scholarly journals Incremental Prognostic Value of Post-Stress Left Ventricular Ejection Fraction and Volume by Gated Myocardial Perfusion Single Photon Emission Computed Tomography

Circulation ◽  
1999 ◽  
Vol 100 (10) ◽  
pp. 1035-1042 ◽  
Author(s):  
Tali Sharir ◽  
Guido Germano ◽  
Paul B. Kavanagh ◽  
Shenhan Lai ◽  
Ishac Cohen ◽  
...  
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Emission Computed Tomography ◽  
Ventricular Ejection Fraction ◽  
Myocardial Perfusion Single Photon ◽  
Single Photon Emission Computed ◽  
Incremental Prognostic Value ◽  
Photon Emission Computed Tomography

scholarly journals Comparison of left ventricular ejection fraction values obtained using invasive contrast left ventriculography, two-dimensional echocardiography, and gated single-photon emission computed tomography

2016 ◽  
Vol 4 ◽  
pp. 205031211665594 ◽  
Author(s):  
Nadish Garg ◽  
Thomas Dresser ◽  
Kul Aggarwal ◽  
Vishal Gupta ◽  
Mayank K Mittal ◽  
...  
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Emission Computed Tomography ◽  
Ventricular Ejection Fraction ◽  
Single Photon Emission Computed ◽  
Dimensional Echocardiography ◽  
Two Dimensional Echocardiography ◽  
Photon Emission Computed Tomography

Objectives: Left ventricular ejection fraction can be measured by a variety of invasive and non-invasive cardiac techniques. This study assesses the relation of three diagnostic modalities to each other in the measurement of left ventricular ejection fraction: invasive contrast left ventriculography, two-dimensional echocardiography, and quantitative gated single-photon emission computed tomography. Methods: Retrospective chart review was conducted on 58 patients hospitalized with chest pain, who underwent left ventricular ejection fraction evaluation using each of the aforementioned modalities within a 3-month period not interrupted by myocardial infarction or revascularization. Results: The mean left ventricular ejection fraction values were as follows: invasive contrast left ventriculography (0.44±0.15), two-dimensional echocardiography (0.46±0.13), and gated single-photon emission computed tomography (0.37±0.10). Correlations coefficients and associated p values were as follows: invasive contrast left ventriculography versus two-dimensional echocardiography (r=0.69, p<0.001), invasive contrast left ventriculography versus gated single-photon emission computed tomography (r=0.80, p<0.0001), and gated single-photon emission computed tomography versus two-dimensional echocardiography (r=0.69, p<0.001). Conclusion: Our results indicate that strong positive correlations exist among the three techniques studied.

scholarly journals Prognostic Value of Phase Analysis for Predicting Adverse Cardiac Events Beyond Conventional Single-Photon Emission Computed Tomography Variables: Results From the REFINE SPECT Registry

2021 ◽  
Author(s):  
Keiichiro Kuronuma ◽  
Robert J.H. Miller ◽  
Yuka Otaki ◽  
Serge D. Van Kriekinge ◽  
Marcio A. Diniz ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Ventricular Ejection Fraction ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Background: Phase analysis of single-photon emission computed tomography myocardial perfusion imaging provides dyssynchrony information which correlates well with assessments by echocardiography, but the independent prognostic significance is not well defined. This study assessed the independent prognostic value of single-photon emission computed tomography-myocardial perfusion imaging phase analysis in the largest multinational registry to date across all modalities. Methods: From the REFINE SPECT (Registry of Fast Myocardial Perfusion Imaging With Next Generation SPECT), a total of 19 210 patients were included (mean age 63.8±12.0 years and 56% males). Poststress total perfusion deficit, left ventricular ejection fraction, and phase variables (phase entropy, bandwidth, and SD) were obtained automatically. Cox proportional hazards analyses were performed to assess associations with major adverse cardiac events (MACE). Results: During a follow-up of 4.5±1.7 years, 2673 (13.9%) patients experienced MACE. Annualized MACE rates increased with phase variables and were ≈4-fold higher between the second and highest decile group for entropy (1.7% versus 6.7%). Optimal phase variable cutoff values stratified MACE risk in patients with normal and abnormal total perfusion deficit and left ventricular ejection fraction. Only entropy was independently associated with MACE. The addition of phase entropy significantly improved the discriminatory power for MACE prediction when added to the model with total perfusion deficit and left ventricular ejection fraction ( P <0.0001). Conclusions: In a largest to date imaging study, widely representative, international cohort, phase variables were independently associated with MACE and improved risk stratification for MACE beyond the prediction by perfusion and left ventricular ejection fraction assessment alone. Phase analysis can be obtained fully automatically, without additional radiation exposure or cost to improve MACE risk prediction and, therefore, should be routinely reported for single-photon emission computed tomography-myocardial perfusion imaging studies.

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