scholarly journals "Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow.

1989 ◽  
Vol 64 (1) ◽  
pp. 86-96 ◽  
Author(s):  
K Przyklenk ◽  
R A Kloner
Keyword(s):  
Blood Flow ◽  
Superoxide Dismutase ◽  
Free Radicals ◽  
Myocardial Blood Flow ◽  
Contractile Function ◽  
Myocardial Infarct ◽  
Regional Myocardial Blood Flow ◽  
Myocardial Infarct Size ◽  
Oxygen Derived Free Radicals ◽  
Regional Myocardial Blood

scholarly journals Regional myocardial blood flow after sudden aortic constriction in awake dogs.

1978 ◽  
Vol 42 (3) ◽  
pp. 419-425 ◽  
Author(s):  
A Walston ◽  
J C Rembert ◽  
J M Fedor ◽  
J C Greenfield
Keyword(s):  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Regional Myocardial Blood Flow ◽  
Aortic Constriction ◽  
Regional Myocardial Blood

Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs

1986 ◽  
Vol 250 (3) ◽  
pp. H372-H377 ◽  
Author(s):  
G. J. Gross ◽  
N. E. Farber ◽  
H. F. Hardman ◽  
D. C. Warltier
Keyword(s):  
Blood Flow ◽  
Superoxide Dismutase ◽  
Free Radicals ◽  
Oxygen Free Radicals ◽  
Ischemia Reperfusion ◽  
Free Radical Scavengers ◽  
Stunned Myocardium ◽  
Regional Myocardial Blood Flow ◽  
Control Group ◽  
Myocardial Segment

Recent evidence suggests that oxygen free radicals may partially mediate irreversible ischemia-reperfusion injury in the myocardium. In the present study, the effect of a combination of two oxygen free radical scavengers, superoxide dismutase plus catalase (SOD + CAT), on the recovery of subendocardial segment function following 15 min of coronary artery occlusion followed by 3 h of reperfusion ("stunned" myocardium) was compared with a control group in barbital-anesthetized dogs. Myocardial segment shortening (%SS) in the subendocardium of nonischemic and ischemic areas was measured by sonomicrometry and regional blood flow by radioactive microspheres. SOD and CAT were infused into the left atrium 30 min before and throughout the occlusion period. Compared with the control group, %SS in the subendocardium of the ischemic region was significantly (P less than 0.05) greater in the SOD plus CAT-treated group during occlusion and throughout reperfusion. Since there were no significant differences in hemodynamics or regional myocardial blood flow between the SOD plus CAT and the control groups, these results suggest that toxic oxygen free radicals may be partially involved in the reversible ischemic injury that occurs during short periods of coronary occlusion followed by reperfusion.

Effect of sublingually administered nitroglycerin on regional myocardial blood flow in patients with coronary artery disease

1977 ◽  
Vol 39 (5) ◽  
pp. 672-678 ◽  
Author(s):  
Peter F. Cohn ◽  
Denis Maddox ◽  
B. Leonard Holman ◽  
John E. Markis ◽  
Douglass F. Adams ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Blood Flow ◽  
Coronary Artery ◽  
Myocardial Blood Flow ◽  
Regional Myocardial Blood Flow ◽  
Artery Disease ◽  
Regional Myocardial Blood

Measurement of Regional Myocardial Blood Flow during Rapid Atrial Pacing

1973 ◽  
Vol 8 (4) ◽  
pp. 287
Author(s):  
B Leonard Holman ◽  
David Jewitt ◽  
Dougless F. Adams ◽  
Peter F. Cohn ◽  
Richard Gorlin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Myocardial Blood Flow ◽  
Regional Myocardial Blood Flow ◽  
Atrial Pacing ◽  
Regional Myocardial Blood
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