ◽  
M Ladanyi ◽  
J M Woodruff
Keyword(s):  
Soft Tissue ◽  
Molecular Genetics ◽  
Gold Standard ◽  
Soft Tissue Tumours

Overgrowth of soft tissues after transplantation of a connective tissue graft for the treatment of gingival recession

2020 ◽  
Vol 13 (12) ◽  
pp. e238816
Author(s):  
Igor Ashurko ◽  
Eduard Levonian ◽  
Ilia Dementev ◽  
Svetlana Tarasenko
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Connective Tissue ◽  
Gold Standard ◽  
Hard Palate ◽  
Soft Tissues ◽  
Gingival Recession ◽  
Connective Tissue Graft ◽  
Tissue Graft

The application of free connective tissue graft (CTG) is the gold standard in the treatment of gingival recession in the area of teeth and implants. The aim of this case report is to demonstrate a possible mucosal overgrowth complication in the soft tissue grafting area. A 24-year-old patient underwent the treatment of gingival recession in the tooth 2.3 region by an envelope technique using a free CTG from the hard palate region. Seven years after the surgery, a mucosal overgrowth was observed, which developed asymptomatically and did not cause any problems to the patient.

scholarly journals 3221 Optimization of chondrogenesis on 3-dimensionally printed porous tissue bioscaffolds for auricular tissue engineering

2019 ◽  
Vol 3 (s1) ◽  
pp. 18-18
Author(s):  
Brian Chang ◽  
Zahra Nourmahammadi ◽  
Ashley Cornett ◽  
Isabelle Lombaert ◽  
David Zopf
Keyword(s):  
Soft Tissue ◽  
Gold Standard ◽  
Patient Specific ◽  
Type I ◽  
Auricular Cartilage ◽  
Auricular Reconstruction ◽  
Current Gold Standard ◽  
Composite Gel ◽  
3D Printed ◽  
And Cartilage

OBJECTIVES/SPECIFIC AIMS: This study’s aims are to optimize the isolation and growth of chondrocytes from pig auricular cartilage; to identify the ideal seeding conditions onto 3D printed auricular bioscaffolds to maximize chondrocyte growth; and to investigate what quantity and types of host tissue can grow on the bioscaffold. Primary outcomes will include comparisons between different seeding conditions in various objective measures of bioscaffold growth and survival as listed in the methods section. Secondary outcomes will include continued optimization of bioscaffolds to minimize extrusion rates and maximize morphologic and histologic similarity to human auricular cartilage. METHODS/STUDY POPULATION: For chondrocyte-seeded scaffolds, cartilage will be collected from freshly harvested porcine auricular tissue and digested in type II collagenase. Chondrocytes derived from the harvest will be seeded into auricular PCL scaffolds using a type I collagen/hyaluronic acid composite gel, which has been previously shown to support chondrogenesis. For scaffolds containing cartilage, punch biopsies will be collected and embedded in specific areas of the scaffold previously shown to experience excessive stress/strain compared to the rest of the construct. From there, five of each chondrocyte-seeded bioscaffolds, chondrocyte-unseeded bioscaffolds, and cartilage-containing bioscaffolds will be implanted into athymic rats. Total follow up will be for six months, with outcomes as measured by clinical assessments, morphologic measurements, radiological imaging, histological analysis, biomechanical evaluation, and photodocumentation. Once these measures are obtained, we will work closely with Dr. Myra Kim, an adjunct professor with the Biostatistics Department, to appropriately analyze differences between the models. RESULTS/ANTICIPATED RESULTS: We believe that while all scaffolds (chondrocyte-seeded, chondrocyte-unseeded, and cartilage-containing) will be structurally sound, the chondrocyte-seeded scaffolds and cartilage-containing scaffolds will exhibit improved soft tissue coverage and have lower exposure and fracture rates. Additionally, between the two, we posit that there will not be appreciable differences histologically, radiologically, or morphologically. DISCUSSION/SIGNIFICANCE OF IMPACT: Auricular reconstruction is a geometrically complex and technically challenging problem. Reconstruction hinges on the physical characteristics of the deformity, patient preferences, and reconstructive materials available. The current gold standard for auricular reconstruction uses autologous rib cartilage as foundational support for overlying soft tissue and these techniques involve freehand carving of the cartilage, requiring high levels of technical skill. Harvesting the materials for this procedure is invasive, and the outcomes of the surgery are largely variable and sometimes undesirable. As alternatives, implantable scaffolds including those made from high density porous polyethylene (commercially referred to as MedPor) have been investigated. However, many of these have proven inadequate due to factors including infection, extrusion, and morphologic and biomechanical dissimilarity from native tissue. 3D printing represents an exciting new avenue through which to address many of these difficulties. Our group has previously demonstrated the successful design, production, and implantation of 3D-printed models: in auricular reconstruction, we have demonstrated the successful creation and implementation of a 3D printed ear scaffold into an athymic rodent model. We now turn our attention to optimization of seeding of our ear scaffold with chondrocytes derived from porcine auricular cartilage or with cartilage punch biopsies, all while maintaining emphasis on regulatory feasibility. With success in this arena, we will be able to provide a much less invasive and technically challenging alternative to the current gold standard, create patient-specific bioscaffolds which are more form fitting and individualized, and provide children with ear malformations better alternatives and treatments for their conditions.

scholarly journals Harvesting of autogenous grafts for gingival recession coverage

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Peter Windisch ◽  
Balint Molnar
Keyword(s):  
Soft Tissue ◽  
Gold Standard ◽  
Standard Treatment ◽  
Donor Site ◽  
Gingival Recession ◽  
Soft Tissue Graft ◽  
Tissue Grafts ◽  
Periodontal Plastic Surgery ◽  
Soft Tissue Grafts ◽  
Autogenous Grafts

Abstract The ultimate aim of periodontal plastic surgery is to create optimal pink esthetics through the reconstruction of gingival recessions. Application of autogenous soft tissue grafts is considered as a gold standard treatment modality with predictable esthetic outcomes for gingival recession coverage. Harvesting a free soft tissue graft from an esthetically irrelevant region of the oral mucosa using various techniques can prevent donor site complications around the adjacent teeth.

scholarly journals Development of a model of soft tissue simulation using ballistic gelatin for CBCT acquisitions related to dentomaxillofacial radiology research

2020 ◽  
pp. 20200191
Author(s):  
Eduarda Helena Leandro Nascimento ◽  
Rocharles Cavalcante Fontenele ◽  
Priscila de Azeredo Lopes ◽  
Gustavo Machado Santaella ◽  
Karla Faria Vasconcelos ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Gold Standard ◽  
Soft Tissues ◽  
Cone Beam Ct ◽  
Acrylic Resin ◽  
Standard Group ◽  
Significant Difference ◽  
New Material ◽  
Ballistic Gelatin ◽  
The Mean

Objectives: To present the ballistic gelatin as a new material capable of simulating the soft tissues in cone-beam CT (CBCT) images. Methods: CBCT images of three piglet heads were acquired with their soft tissues intact (standard group). Subsequently, the piglet heads were fixed in a container using metallic pins and moulded with acrylic resin; the soft tissues were then removed and replaced by ballistic gelatin, with the same thickness of the original soft tissues. The images were evaluated by two oral radiologists, to check the adaptation on bone surfaces, thickness and density, penetration into large bone cavities and cancellous bone, and the presence of air bubbles using a 5-score scale. Additionally, an objective analysis was carried out by one oral radiologist. For each CBCT scan, three axial reconstructions were selected to represent the mandibular, occlusal, and maxillary levels. The mean and standard deviation (SD) of the grey values were calculated in four regions of interest determined on soft tissue areas and compared by two-way ANOVA. Results: The ballistic gelatin showed subjective scores ranging from good to excellent for all parameters evaluated. There was no significant difference in the mean and SD values of the grey values between ballistic gelatin and the gold standard groups for all levels (p > 0.05). Higher SD values were observed in the occlusal level for both groups (p < 0.05). Conclusions: Ballistic gelatin has visual and objective similarity with the gold standard. Thus, the ballistic gelatin is a promising material capable of simulating soft tissues in CBCT images.

Diagnostic gold standard for soft tissue tumours: morphology or molecular genetics?

2000 ◽  
Vol 37 (6) ◽  
pp. 485-500 ◽  
Author(s):  
J D Pfeifer ◽  
D A Hill ◽  
M J O'sullivan ◽  
L P Dehner
Keyword(s):  
Soft Tissue ◽  
Molecular Genetics ◽  
Gold Standard ◽  
Soft Tissue Tumours

Systemic treatment of soft-tissue sarcoma—gold standard and novel therapies

2014 ◽  
Vol 11 (4) ◽  
pp. 187-202 ◽  
Author(s):  
Mark Linch ◽  
Aisha B. Miah ◽  
Khin Thway ◽  
Ian R. Judson ◽  
Charlotte Benson
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Gold Standard ◽  
Systemic Treatment ◽  
Novel Therapies
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