Impaired Nitric Oxide–Mediated Renal Vasodilation in Rats With Experimental Heart Failure

Circulation ◽  
1997 ◽  
Vol 96 (10) ◽  
pp. 3655-3664 ◽  
Author(s):  
Zaid A. Abassi ◽  
Konstantin Gurbanov ◽  
Susan E. Mulroney ◽  
Clariss Potlog ◽  
Terry J. Opgenorth ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Experimental Heart Failure

Activity of the L-Arginine/Nitric Oxide Pathway and Endothelin-1 in Experimental Heart Failure

1994 ◽  
Vol 23 (6) ◽  
pp. 976 ◽  
Author(s):  
Georg Noll ◽  
Marcel R. Tschudi ◽  
Dragutin Novosel ◽  
Thomas F. Lüscher
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Endothelin 1 ◽  
Experimental Heart Failure ◽  
Nitric Oxide Pathway

scholarly journals Nitric oxide–sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction

JCI Insight ◽  
2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Nicola Wilck ◽  
Lajos Markó ◽  
András Balogh ◽  
Kristin Kräker ◽  
Florian Herse ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Ejection Fraction ◽  
Guanylyl Cyclase ◽  
Preserved Ejection Fraction ◽  
Experimental Heart Failure

Apoptosis and Inducible Nitric Oxide Synthase in Experimental Heart Failure in Rabbits

2000 ◽  
Vol 99 (s43) ◽  
pp. 7P-7P
Author(s):  
DA MacDougall ◽  
S Currie ◽  
A McPhaden ◽  
SM Cobbe ◽  
AJB Brady
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Experimental Heart Failure ◽  
Oxide Synthase ◽  
Inducible Nitric Oxide

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

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